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1II6
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BU of 1ii6 by Molmil
Crystal Structure of the Mitotic Kinesin Eg5 in Complex with Mg-ADP.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KINESIN-RELATED MOTOR PROTEIN Eg5, MAGNESIUM ION, ...
Authors:Turner, J, Anderson, R, Guo, J, Beraud, C, Sakowicz, R, Fletterick, R.
Deposit date:2001-04-20
Release date:2001-07-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker.
J.Biol.Chem., 276, 2001
1RY6
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BU of 1ry6 by Molmil
Crystal Structure of Internal Kinesin Motor Domain
Descriptor: INTERNAL KINESIN, SULFATE ION
Authors:Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R.
Deposit date:2003-12-19
Release date:2004-04-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a kinesin microtubule depolymerization machine.
Embo J., 23, 2004
1MKJ
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BU of 1mkj by Molmil
Human Kinesin Motor Domain With Docked Neck Linker
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ...
Authors:Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R.
Deposit date:2002-08-29
Release date:2002-10-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
Nat.Struct.Biol., 9, 2002
1AIM
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BU of 1aim by Molmil
CRUZAIN INHIBITED BY BENZOYL-TYROSINE-ALANINE-FLUOROMETHYLKETONE
Descriptor: BENZOYL-TYROSINE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
Authors:Fletterick, R, Gillmor, S.
Deposit date:1997-04-21
Release date:1997-10-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
2QPY
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BU of 2qpy by Molmil
AR LBD with small molecule
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Coactivator peptide, ...
Authors:Estebanez-Perpina, E, Fletterick, R.
Deposit date:2007-07-25
Release date:2007-09-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1PYG
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BU of 1pyg by Molmil
STRUCTURAL BASIS FOR THE ACTIVATION OF GLYCOGEN PHOSPHORYLASE B BY ADENOSINE MONOPHOSPHATE
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-DIPHOSPHATE
Authors:Sprang, S.
Deposit date:1992-07-07
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate.
Science, 254, 1991
1LOX
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BU of 1lox by Molmil
RABBIT RETICULOCYTE 15-LIPOXYGENASE
Descriptor: (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID, 15-LIPOXYGENASE, FE (II) ION
Authors:Gillmor, S.A, Villasenor, A, Fletterick, R.J, Sigal, E, Browner, M.F.
Deposit date:1997-10-06
Release date:1998-11-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.
Nat.Struct.Biol., 4, 1997
3TX7
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BU of 3tx7 by Molmil
Crystal structure of LRH-1/beta-catenin complex
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Catenin beta-1, Nuclear receptor subfamily 5 group A member 2
Authors:Yumoto, F, Fletterick, R.
Deposit date:2011-09-22
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural basis of coactivation of liver receptor homolog-1 by beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3BKI
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BU of 3bki by Molmil
Crystal Structure of the GluR2 ligand binding core (S1S2J) in complex with FQX at 1.87 Angstroms
Descriptor: Glutamate receptor 2, [1,2,5]oxadiazolo[3,4-g]quinoxaline-6,7(5H,8H)-dione 1-oxide
Authors:Cruz, L, Estebanez-Perpina, E, Pfaff, S, Borngraeber, S, Bao, N, Fletterick, R, England, P.
Deposit date:2007-12-06
Release date:2008-09-16
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor.
J.Med.Chem., 51, 2008
1FI8
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BU of 1fi8 by Molmil
RAT GRANZYME B [N66Q] COMPLEXED TO ECOTIN [81-84 IEPD]
Descriptor: ECOTIN, NATURAL KILLER CELL PROTEASE 1
Authors:Waugh, S.M, Harris, J.L, Fletterick, R.J, Craik, C.S.
Deposit date:2000-08-03
Release date:2000-09-13
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity
Nat.Struct.Biol., 7, 2000
2P0M
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BU of 2p0m by Molmil
Revised structure of rabbit reticulocyte 15S-lipoxygenase
Descriptor: (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID, Arachidonate 15-lipoxygenase, FE (II) ION
Authors:Choi, J, Chon, J.K, Kim, S, Shin, W.
Deposit date:2007-02-28
Release date:2007-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data.
Proteins, 70, 2008

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