3KKA
| Co-crystal structure of the sam domains of EPHA1 AND EPHA2 | Descriptor: | CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 1, EPHRIN TYPE-A RECEPTOR 2 | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Co-Crystal Structure of the SAM Domains of Human Ephrin Type-A Receptor 1 and Human Ephrin Type-A Receptor 2 To be Published
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4IS7
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1X40
| Solution structure of the SAM domain of human ARAP2 | Descriptor: | ARAP2 | Authors: | Sasagawa, A, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-12 | Release date: | 2005-11-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the SAM domain of human ARAP2 To be Published
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1B4F
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5NZ9
| NMR structure of an EphA2-Sam fragment | Descriptor: | Ephrin type-A receptor 2 | Authors: | Mercurio, F.A, Leone, M. | Deposit date: | 2017-05-12 | Release date: | 2017-12-20 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors. Sci Rep, 7, 2017
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2QKQ
| Structure of the SAM Domain of Human Ephrin Type-B Receptor 4 | Descriptor: | CHLORIDE ION, Ephrin type-B receptor 4 | Authors: | Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-07-11 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | SAM Domain of Human Ephrin Type-B Receptor 4 (EPHB4) TO BE PUBLISHED
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1F0M
| MONOMERIC STRUCTURE OF THE HUMAN EPHB2 SAM (STERILE ALPHA MOTIF) DOMAIN | Descriptor: | EPHRIN TYPE-B RECEPTOR 2 | Authors: | Thanos, C.D, Faham, S, Goodwill, K.E, Cascio, D, Phillips, M, Bowie, J.U. | Deposit date: | 2000-05-16 | Release date: | 2000-07-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Monomeric structure of the human EphB2 sterile alpha motif domain. J.Biol.Chem., 274, 1999
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2LMR
| Solution structure of the first sam domain of odin | Descriptor: | Ankyrin repeat and SAM domain-containing protein 1A | Authors: | Leone, M, Mercurio, F. | Deposit date: | 2011-12-12 | Release date: | 2012-03-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor. Biochemistry, 51, 2012
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4NJ8
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3HIL
| SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1) | Descriptor: | CHLORIDE ION, Ephrin type-A receptor 1, NITRATE ION | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-05-20 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1). To be Published
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5L1M
| CASKIN2 SAM domain tandem | Descriptor: | Caskin-2 | Authors: | Donaldson, L.W, Kwan, J.J, Saridakis, V. | Deposit date: | 2016-07-29 | Release date: | 2016-08-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.751 Å) | Cite: | A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Commun. Signal, 14, 2016
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8ATJ
| Crystal Structure of Shank2-SAM domain | Descriptor: | CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ... | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | Deposit date: | 2022-08-23 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.117 Å) | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
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8B10
| Crystal Structure of Shank2-SAM mutant domain - L1800W | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | Deposit date: | 2022-09-08 | Release date: | 2022-11-30 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 29, 2024
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5J8Y
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4NL9
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8J1I
| Crystal Structure of EphA8/SASH1 Complex | Descriptor: | Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1 | Authors: | Liu, W, Li, J, Ding, Y. | Deposit date: | 2023-04-12 | Release date: | 2024-02-28 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions. J.Mol.Biol., 435, 2023
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2MYQ
| NMR structure of an Odin-Sam1 fragment | Descriptor: | Ankyrin repeat and SAM domain-containing protein 1A | Authors: | Mercurio, F.A, Leone, M. | Deposit date: | 2015-01-30 | Release date: | 2015-07-08 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam. Chembiochem, 16, 2015
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2F3N
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1SGG
| THE SOLUTION STRUCTURE OF SAM DOMAIN FROM THE RECEPTOR TYROSINE KINASE EPHB2, NMR, 10 STRUCTURES | Descriptor: | EPHRIN TYPE-B RECEPTOR 2 | Authors: | Smalla, M, Schmieder, P, Kelly, M, Ter Laak, A, Krause, G, Ball, L, Wahl, M, Bork, P, Oschkinat, H. | Deposit date: | 1999-01-08 | Release date: | 1999-10-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites. Protein Sci., 8, 1999
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2KSO
| EphA2:SHIP2 SAM:SAM complex | Descriptor: | Ephrin type-A receptor 2, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | Authors: | Hota, P.K, Preeti, C, Stetzik, L, Kim, S, Wang, B, Lee, H, Buck, M. | Deposit date: | 2010-01-10 | Release date: | 2011-07-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and function of the EphA2:SHIP2 SAM domain heterodimer To be Published
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2KE7
| NMR structure of the first SAM domain from AIDA1 | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B | Authors: | Donaldson, L. | Deposit date: | 2009-01-27 | Release date: | 2010-02-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the first SAM domain from AIDA1 To be Published
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6FXF
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2KIV
| AIDA-1 SAM domain tandem | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B | Authors: | Donaldson, L.W, Kurabi, A. | Deposit date: | 2009-05-12 | Release date: | 2009-08-25 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import. J.Mol.Biol., 392, 2009
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6G8O
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5ZRX
| Crystal Structure of EphA2/SHIP2 Complex | Descriptor: | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | Deposit date: | 2018-04-25 | Release date: | 2018-05-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
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