Entry Database : PDB / ID : 2ylf Structure visualization Downloads & linksTitle Crystal structure of the human Spir-1 KIND domain ComponentsPROTEIN SPIRE HOMOLOG 1 Details Keywords ACTIN-BINDING PROTEIN / ACTIN POLYMERIZATION / SPIR / KINASEFunction / homology Function and homology informationFunction Domain/homology Component
formin-nucleated actin cable assembly / establishment of meiotic spindle localization / polar body extrusion after meiotic divisions / actin filament network formation / actin nucleation / Golgi vesicle transport / cleavage furrow formation / positive regulation of double-strand break repair / positive regulation of mitochondrial fission / intracellular transport ... formin-nucleated actin cable assembly / establishment of meiotic spindle localization / polar body extrusion after meiotic divisions / actin filament network formation / actin nucleation / Golgi vesicle transport / cleavage furrow formation / positive regulation of double-strand break repair / positive regulation of mitochondrial fission / intracellular transport / vesicle-mediated transport / actin filament polymerization / cytoplasmic vesicle membrane / protein transport / actin binding / cell cortex / actin cytoskeleton organization / microtubule binding / mitochondrial outer membrane / cytoskeleton / innate immune response / perinuclear region of cytoplasm / nucleoplasm / plasma membrane / cytosol Similarity search - Function Protein Spire1 / Protein Spire / Kinase non-catalytic C-lobe domain / KIND domain / KIND domain profile. / kinase non-catalytic C-lobe domain / Zinc finger, FYVE/PHD-type / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.05 Å DetailsAuthors Zeth, K. / Pechlivanis, M. / Vonrhein, C. / Kerkhoff, E. CitationJournal : J.Biol.Chem. / Year : 2011Title : Molecular Basis of Actin Nucleation Factor Cooperativity: Crystal Structure of the Spir-1 Kinase Non-Catalytic C-Lobe Domain (Kind)Formin-2 Formin Spir Interaction Motif (Fsi) Complex.Authors : Zeth, K. / Pechlivanis, M. / Samol, A. / Pleiser, S. / Vonrhein, C. / Kerkhoff, E. History Deposition Jun 1, 2011 Deposition site : PDBE / Processing site : PDBERevision 1.0 Jun 8, 2011 Provider : repository / Type : Initial releaseRevision 1.1 Aug 15, 2012 Group : Database references / Version format complianceRevision 1.2 Aug 23, 2017 Group : Data collection / Category : diffrn_detector / Item : _diffrn_detector.typeRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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