6XSD
| Patient-derived B2GPI | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1 | Authors: | Klenotic, P.A, Yu, E.W.Y. | Deposit date: | 2020-07-15 | Release date: | 2021-07-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | B2-Glycoprotein I and it's role in APS To Be Published
|
|
6XST
| |
7JIK
| Human recombinant Beta-2-Glycoprotein 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, ... | Authors: | Klenotic, P.A, Yu, E.W.Y. | Deposit date: | 2020-07-23 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Beta-2-Glycoprotein I and it's role in APS To Be Published
|
|
7KG4
| Recombinant Beta-2-Glycoprotein I antibody recognition loop mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Klenotic, P.A, Yu, E.W. | Deposit date: | 2020-10-15 | Release date: | 2021-10-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Beta-2-Glycoprotein I and its role in APS To be published
|
|
3R6B
| Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3 | Descriptor: | 1,2-ETHANEDIOL, Thrombospondin-1 | Authors: | Page, R.C, Klenotic, P.A, Misra, S, Silverstein, R.L. | Deposit date: | 2011-03-21 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system. Protein Expr.Purif., 80, 2011
|
|
7SFL
| Human NKCC1 state Fu-II | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-10-04 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
7SMP
| CryoEM structure of NKCC1 Bu-I | Descriptor: | 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-10-26 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
6OR2
| MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, DODECYL-BETA-D-MALTOSIDE, Membrane protein, ... | Authors: | Su, C.-C. | Deposit date: | 2019-04-29 | Release date: | 2019-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
8STE
| Cryo-EM structure of NKCC1 Fu_CTD | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2023-05-10 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
7K8D
| |
7K8C
| |
7K8A
| |
7K8B
| |
7K7M
| Crystal Structure of a membrane protein | Descriptor: | Drug exporters of the RND superfamily-like protein, alpha-D-glucopyranose-(1-1)-6-O-decanoyl-alpha-D-glucopyranose | Authors: | Su, C.-C. | Deposit date: | 2020-09-23 | Release date: | 2021-09-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. Plos Biol., 19, 2021
|
|
7N6B
| Structure of MmpL3 reconstituted into lipid nanodisc in the TMM bound state | Descriptor: | 6-O-[(2S)-2-{(1S)-18-[(1R,2R)-2-hexylcyclopropyl]-1-hydroxyoctadecyl}tricosanoyl]-alpha-D-glucopyranosyl alpha-D-glucopyranoside, MmpL3 transporter | Authors: | Su, C.C, Yu, E. | Deposit date: | 2021-06-08 | Release date: | 2021-09-01 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. Plos Biol., 19, 2021
|
|
7MXO
| CryoEM structure of human NKCC1 | Descriptor: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-05-19 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
7N3N
| CryoEM structure of human NKCC1 state Fu-I | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | Authors: | Moseng, M.A. | Deposit date: | 2021-06-01 | Release date: | 2022-09-28 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|