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7R2M
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BU of 7r2m by Molmil
SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, GLYCEROL, ...
Authors:Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G.
Deposit date:2022-02-04
Release date:2023-05-17
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:PDZome-wide and structural characterization of the PDZ-binding motif of VANGL2.
Biochim Biophys Acta Proteins Proteom, 1872, 2024
1QAV
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BU of 1qav by Molmil
Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of NNOS-Syntrophin Complex
Descriptor: ALPHA-1 SYNTROPHIN (RESIDUES 77-171), NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130)
Authors:Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A.
Deposit date:1999-03-30
Release date:1999-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex.
Science, 284, 1999
4UU6
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BU of 4uu6 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
7NTK
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BU of 7ntk by Molmil
PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ...
Authors:Javorsky, A, Kvansakul, M.
Deposit date:2021-03-10
Release date:2021-06-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
7NTJ
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BU of 7ntj by Molmil
PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex
Descriptor: Envelope small membrane protein, MAGUK p55 subfamily member 5
Authors:Javorsky, A, Kvansakul, M.
Deposit date:2021-03-10
Release date:2021-06-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
5K4F
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BU of 5k4f by Molmil
CAL PDZ mutant C319A with a peptide
Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, HPV18E6 peptide
Authors:Zhao, Y, Madden, D.R.
Deposit date:2016-05-20
Release date:2017-08-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:CAL PDZ domain mutant with a peptide
To Be Published
8OEP
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BU of 8oep by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
Descriptor: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
Deposit date:2023-03-11
Release date:2023-05-10
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
2AWW
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BU of 2aww by Molmil
Synapse associated protein 97 PDZ2 domain variant C378G with C-terminal GluR-A peptide
Descriptor: 18-residue C-terminal peptide from glutamate receptor, ionotropic, AMPA1, ...
Authors:Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K.
Deposit date:2005-09-02
Release date:2006-08-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
2AIN
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BU of 2ain by Molmil
Solution structure of the AF-6 PDZ domain complexed with the C-terminal peptide from the Bcr protein
Descriptor: 6-mer peptide from Breakpoint cluster region protein, Afadin
Authors:Chen, Q, Wu, J, Shi, Y.
Deposit date:2005-07-30
Release date:2006-07-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex.
Protein Sci., 16, 2007
5JXB
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BU of 5jxb by Molmil
PSD-95 extended PDZ3 in complex with SynGAP PBM
Descriptor: Disks large homolog 4,SynGAP
Authors:Shang, Y, Zhang, M.
Deposit date:2016-05-13
Release date:2016-09-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.
Cell, 166, 2016
6BXG
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BU of 6bxg by Molmil
1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
Descriptor: CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ...
Authors:Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-12-18
Release date:2018-01-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
To Be Published
6EEY
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BU of 6eey by Molmil
Crystal structure of human Scribble PDZ4 R1110G Mutant
Descriptor: Protein scribble homolog
Authors:Janezic, E.M, Hsu, P, Hague, C.
Deposit date:2018-08-15
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.145 Å)
Cite:Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands.
Sci Rep, 9, 2019
8GI4
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BU of 8gi4 by Molmil
Crystal structure of human LIMK2 PDZ domain
Descriptor: LIM domain kinase 2
Authors:Casanova Sepulveda, G, Boggon, T.J.
Deposit date:2023-03-13
Release date:2023-12-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Autoregulation of the LIM kinases by their PDZ domain.
Nat Commun, 14, 2023
1GQ4
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BU of 1gq4 by Molmil
STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR
Descriptor: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
Authors:Karthikeyan, S, Leung, T, Ladias, J.A.A.
Deposit date:2001-11-19
Release date:2002-05-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
6EZI
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BU of 6ezi by Molmil
PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
Descriptor: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2
Authors:Loew, C, Flayhan, A, Pieprzyk, J.
Deposit date:2017-11-15
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.503321 Å)
Cite:Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution.
Structure, 26, 2018
1GQ5
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BU of 1gq5 by Molmil
Structural Determinants of the NHERF Interaction with beta2-AR and PDGFR
Descriptor: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
Authors:Karthikeyan, S, Leung, T, Ladias, J.A.A.
Deposit date:2001-11-20
Release date:2002-11-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
6ESP
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BU of 6esp by Molmil
Proteome-wide analysis of phospho-regulated PDZ domain interactions
Descriptor: Protein scribble homolog
Authors:Chi, N.C.
Deposit date:2017-10-24
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Proteome-wide analysis of phospho-regulated PDZ domain interactions.
Mol. Syst. Biol., 14, 2018
6GBD
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BU of 6gbd by Molmil
Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain
Descriptor: PDZ3
Authors:Kock, G, Stoll, R.
Deposit date:2018-04-13
Release date:2018-12-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13.
J. Mol. Biol., 430, 2018
1I16
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BU of 1i16 by Molmil
STRUCTURE OF INTERLEUKIN 16: IMPLICATIONS FOR FUNCTION, NMR, 20 STRUCTURES
Descriptor: INTERLEUKIN 16
Authors:Muehlhahn, P, Zweckstetter, M, Georgescu, J, Ciosto, C, Renner, C, Lanzendoerfer, M, Lang, K, Ambrosius, D, Baier, M, Kurth, R, Holak, T.A.
Deposit date:1998-05-20
Release date:1999-05-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site.
Nat.Struct.Biol., 5, 1998
6IRE
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BU of 6ire by Molmil
Complex structure of INAD PDZ45 and NORPA CC-PBM
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein
Authors:Ye, F, Li, J, Deng, X, Liu, W, Zhang, M.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
8WWR
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BU of 8wwr by Molmil
Crystal structure of apo human dishevelled 2 (Dvl2) PDZ domain
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Omble, A, Mahajan, S, Kulkarni, K.A.
Deposit date:2023-10-26
Release date:2024-05-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
7CQF
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BU of 7cqf by Molmil
Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2020-08-10
Release date:2021-01-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention.
Proc.Natl.Acad.Sci.USA, 118, 2021
1BFE
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BU of 1bfe by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
Descriptor: PSD-95
Authors:Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
Deposit date:1998-05-20
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1B8Q
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BU of 1b8q by Molmil
SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE
Descriptor: PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE)
Authors:Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M.
Deposit date:1999-02-01
Release date:1999-04-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide.
Nat.Struct.Biol., 6, 1999
8HCK
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BU of 8hck by Molmil
NMR fragment-based screening against the two PDZ do-mains of MDA-9
Descriptor: 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, GLYCEROL, SULFATE ION, ...
Authors:Tang, H.
Deposit date:2022-11-01
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:NMR fragment-based screening against the two PDZ do-mains of MDA-9
To Be Published

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數據於2024-09-18公開中

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