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7T1E
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BU of 7t1e by Molmil
Structure of monomeric and dimeric human CCL20
Descriptor: C-C motif chemokine 20, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Peterson, F.C, Riutta, S.J, Volkman, B.F.
Deposit date:2021-12-01
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.459 Å)
Cite:CCL20 and CCR6 in the pathogenesis and treatment of psoriasis and psoriatic arthritis
To Be Published
5IZB
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BU of 5izb by Molmil
Murin CXCL13 solution structure featuring a folded N-terminal domain
Descriptor: C-X-C motif chemokine 13
Authors:Monneau, Y.R, Lortat-Jacob, H.
Deposit date:2016-03-25
Release date:2017-04-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Murin CXCL13 solution structure featuring a folded N-terminal domain
To be published
5YAM
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BU of 5yam by Molmil
Solution structure of mice Met-CCL5/RANTES
Descriptor: C-C motif chemokine 5
Authors:Chen, Y.-C, Chen, S.-P, Lee, Y.-Z, Sue, S.-C.
Deposit date:2017-09-01
Release date:2018-09-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
2Q8T
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BU of 2q8t by Molmil
Crystal Structure of the CC chemokine CCL14
Descriptor: CCL14
Authors:Blain, K.Y.
Deposit date:2007-06-11
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural and Functional Characterization of CC Chemokine CCL14
Biochemistry, 46, 2007
5OB5
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BU of 5ob5 by Molmil
fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
Descriptor: C-X-C motif chemokine 2, GLYCEROL, SULFATE ION, ...
Authors:Zhao, B, Ward, P, Convery, M.A.
Deposit date:2017-06-26
Release date:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery
To Be Published
6VGJ
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BU of 6vgj by Molmil
N-terminal variant of CXCL13
Descriptor: C-X-C motif chemokine 13
Authors:Rosenberg Jr, E.M, Lolis, E.J.
Deposit date:2020-01-08
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.
Acta Crystallogr D Struct Biol, 76, 2020
7JNY
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BU of 7jny by Molmil
Crystal structure of CXCL13
Descriptor: C-X-C motif chemokine 13
Authors:Rosenberg Jr, E.M, Rajasekaran, D, Murphy, J.W, Pantouris, G, Lolis, E.J.
Deposit date:2020-08-05
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.
Acta Crystallogr D Struct Biol, 76, 2020
3TN2
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BU of 3tn2 by Molmil
structure analysis of MIP1-beta P8A
Descriptor: C-C motif chemokine 4, ZINC ION
Authors:Guo, Q, Tang, W.J.
Deposit date:2011-09-01
Release date:2012-09-05
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
4DN4
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BU of 4dn4 by Molmil
Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a
Descriptor: ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ...
Authors:Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
1VMC
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BU of 1vmc by Molmil
STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA)
Descriptor: Stromal cell-derived factor 1
Authors:Gozansky, E.K, Clore, G.M.
Deposit date:2004-09-20
Release date:2005-03-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha.
J.Mol.Biol., 345, 2005
1VMP
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BU of 1vmp by Molmil
STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II
Descriptor: PROTEIN (ANTI-HIV CHEMOKINE MIP VII)
Authors:Liwang, A.C, Wang, Z.-X, Sun, Y, Peiper, S.C, Liwang, P.J.
Deposit date:1999-03-25
Release date:1999-11-24
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The solution structure of the anti-HIV chemokine vMIP-II.
Protein Sci., 8, 1999
6AEZ
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BU of 6aez by Molmil
Crystal structure of human CCL5 trimer
Descriptor: C-C motif chemokine 5, SULFATE ION
Authors:Chen, Y.C, Li, K.M, Chen, P.J, Zarivach, R, Sun, Y.J, Sue, S.C.
Deposit date:2018-08-07
Release date:2019-08-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
6SHR
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BU of 6shr by Molmil
X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A
Descriptor: Stromal cell-derived factor 1
Authors:Jugnarain, V.M, Mitchell, E, Forsyth, T, Michael, H, Cortes, S, Tillier, B.
Deposit date:2019-08-08
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.745 Å)
Cite:X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A
To Be Published
3KBX
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BU of 3kbx by Molmil
Human macrophage inflammatory protein-1 alpha L3M_V63M
Descriptor: ACETATE ION, CCL3, POTASSIUM ION
Authors:Guo, Q, Ren, M, Tang, W.-J.
Deposit date:2009-10-20
Release date:2010-10-27
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.652 Å)
Cite:Structural basis for the oligomerization of macrophage inflammatory protein-1 alpha
To be Published
2BDN
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BU of 2bdn by Molmil
Crystal structure of human MCP-1 bound to a blocking antibody, 11K2
Descriptor: Antibody heavy chain 11K2, Antibody light chain 11K2, Small inducible cytokine A2
Authors:Boriack-Sjodin, P.A, Rushe, M, Reid, C, Jarpe, M, van Vlijmen, H, Bailly, V.
Deposit date:2005-10-20
Release date:2006-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody.
Protein Eng.Des.Sel., 19, 2006
3N52
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BU of 3n52 by Molmil
crystal Structure analysis of MIP2
Descriptor: C-X-C motif chemokine 2
Authors:Rajasekaran, D.
Deposit date:2010-05-24
Release date:2011-06-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects.
Biochemistry, 51, 2012
6C6D
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BU of 6c6d by Molmil
20mer crystal structure of CC chemokine 5 (CCL5)
Descriptor: C-C motif chemokine 5
Authors:Liang, W.G, Tang, W.J.
Deposit date:2018-01-18
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:20mer crystal structure of CC chemokine 5 (CCL5)
To Be Published
6STK
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BU of 6stk by Molmil
Crystal structure of the CC-chemokine 5 (CCL5) E66S mutation
Descriptor: ACETATE ION, C-C motif chemokine 5, GLYCEROL
Authors:Ramirez-Escudero, M, Janssen, B.J.C.
Deposit date:2019-09-10
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4.
J.Biol.Chem., 295, 2020
4LMQ
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BU of 4lmq by Molmil
Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Descriptor: Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain
Authors:Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N.
Deposit date:2013-07-10
Release date:2013-08-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.773 Å)
Cite:Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12.
Clin.Cancer Res., 19, 2013
4MHE
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BU of 4mhe by Molmil
Crystal structure of CC-chemokine 18
Descriptor: ACETATE ION, C-C motif chemokine 18
Authors:Liang, W.G, Tang, W.-J.
Deposit date:2013-08-29
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
1ZXT
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BU of 1zxt by Molmil
Crystal Structure of A Viral Chemokine
Descriptor: functional macrophage inflammatory protein 1-alpha homolog
Authors:Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A.
Deposit date:2005-06-08
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
5COY
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BU of 5coy by Molmil
Crystal structure of CC chemokine 5 (CCL5)
Descriptor: C-C motif chemokine 5, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
Authors:Liang, W.G, Tang, W.
Deposit date:2015-07-20
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.443 Å)
Cite:Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
4R9W
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BU of 4r9w by Molmil
Crystal structure of platelet factor 4 complexed with fondaparinux
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Platelet factor 4
Authors:Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
Deposit date:2014-09-08
Release date:2015-12-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
Nat Commun, 6, 2015
4R9Y
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BU of 4r9y by Molmil
Crystal structure of KKOFab in complex with platelet factor 4
Descriptor: Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain
Authors:Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
Deposit date:2014-09-08
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.11 Å)
Cite:Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
Nat Commun, 6, 2015
6CWS
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BU of 6cws by Molmil
The NMR solution structure of CCL28
Descriptor: C-C motif chemokine 28
Authors:Thomas, M.A, Peterson, F.C, Volkman, B.F.
Deposit date:2018-03-30
Release date:2018-07-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Solution Structure of CCL28 Reveals Structural Lability that Does Not Constrain Antifungal Activity.
J. Mol. Biol., 430, 2018

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