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3STL
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BU of 3stl by Molmil
KcsA potassium channel mutant Y82C with Cadmium bound
Descriptor: CADMIUM ION, POTASSIUM ION, Voltage-gated potassium channel, ...
Authors:Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E.
Deposit date:2011-07-11
Release date:2012-04-18
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels.
Structure, 20, 2012
3RVY
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BU of 3rvy by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A)
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
Authors:Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
Deposit date:2011-05-06
Release date:2011-07-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
3STZ
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BU of 3stz by Molmil
KcsA potassium channel mutant Y82C with nitroxide spin label
Descriptor: POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Voltage-gated potassium channel, ...
Authors:Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E.
Deposit date:2011-07-11
Release date:2012-04-18
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels.
Structure, 20, 2012
1ZWI
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BU of 1zwi by Molmil
Structure of mutant KcsA potassium channel
Descriptor: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
Authors:Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E.
Deposit date:2005-06-03
Release date:2006-03-07
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
3OR6
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BU of 3or6 by Molmil
On the structural basis of modal gating behavior in K+channels - E71Q
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Perozo, E.
Deposit date:2010-09-06
Release date:2011-01-05
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
3PJS
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BU of 3pjs by Molmil
Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
Descriptor: FAB heavy chain, FAB light chain, Voltage-gated potassium channel
Authors:Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E.
Deposit date:2010-11-10
Release date:2011-07-06
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism of activation gating in the full-length KcsA K+ channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OR7
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BU of 3or7 by Molmil
On the structural basis of modal gating behavior in K+channels - E71I
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Pan, A.C, Cortes, D.M, Roux, B, Perozo, E.
Deposit date:2010-09-06
Release date:2011-01-05
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
3OGC
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BU of 3ogc by Molmil
KcsA E71A variant in presence of Na+
Descriptor: SODIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ...
Authors:McCoy, J.G, Nimigean, C.M.
Deposit date:2010-08-16
Release date:2011-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism for selectivity-inactivation coupling in KcsA potassium channels.
Proc.Natl.Acad.Sci.USA, 108, 2011
1R3J
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BU of 1r3j by Molmil
potassium channel KcsA-Fab complex in high concentration of Tl+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
2BOC
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BU of 2boc by Molmil
Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs)
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
Authors:Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
Deposit date:2005-04-09
Release date:2005-04-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
1R3I
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BU of 1r3i by Molmil
potassium channel KcsA-Fab complex in Rb+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
2BOB
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BU of 2bob by Molmil
Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA)
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
Authors:Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
Deposit date:2005-04-09
Release date:2005-04-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
1R3L
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BU of 1r3l by Molmil
potassium channel KcsA-Fab complex in Cs+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
6FG3
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BU of 6fg3 by Molmil
Structure of Ryanodine receptor 1 in nanodiscs in the presence of calcium, ATP and ryanodine
Descriptor: CALCIUM ION, Ryanodine receptor 1, ZINC ION
Authors:Willegems, K, Efremov, R.G.
Deposit date:2018-01-09
Release date:2018-08-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Influence of Lipid Mimetics on Gating of Ryanodine Receptor.
Structure, 26, 2018
1S5H
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BU of 1s5h by Molmil
Potassium Channel Kcsa-Fab Complex T75C mutant in K+
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ...
Authors:Mackinnon, R, Zhou, M.
Deposit date:2004-01-20
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.
J.Mol.Biol., 338, 2004
6FOO
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BU of 6foo by Molmil
Structure of Ryanodine Receptor 1 in nanodiscs in the presence of calcium and ATP
Descriptor: Ryanodine receptor 1, ZINC ION
Authors:Willegems, K, Efremov, R.G.
Deposit date:2018-02-08
Release date:2018-08-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Influence of Lipid Mimetics on Gating of Ryanodine Receptor.
Structure, 26, 2018
2ATK
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BU of 2atk by Molmil
Structure of a mutant KcsA K+ channel
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, NONAN-1-OL, ...
Authors:Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Chakrapani, S, Roux, B, Perozo, E.
Deposit date:2005-08-25
Release date:2006-03-07
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
4H33
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BU of 4h33 by Molmil
Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes, tetragonal crystal form
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Lmo2059 protein, POTASSIUM ION
Authors:Santos, J.S, Asmar-Rovira, G.A, Han, G.W, Liu, W, Syeda, R, Cherezov, V, Baker, K.A, Stevens, R.C, Montal, M.
Deposit date:2012-09-13
Release date:2012-11-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes.
J.Biol.Chem., 287, 2012
1R3K
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BU of 1r3k by Molmil
potassium channel KcsA-Fab complex in low concentration of Tl+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
4LBE
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BU of 4lbe by Molmil
Structure of KcsA with R122A mutation
Descriptor: DIACYL GLYCEROL, Fab heavy chain, Fab light chain, ...
Authors:Nimigean, C.M, Posson, D.J, McCoy, J.M.
Deposit date:2013-06-20
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Molecular interactions involved in proton-dependent gating in KcsA potassium channels.
J.Gen.Physiol., 142, 2013
2DWE
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BU of 2dwe by Molmil
Crystal structure of KcsA-FAB-TBA complex in Rb+
Descriptor: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB HEAVY CHAIN, ANTIBODY FAB LIGHT CHAIN, ...
Authors:Yohannan, S, Zhou, Y.
Deposit date:2006-08-10
Release date:2007-02-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel
J.Mol.Biol., 366, 2007
2DWD
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BU of 2dwd by Molmil
crystal structure of KcsA-FAB-TBA complex in Tl+
Descriptor: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB HEAVY CHAIN, ANTIBODY FAB LIGHT CHAIN, ...
Authors:Yohannan, S, Zhou, Y.
Deposit date:2006-08-10
Release date:2007-02-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel
J.Mol.Biol., 366, 2007
8QUD
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BU of 8qud by Molmil
Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT5
Descriptor: (5R)-5-ethyl-3-(6-spiro[2H-1-benzofuran-3,1'-cyclopropane]-4-yloxypyridin-3-yl)imidazolidine-2,4-dione, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Chi, G, Mckinley, G, Marsden, B, Pike, A.C.W, Ye, M, Brooke, L.M, Bakshi, S, Lakshminarayana, B, Pilati, N, Marasco, A, Gunthorpe, M, Alvaro, G.S, Large, C.H, Williams, E, Sauer, D.B.
Deposit date:2023-10-16
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:The binding and mechanism of a positive allosteric modulator of Kv3 channels.
Nat Commun, 15, 2024
8QUC
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BU of 8quc by Molmil
Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT1
Descriptor: (5R)-5-ethyl-3-[6-(3-methoxy-4-methyl-phenoxy)pyridin-3-yl]imidazolidine-2,4-dione, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Chi, G, Mckinley, G, Marsden, B, Pike, A.C.W, Ye, M, Brooke, L.M, Bakshi, S, Pilati, N, Marasco, A, Gunthorpe, M, Alvaro, G, Large, C, Lakshminaraya, B, Williams, E, Sauer, D.B.
Deposit date:2023-10-16
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The binding and mechanism of a positive allosteric modulator of Kv3 channels.
Nat Commun, 15, 2024
8QZ2
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BU of 8qz2 by Molmil
Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an inhibitory nanobody (Nb61)
Descriptor: Nanobody 61, POTASSIUM ION, Potassium channel subfamily K member 10
Authors:Baronina, A, Pike, A.C.W, Rodstrom, K.E.J, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2023-10-26
Release date:2024-05-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Nat Commun, 15, 2024

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