Entry Database : PDB / ID : 4x38 Structure visualization Downloads & linksTitle Gallus interleukin-1 beta mutant - E118A ComponentsIL-1 beta Details Keywords IMMUNE SYSTEMFunction / homology Function and homology informationFunction Domain/homology Component
chemokine production / Interleukin-1 processing / Pyroptosis / Interleukin-1 signaling / cortisol secretion / leukocyte activation involved in inflammatory response / leukocyte chemotaxis involved in inflammatory response / detection of lipopolysaccharide / regulation of non-canonical NF-kappaB signal transduction / sexual reproduction ... chemokine production / Interleukin-1 processing / Pyroptosis / Interleukin-1 signaling / cortisol secretion / leukocyte activation involved in inflammatory response / leukocyte chemotaxis involved in inflammatory response / detection of lipopolysaccharide / regulation of non-canonical NF-kappaB signal transduction / sexual reproduction / positive regulation of immature T cell proliferation in thymus / neutrophil activation / fever generation / interleukin-1 receptor binding / inflammatory response to antigenic stimulus / cellular response to cold / toll-like receptor signaling pathway / macrophage chemotaxis / cytokine activity / acute-phase response / response to virus / cytokine-mediated signaling pathway / positive regulation of inflammatory response / cellular response to lipopolysaccharide / lysosome / inflammatory response / positive regulation of gene expression / extracellular space / cytosol Similarity search - Function Interleukin-1 conserved site / Interleukin-1 signature. / Interleukin-1 homologues / Interleukin-1 family / Interleukin-1 / 18 / Cytokine IL1/FGF / Trefoil (Acidic Fibroblast Growth Factor, subunit A) - #50 / Trefoil (Acidic Fibroblast Growth Factor, subunit A) / Trefoil / Mainly Beta Similarity search - Domain/homologyBiological species Gallus gallus (chicken)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.12 Å DetailsAuthors Yin, H.S. / Cheng, W.T. Funding support Taiwan, 1items Details Hide detailsOrganization Grant number Country Ministry of Science and Technology 103-2311-B-007 -003 -MY3 Taiwan
CitationJournal : To Be Published Title : Gallus interleukin-1 beta mutant - E118AAuthors : Yin, H.S. / Cheng, W.T. History Deposition Nov 28, 2014 Deposition site : RCSB / Processing site : PDBJRevision 1.0 Dec 9, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Nov 8, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_oper_list Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation
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