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3Q17
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BU of 3q17 by Molmil
Structure of a slow CLC Cl-/H+ antiporter from a cyanobacterium in Bromide
Descriptor: BROMIDE ION, Sll0855 protein
Authors:Jayaram, H, Robertson, J.L, Fang, W, Williams, C, Miller, C.
Deposit date:2010-12-16
Release date:2011-01-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
4ENE
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BU of 4ene by Molmil
Structure of the N- and C-terminal trimmed ClC-ec1 Cl-/H+ antiporter and Fab Complex
Descriptor: CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, H(+)/Cl(-) exchange transporter ClcA, ...
Authors:Lim, H.H, Shane, T, Miller, C.
Deposit date:2012-04-13
Release date:2012-12-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Intracellular proton access in a cl(-)/h(+) antiporter.
Plos Biol., 10, 2012
4FG6
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BU of 4fg6 by Molmil
Structure of EcCLC E148A mutant in Glutamate
Descriptor: Fab fragment (Heavy chain), Fab fragment (Light chain), H(+)/Cl(-) exchange transporter ClcA
Authors:Feng, L, MacKinnon, R.
Deposit date:2012-06-04
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.019 Å)
Cite:Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
4KJP
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BU of 4kjp by Molmil
Structure of the CLC-ec1 deltaNC construct in the absence of halide
Descriptor: H(+)/Cl(-) exchange transporter ClcA, heavy chain of Fab fragment, light chain of Fab fragment
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KJQ
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BU of 4kjq by Molmil
Structure of the CLC-ec1 deltaNC construct in 100mM fluoride
Descriptor: FLUORIDE ION, Fab, heavy chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.875 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KJW
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BU of 4kjw by Molmil
Structure of the CLC-ec1 deltaNC construct in 100mM fluoride and 20mM bromide
Descriptor: Fab, heavy chain, light chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KK5
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BU of 4kk5 by Molmil
Structure of the CLC-ec1 deltaNC construct in 20mM fluoride and 20mM bromide
Descriptor: Fab, heavy chain, light chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.171 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KK6
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BU of 4kk6 by Molmil
Structure of CLC-ec1 deltaNC construct in 20mM Bromide
Descriptor: BROMIDE ION, Fab, heavy chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.183 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KK8
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BU of 4kk8 by Molmil
Structure of the E148Q mutant of CLC-ec1 deltaNC construct in 100mM fluoride
Descriptor: FLUORIDE ION, Fab, heavy chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KK9
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BU of 4kk9 by Molmil
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 2mM Bromide
Descriptor: Fab, heavy chain, light chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KKA
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BU of 4kka by Molmil
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 20mM Bromide
Descriptor: Fab, heavy chain, light chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KKB
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BU of 4kkb by Molmil
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM fluoride and 20mM Bromide
Descriptor: Fab, heavy chain, light chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.021 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KKC
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BU of 4kkc by Molmil
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM Bromide
Descriptor: Fab, heavy chain, light chain, ...
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KKL
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BU of 4kkl by Molmil
Structure of the E148A mutant of CLC-ec1 delta NC construct in 100mM fluoride
Descriptor: FLUORIDE ION, Fab, heavy chain, ...
Authors:Stockbridge, R.B, Lim, H.-H, Miller, C.
Deposit date:2013-05-06
Release date:2013-08-21
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4LOU
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BU of 4lou by Molmil
Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide
Descriptor: Fab heavy chain, Fab light chain, H(+)/Cl(-) exchange transporter ClcA
Authors:Lim, H.-H, Miller, C.
Deposit date:2013-07-13
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.981 Å)
Cite:A fluoride interloper in a CLC-type Cl /H+ antiporter
Nat.Chem.Biol., 2013
4MQX
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BU of 4mqx by Molmil
CLC-ec1 Fab Complex Cysless A399C-A432C mutant
Descriptor: CHLORIDE ION, ERIC, H(+)/Cl(-) exchange transporter ClcA, ...
Authors:Basilio, D, Noack, K, Picollo, A, Accardi, A.
Deposit date:2013-09-16
Release date:2014-04-16
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (3.516 Å)
Cite:Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.
Nat.Struct.Mol.Biol., 21, 2014
5HD8
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BU of 5hd8 by Molmil
Crystal structure of disulfide cross-linked D417C ClC-ec1
Descriptor: CHLORIDE ION, FAB FRAGMENT (HEAVY CHAIN), FAB FRAGMENT (LIGHT CHAIN), ...
Authors:Mathews, I.I, Khantwal, C.M, Maduke, M.
Deposit date:2016-01-05
Release date:2017-01-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Conformational change in CLC transporters: beyond the rotation of Gluex
To be published
5TQQ
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BU of 5tqq by Molmil
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation
Descriptor: Chloride channel protein, Monoclonal antibody, Fab fragment, ...
Authors:Park, E, MacKinnon, R.
Deposit date:2016-10-24
Release date:2017-01-04
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
5TR1
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BU of 5tr1 by Molmil
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
Descriptor: CHOLESTEROL HEMISUCCINATE, Chloride channel protein, Monoclonal antibody, ...
Authors:Park, E, MacKinnon, R.
Deposit date:2016-10-25
Release date:2017-01-11
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
6AD7
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BU of 6ad7 by Molmil
Crystal structure of the E148D mutant CLC-ec1 in 20 mM bromide
Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ...
Authors:Lim, H.-H, Park, K.
Deposit date:2018-07-31
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6AD8
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BU of 6ad8 by Molmil
Crystal structure of the E148D mutant CLC-ec1 in 50 mM bromide
Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ...
Authors:Lim, H.-H, Park, K.
Deposit date:2018-07-31
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6ADA
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BU of 6ada by Molmil
Crystal structure of the E148D mutant CLC-ec1 in 200mM bromide
Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, ...
Authors:Lim, H.-H, Park, K.
Deposit date:2018-07-31
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.153 Å)
Cite:Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6ADB
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BU of 6adb by Molmil
Crystal structure of the E148N mutant CLC-ec1 in 20mM bromide
Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, ...
Authors:Lim, H.-H, Park, K.
Deposit date:2018-07-31
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6ADC
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BU of 6adc by Molmil
Crystal structure of the E148A mutant CLC-ec1 in the presence of 50mM bromoacetate
Descriptor: H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, heavy chain, ...
Authors:Lim, H.-H, Park, K.
Deposit date:2018-07-31
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.055 Å)
Cite:Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
6COY
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BU of 6coy by Molmil
Human CLC-1 chloride ion channel, transmembrane domain
Descriptor: CHLORIDE ION, Chloride channel protein 1
Authors:Park, E, MacKinnon, R.
Deposit date:2018-03-13
Release date:2018-06-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structure of the CLC-1 chloride channel fromHomo sapiens.
Elife, 7, 2018

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