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Yorodumi- PDB-2okj: The X-ray crystal structure of the 67kDa isoform of Glutamic Acid... -
+Open data
-Basic information
Entry | Database: PDB / ID: 2okj | |||||||||
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Title | The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) | |||||||||
Components | Glutamate decarboxylase 1 | |||||||||
Keywords | LYASE / PLP-dependent decarboxylase | |||||||||
Function / homology | Function and homology information GABA synthesis / gamma-aminobutyrate shunt / MECP2 regulates transcription of genes involved in GABA signaling / glutamate decarboxylase / glutamate decarboxylase activity / gamma-aminobutyric acid biosynthetic process / clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane / GABA synthesis, release, reuptake and degradation / inhibitory synapse / glutamate catabolic process ...GABA synthesis / gamma-aminobutyrate shunt / MECP2 regulates transcription of genes involved in GABA signaling / glutamate decarboxylase / glutamate decarboxylase activity / gamma-aminobutyric acid biosynthetic process / clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane / GABA synthesis, release, reuptake and degradation / inhibitory synapse / glutamate catabolic process / vesicle membrane / locomotory exploration behavior / presynaptic active zone / social behavior / GABA-ergic synapse / axon terminus / pyridoxal phosphate binding / cell cortex / chemical synaptic transmission / identical protein binding / plasma membrane / cytoplasm Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.3 Å | |||||||||
Authors | Buckle, A.M. / Fenalti, G. / Law, R.H.P. / Whisstock, J.C. | |||||||||
Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2007 Title: GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Authors: Fenalti, G. / Law, R.H.P. / Buckle, A.M. / Langendorf, C. / Tuck, K. / Rosado, C.J. / Faux, N.G. / Mahmood, K. / Hampe, C.S. / Banga, J.P. / Wilce, M. / Schmidberger, J. / Rossjohn, J. / El- ...Authors: Fenalti, G. / Law, R.H.P. / Buckle, A.M. / Langendorf, C. / Tuck, K. / Rosado, C.J. / Faux, N.G. / Mahmood, K. / Hampe, C.S. / Banga, J.P. / Wilce, M. / Schmidberger, J. / Rossjohn, J. / El-Kabbani, O. / Pike, R.N. / Smith, A.I. / Mackay, I.R. / Rowley, M.J. / Whisstock, J.C. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2okj.cif.gz | 219.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2okj.ent.gz | 171.1 KB | Display | PDB format |
PDBx/mmJSON format | 2okj.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 2okj_validation.pdf.gz | 468.8 KB | Display | wwPDB validaton report |
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Full document | 2okj_full_validation.pdf.gz | 481.2 KB | Display | |
Data in XML | 2okj_validation.xml.gz | 40 KB | Display | |
Data in CIF | 2okj_validation.cif.gz | 56.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ok/2okj ftp://data.pdbj.org/pub/pdb/validation_reports/ok/2okj | HTTPS FTP |
-Related structure data
Related structure data | 2okkC 1js3S C: citing same article (ref.) S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Component-ID: 1
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