7Q1L
| Glycosilated Human Serum Apo-tranferrin | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Gavira, J.A, Moreno, A, Campos-Escamilla, C, Gonzalez-Ramirez, L.A, Siliqi, D. | Deposit date: | 2021-10-20 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin. Int J Mol Sci, 22, 2021
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5X5P
| Human serum transferrin bound to ruthenium NTA | Descriptor: | FE (III) ION, MALONATE ION, NITRILOTRIACETIC ACID, ... | Authors: | Sun, H, Wang, M. | Deposit date: | 2017-02-17 | Release date: | 2018-02-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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1QJM
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8X3H
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1VFD
| HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E) | Descriptor: | CARBONATE ION, FE (III) ION, LACTOFERRIN | Authors: | Faber, H.R, Day, C.L, Baker, E.N. | Deposit date: | 1996-10-01 | Release date: | 1997-04-21 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants. Biochemistry, 35, 1996
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8FEI
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5WTD
| Structure of human serum transferrin bound ruthenium at N-lobe | Descriptor: | FE (III) ION, MALONATE ION, RUTHENIUM ION, ... | Authors: | Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q. | Deposit date: | 2016-12-11 | Release date: | 2017-12-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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8BRC
| Crystal structure of the adduct between human serum transferrin and cisplatin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIA, FE (III) ION, ... | Authors: | Troisi, R, Galardo, F, Ferraro, G, Sica, F, Merlino, A. | Deposit date: | 2022-11-22 | Release date: | 2023-01-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study. Inorg.Chem., 62, 2023
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5Y6K
| Human serum trnasferrin bound to a fluorescent probe | Descriptor: | (2S)-6-[2-(7-azido-4-methyl-2-oxidanylidene-chromen-3-yl)ethanoylamino]-2-[bis(2-hydroxy-2-oxoethyl)amino]hexanoic acid, FE (III) ION, MALONATE ION, ... | Authors: | Jiang, N, Cheng, T, Wang, M, Chan, G.C.F, Jin, L, Li, H, Sun, H. | Deposit date: | 2017-08-12 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Tracking iron-associated proteomes in pathogens by a fluorescence approach. Metallomics, 10, 2018
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6JAS
| Human serum transferrin with iron citrate bound | Descriptor: | CITRIC ACID, FE (III) ION, MALONATE ION, ... | Authors: | Wang, M, Wang, H, Sun, H. | Deposit date: | 2019-01-25 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Binding of ruthenium and osmium at non-iron sites of transferrin explains their iron-independent cellular uptake To Be Published
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7ENU
| Crystal structure of iron-saturated C-terminal half of lactoferrin produced proteolytically using pepsin at 2.32A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Singh, J, Maurya, A, Viswanathan, V, Singh, P.K, Sharma, P, Sharma, S, Singh, T.P. | Deposit date: | 2021-04-19 | Release date: | 2021-05-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.322 Å) | Cite: | Crystal structure of iron-saturated C-terminal half of lactoferrin produced proteolytically using pepsin at 2.32A resolution To Be Published
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2ZMB
| Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with parecoxib at 2.9 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Jain, R, Mir, R, Sinha, M, Singh, N, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2008-04-15 | Release date: | 2008-06-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with parecoxib at 2.9 A resolution To be Published
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1GV8
| 18 kDa fragment of N-II domain of duck ovotransferrin | Descriptor: | CARBONATE ION, FE (III) ION, GLYCINE, ... | Authors: | Kuser, P, Hall, D.R, Haw, M.L, Neu, M, Lindley, P.F. | Deposit date: | 2002-02-07 | Release date: | 2002-02-12 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Mechanism of Iron Uptake by Transferrins: The X-Ray Structures of the 18 kDa Nii Domain Fragment of Duck Ovotransferrin and its Nitrilotriacetate Complex Acta Crystallogr.,Sect.D, 58, 2002
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1GVC
| 18kDa N-II domain fragment of duck ovotransferrin + NTA | Descriptor: | CARBONATE ION, FE (III) ION, NITRILOTRIACETIC ACID, ... | Authors: | Kuser, P, Hall, D.R, Haw, M.L, Neu, M, Lindley, P.F. | Deposit date: | 2002-02-07 | Release date: | 2002-02-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Mechanism of Iron Uptake by Transferrins: The X-Ray Structures of the 18 kDa Nii Domain Fragment of Duck Ovotransferrin and its Nitrilotriacetate Complex Acta Crystallogr.,Sect.D, 58, 2002
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6WB6
| 2.05 A resolution structure of transferrin 1 from Manduca sexta | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Lovell, S, Kashipathy, M.M, Battaile, K.P, Weber, J.J, Gorman, M.J. | Deposit date: | 2020-03-26 | Release date: | 2020-11-25 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta. Protein Sci., 30, 2021
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5CRY
| Structure of iron-saturated C-lobe of bovine lactoferrin at pH 6.8 indicates the softening of iron coordination | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, FE (III) ION, ... | Authors: | Singh, A, Rastogi, N, Singh, P.K, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2015-07-23 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structure of iron-saturated C-lobe of bovine lactoferrin at pH 7.0 indicates the softening of iron coordination To Be Published
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5H52
| Structure of Titanium-bound human serum transferrin | Descriptor: | CITRIC ACID, MALONATE ION, Serotransferrin, ... | Authors: | Curtin, J.P, Wang, M, Sun, H. | Deposit date: | 2016-11-04 | Release date: | 2017-11-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The role of citrate, lactate and transferrin in determining titanium release from surgical devices into human serum. J. Biol. Inorg. Chem., 23, 2018
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4X1D
| Ytterbium-bound human serum transferrin | Descriptor: | GLYCEROL, MALONATE ION, Serotransferrin, ... | Authors: | Wang, M, Zhang, H, Sun, H. | Deposit date: | 2014-11-24 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | "Anion clamp" allows flexible protein to impose coordination geometry on metal ions Chem.Commun.(Camb.), 51, 2015
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5HBC
| Intermediate structure of iron-saturated C-lobe of bovine lactoferrin at 2.79 Angstrom resolution indicates the softening of iron coordination | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, FE (III) ION, ... | Authors: | Singh, A, Rastogi, N, Singh, P.K, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2015-12-31 | Release date: | 2016-01-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structure of iron saturated C-lobe of bovine lactoferrin at pH 6.8 indicates a weakening of iron coordination Proteins, 84, 2016
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5DYH
| Ti(IV) bound human serum transferrin | Descriptor: | CARBONATE ION, CITRIC ACID, Serotransferrin, ... | Authors: | Saxena, M, Sharma, S, Noinaj, N, Parks, T.B, Tinoco, A.D. | Deposit date: | 2015-09-24 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.682 Å) | Cite: | Unusual Synergism of Transferrin and Citrate in the Regulation of Ti(IV) Speciation, Transport, and Toxicity. J.Am.Chem.Soc., 138, 2016
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4X1B
| Human serum transferrin with ferric ion bound at the C-lobe only | Descriptor: | FE (III) ION, GLYCEROL, MALONATE ION, ... | Authors: | Wang, M, Zhang, H, Sun, H. | Deposit date: | 2014-11-24 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | "Anion clamp" allows flexible protein to impose coordination geometry on metal ions Chem.Commun.(Camb.), 51, 2015
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6XR0
| Crystal Structure of Human Melanotransferrin in complex with SC57.32 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ... | Authors: | Hayashi, K, Longenecker, K.L, Vivona, S. | Deposit date: | 2020-07-10 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.064 Å) | Cite: | Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe. Sci Rep, 11, 2021
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3O97
| Crystal Structure of the complex of C-lobe of lactoferrin with indole acetic acid at 2.68 A Resolution | Descriptor: | 1H-INDOL-3-YLACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shukla, P.K, Sinha, M, Bhushan, A, Vikram, G, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2010-08-04 | Release date: | 2010-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Crystal Structure of the complex of C-lobe of lactoferrin with indole acetic acid at 2.68 A Resolution To be Published
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3KJ7
| Crystal Structure of the Complex of C-lobe of Bovine Lactoferrin with Dextrin at 1.9 A Resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Mir, R, Vikram, G, Singh, N, Sinha, M, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2009-11-03 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Specific interactions of C-terminal half (C-lobe) of lactoferrin protein with edible sugars: binding and structural studies with implications on diabetes. Int.J.Biol.Macromol., 47, 2010
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2QJE
| Crystal structure of the complex of Bovine C-lobe with Amygdalin at 2.3A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Mir, R, Jain, R, Kumar, S, Sinha, M, Singh, N, Sharma, S, Kaur, P, Srinivasan, A, Bhushan, A, Singh, T.P. | Deposit date: | 2007-07-07 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the complex of Bovine C-lobe with Amygdalin at 2.3A resolution To be Published
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