+Open data
-Basic information
Entry | Database: PDB / ID: 1qwf | ||||||
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Title | C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND VSL12 | ||||||
Components |
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Keywords | COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) / SRC SH3 DOMAIN / CLASS I LIGAND COMPLEX / COMPLEX (SIGNAL TRANSDUCTION-PEPTIDE) COMPLEX | ||||||
Function / homology | Function and homology information non-specific protein-tyrosine kinase / non-membrane spanning protein tyrosine kinase activity / phosphorylation / ATP binding Similarity search - Function | ||||||
Biological species | Avian sarcoma virus | ||||||
Method | SOLUTION NMR | ||||||
Authors | Feng, S. / Chiyoshi, K. / Rickles, R.J. / Schreiber, S.L. | ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 1995 Title: Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Authors: Feng, S. / Kasahara, C. / Rickles, R.J. / Schreiber, S.L. #1: Journal: Cell(Cambridge,Mass.) / Year: 1994 Title: Structural Basis for the Binding of Proline-Rich Peptides to SH3 Domains Authors: Yu, H. / Chen, J.K. / Feng, S. / Dalgarno, D.C. / Brauer, A.W. / Schreiber, S.L. #2: Journal: Science / Year: 1994 Title: Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions Authors: Feng, S. / Chen, J.K. / Yu, H. / Simon, J.A. / Schreiber, S.L. #3: Journal: Science / Year: 1992 Title: Solution Structure of the SH3 Domain of Src and Identification of its Ligand-Binding Site Authors: Yu, H. / Rosen, M.K. / Shin, T.B. / Seidel-Dugan, C. / Brugge, J.S. / Schreiber, S.L. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1qwf.cif.gz | 30.1 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1qwf.ent.gz | 23.2 KB | Display | PDB format |
PDBx/mmJSON format | 1qwf.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/qw/1qwf ftp://data.pdbj.org/pub/pdb/validation_reports/qw/1qwf | HTTPS FTP |
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-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 7104.749 Da / Num. of mol.: 1 / Fragment: SH3 DOMAIN Source method: isolated from a genetically manipulated source Source: (gene. exp.) Avian sarcoma virus / Genus: Alpharetrovirus / Description: GST-FUSION / Gene: CHICKEN / Plasmid: PGEX-2T / Gene (production host): CHICKEN / Production host: Escherichia coli (E. coli) / References: UniProt: P00525, EC: 2.7.1.112 |
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#2: Protein/peptide | Mass: 1317.622 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other |
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-Processing
Software |
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NMR software | Name: X-PLOR / Version: 3.1 / Developer: BRUNGER / Classification: refinement | ||||||||||||
NMR ensemble | Conformers submitted total number: 1 |