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1X56
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii
Descriptor: Asparaginyl-tRNA synthetase
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
1X55
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii complexed with asparaginyl-adenylate analogue
Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, Asparaginyl-tRNA synthetase, MAGNESIUM ION, ...
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
1X54
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii complexed with asparaginyl-adenylate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparaginyl-tRNA synthetase, ...
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
1BBU
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LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE
Descriptor: LYSINE, PROTEIN (LYSYL-TRNA SYNTHETASE)
Authors:Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1BBW
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LYSYL-TRNA SYNTHETASE (LYSS)
Descriptor: PROTEIN (LYSYL-TRNA SYNTHETASE)
Authors:Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1ASZ
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THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER)
Authors:Cavarelli, J, Rees, B, Thierry, J.C, Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.
EMBO J., 13, 1994
1ASY
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CLASS II AMINOACYL TRANSFER RNA SYNTHETASES: CRYSTAL STRUCTURE OF YEAST ASPARTYL-TRNA SYNTHETASE COMPLEXED WITH TRNA ASP
Descriptor: ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER)
Authors:Ruff, M, Cavarelli, J, Rees, B, Krishnaswamy, S, Thierry, J.C, Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).
Science, 252, 1991
6O3F
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Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, LYSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-02-26
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand
to be published
6NS0
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Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis complexed with L-lysine and Cladosporin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-01-24
Release date:2019-02-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and Cladosporin
to be published
1C0A
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CRYSTAL STRUCTURE OF THE E. COLI ASPARTYL-TRNA SYNTHETASE : TRNAASP : ASPARTYL-ADENYLATE COMPLEX
Descriptor: ADENOSINE MONOPHOSPHATE, ASPARTYL TRNA, ASPARTYL TRNA SYNTHETASE, ...
Authors:Eiler, S, Dock-Bregeon, A.-C, Moulinier, L, Thierry, J.-C, Moras, D.
Deposit date:1999-07-15
Release date:1999-11-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis of aspartyl-tRNA(Asp) in Escherichia coli--a snapshot of the second step.
EMBO J., 18, 1999
6NRZ
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Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis complexed with L-lysine and Adenosine
Descriptor: 1,2-ETHANEDIOL, ADENOSINE, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and Adenosine
to be published
4RMF
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Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target
Descriptor: 2,2-bis(hydroxymethyl)propane-1,3-diol, Aspartate--tRNA(Asp/Asn) ligase, FORMIC ACID
Authors:Cox, J.A.G, Gurcha, S.S, Veeraraghavan, U, Besra, G.S, Futterer, K.
Deposit date:2014-10-21
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target.
Plos One, 9, 2014
6OD8
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Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Putative aspartyl-tRNA synthetase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-03-26
Release date:2019-04-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
to be published
6PQH
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Crystal structure of Asparagine-tRNA ligase from Elizabethkingia sp. CCUG 26117
Descriptor: 1,2-ETHANEDIOL, Asparagine--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-07-09
Release date:2019-07-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Asparagine-tRNA ligase from Elizabethkingia sp. CCUG 26117
TO BE PUBLISHED
4UP7
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Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with lysyl-adenylate
Descriptor: ADENOSINE-5'-[LYSYL-PHOSPHATE], LYSINE--TRNA LIGASE
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UPA
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BU of 4upa by Molmil
Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with AMPPNP
Descriptor: LYSINE--TRNA LIGASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UP9
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Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, LYSINE--TRNA LIGASE
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.047 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UP8
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Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase apo form
Descriptor: LYSINE--TRNA LIGASE
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
3A5Z
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Crystal structure of Escherichia coli GenX in complex with elongation factor P
Descriptor: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Elongation factor P, Putative lysyl-tRNA synthetase
Authors:Sumida, T, Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2009-08-17
Release date:2010-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P.
Nat.Struct.Mol.Biol., 17, 2010
3A74
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Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with Diadenosine Tetraphosphate (AP4A)
Descriptor: 2,6-DIAMINO-HEXANOIC ACID AMIDE, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Lysyl-tRNA synthetase, ...
Authors:Sakurama, H, Takita, T, Mikami, B, Itoh, T, Yasukawa, K, Inouye, K.
Deposit date:2009-09-13
Release date:2010-09-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Bacillus stearothermophilus in Complex with Diadenosine Tetraphosphate (AP4A): Insights into AP4A Synthesis Mechanisms and Implication for Recognition of Discriminator Base of tRNA^Lys
To be Published
3BJU
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Crystal Structure of tetrameric form of human lysyl-tRNA synthetase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, LYSINE, ...
Authors:Guo, M, Yang, X.L, Schimmel, P.
Deposit date:2007-12-04
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
Proc.Natl.Acad.Sci.Usa, 105, 2008
3E9I
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Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysine hydroxamate-AMP
Descriptor: 5'-O-{(R)-hydroxy[(L-lysylamino)oxy]phosphoryl}adenosine, Lysyl-tRNA synthetase, MAGNESIUM ION, ...
Authors:Sakurama, H, Takita, T, Mikami, B, Itoh, T, Yasukawa, K, Inouye, K.
Deposit date:2008-08-22
Release date:2009-07-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate
J.Biochem., 145, 2009
3E9H
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Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysylsulfamoyl adenosine
Descriptor: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysyl-tRNA synthetase, MAGNESIUM ION
Authors:Sakurama, H, Takita, T, Mikami, B, Itoh, T, Yasukawa, K, Inouye, K.
Deposit date:2008-08-22
Release date:2009-07-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate
J.Biochem., 145, 2009
1E24
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM complexed with lysine and ATP and MN2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, LYSINE, ...
Authors:Desogus, G, Todone, F, Brick, P, Onesti, S.
Deposit date:2000-05-16
Release date:2000-07-28
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E22
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM complexed with lysine and the non-hydrolysable atp analogue amp-pcp
Descriptor: GLYCEROL, LYSINE, LYSYL-TRNA SYNTHETASE, ...
Authors:Desogus, G, Todone, F, Brick, P, Onesti, S.
Deposit date:2000-05-15
Release date:2000-07-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000

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