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4HEA
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BU of 4hea by Molmil
Crystal structure of the entire respiratory complex I from Thermus thermophilus
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Baradaran, R, Berrisford, J.M, Minhas, G.S, Sazanov, L.A.
Deposit date:2012-10-03
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3027 Å)
Cite:Crystal structure of the entire respiratory complex I.
Nature, 494, 2013
4HE8
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BU of 4he8 by Molmil
Crystal structure of the membrane domain of respiratory complex I from Thermus thermophilus
Descriptor: NADH-quinone oxidoreductase subunit 10, NADH-quinone oxidoreductase subunit 11, NADH-quinone oxidoreductase subunit 12, ...
Authors:Baradaran, R, Berrisford, J.M, Minhas, G.S, Sazanov, L.A.
Deposit date:2012-10-03
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the entire respiratory complex I.
Nature, 494, 2013
6DNF
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BU of 6dnf by Molmil
Cryo-EM structure of the mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea
Descriptor: 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, CALCIUM ION, Mitochondrial calcium uniporter MCU
Authors:Long, S.B, Baradaran, R, Wang, C.
Deposit date:2018-06-06
Release date:2018-07-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters.
Nature, 559, 2018
7AOI
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BU of 7aoi by Molmil
Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ...
Authors:Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A.
Deposit date:2020-10-14
Release date:2020-12-02
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
8B6G
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BU of 8b6g by Molmil
Cryo-EM structure of succinate dehydrogenase complex (complex-II) in respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
6X4S
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BU of 6x4s by Molmil
MCU-EMRE complex of a metazoan mitochondrial calcium uniporter
Descriptor: CALCIUM ION, Calcium uniporter protein,Protein EMRE homolog, mitochondrial-like Protein fusion
Authors:Long, S.B, Wang, C, Baradaran, R.
Deposit date:2020-05-22
Release date:2020-09-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure and Reconstitution of an MCU-EMRE Mitochondrial Ca 2+ Uniporter Complex.
J.Mol.Biol., 432, 2020
6XQN
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BU of 6xqn by Molmil
Structure of a mitochondrial calcium uniporter holocomplex (MICU1, MICU2, MCU, EMRE) in low Ca2+
Descriptor: CALCIUM ION, Calcium uniporter protein, Calcium uptake protein 1, ...
Authors:Long, S.B, Wang, C, Baradaran, R, Jacewicz, A, Delgado, B.
Deposit date:2020-07-09
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures reveal gatekeeping of the mitochondrial Ca 2+ uniporter by MICU1-MICU2.
Elife, 9, 2020
6XQO
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BU of 6xqo by Molmil
Structure of the human MICU1-MICU2 heterodimer, calcium bound, in association with a lipid nanodisc
Descriptor: CALCIUM ION, Calcium uptake protein 1, mitochondrial, ...
Authors:Long, S.B, Wang, C, Baradaran, R, Jacewicz, A, Delgado, B.
Deposit date:2020-07-09
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures reveal gatekeeping of the mitochondrial Ca 2+ uniporter by MICU1-MICU2.
Elife, 9, 2020
8BQS
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BU of 8bqs by Molmil
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-11-21
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
3M9C
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BU of 3m9c by Molmil
Crystal structure of the membrane domain of respiratory complex I from Escherichia coli
Descriptor: NADH-quinone oxidoreductase subunit NuoL, NADH-quinone oxidoreductase subunit NuoM, NADH-quinone oxidoreductase subunit NuoN, ...
Authors:Efremov, R.G, Baradaran, R, Sazanov, L.A.
Deposit date:2010-03-22
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:The architecture of respiratory complex I
Nature, 465, 2010
3M9S
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BU of 3m9s by Molmil
Crystal structure of respiratory complex I from Thermus thermophilus
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Efremov, R.G, Baradaran, R, Sazanov, L.A.
Deposit date:2010-03-22
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The architecture of respiratory complex I
Nature, 465, 2010
7PGT
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BU of 7pgt by Molmil
The structure of human neurofibromin isoform 2 in opened conformation.
Descriptor: Neurofibromin, ZINC ION
Authors:Naschberger, A, Baradaran, R, Carroni, M, Rupp, B.
Deposit date:2021-08-15
Release date:2021-11-17
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
7PGR
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BU of 7pgr by Molmil
The structure of human neurofibromin isoform 2 in closed conformation
Descriptor: Neurofibromin, ZINC ION
Authors:Naschberger, A, Baradaran, R, Carroni, M, Rupp, B.
Deposit date:2021-08-15
Release date:2021-11-17
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
7PGS
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BU of 7pgs by Molmil
Consensus structure of human Neurofibromin isoform 2
Descriptor: Neurofibromin, ZINC ION
Authors:Naschberger, A, Baradaran, R, Carroni, M, Rupp, B.
Deposit date:2021-08-15
Release date:2021-11-17
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
7PGU
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BU of 7pgu by Molmil
Autoinhibited structure of human neurofibromin isoform 2 stabilized by Zinc.
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION
Authors:Naschberger, A, Baradaran, R, Carroni, M, Rupp, B.
Deposit date:2021-08-15
Release date:2021-11-17
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
7PGP
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BU of 7pgp by Molmil
The core structure of human neurofibromin isoform 2
Descriptor: Neurofibromin
Authors:Naschberger, A, Baradaran, R, Carroni, M, Rupp, B.
Deposit date:2021-08-15
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
7PGQ
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BU of 7pgq by Molmil
GAP-SecPH region of human neurofibromin isoform 2 in closed conformation.
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION
Authors:Naschberger, A, Baradaran, R, Carroni, M, Rupp, B.
Deposit date:2021-08-15
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
8B6F
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BU of 8b6f by Molmil
Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
8B6H
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BU of 8b6h by Molmil
Cryo-EM structure of cytochrome c oxidase dimer (complex IV) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
8B6J
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BU of 8b6j by Molmil
Cryo-EM structure of cytochrome bc1 complex (complex-III) from respiratory supercomplex of Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apocytochrome b, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2022-09-27
Release date:2023-03-29
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
6I0D
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BU of 6i0d by Molmil
Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiquinone
Descriptor: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
Deposit date:2018-10-25
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
6I1P
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BU of 6i1p by Molmil
Respiratory complex I from Thermus thermophilus with bound NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
Deposit date:2018-10-29
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.207 Å)
Cite:Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
6Q8X
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BU of 6q8x by Molmil
Respiratory complex I from Thermus thermophilus with bound Pyridaben.
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
Deposit date:2018-12-16
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.508 Å)
Cite:Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
6Q8W
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BU of 6q8w by Molmil
Respiratory complex I from Thermus thermophilus with bound Aureothin.
Descriptor: Aureothin, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
Deposit date:2018-12-16
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
6Q8O
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BU of 6q8o by Molmil
Respiratory complex I from Thermus thermophilus with bound Piericidin A
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
Deposit date:2018-12-15
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.605 Å)
Cite:Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020

 

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