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Yorodumi- PDB-1cfh: STRUCTURE OF THE METAL-FREE GAMMA-CARBOXYGLUTAMIC ACID-RICH MEMBR... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1cfh | ||||||
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Title | STRUCTURE OF THE METAL-FREE GAMMA-CARBOXYGLUTAMIC ACID-RICH MEMBRANE BINDING REGION OF FACTOR IX BY TWO-DIMENSIONAL NMR SPECTROSCOPY | ||||||
Components | COAGULATION FACTOR IX | ||||||
Keywords | COAGULATION FACTOR | ||||||
Function / homology | Function and homology information Defective F9 secretion / Defective gamma-carboxylation of F9 / coagulation factor IXa / Defective F9 activation / Defective factor IX causes thrombophilia / Defective cofactor function of FVIIIa variant / Defective F9 variant does not activate FX / zymogen activation / Extrinsic Pathway of Fibrin Clot Formation / Protein hydroxylation ...Defective F9 secretion / Defective gamma-carboxylation of F9 / coagulation factor IXa / Defective F9 activation / Defective factor IX causes thrombophilia / Defective cofactor function of FVIIIa variant / Defective F9 variant does not activate FX / zymogen activation / Extrinsic Pathway of Fibrin Clot Formation / Protein hydroxylation / Gamma-carboxylation of protein precursors / Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus / Removal of aminoterminal propeptides from gamma-carboxylated proteins / Intrinsic Pathway of Fibrin Clot Formation / Golgi lumen / blood coagulation / endopeptidase activity / collagen-containing extracellular matrix / endoplasmic reticulum lumen / serine-type endopeptidase activity / calcium ion binding / proteolysis / extracellular space / extracellular exosome / extracellular region / metal ion binding / plasma membrane Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Freedman, S.J. / Furie, B.C. / Furie, B. / Baleja, J.D. | ||||||
Citation | Journal: J.Biol.Chem. / Year: 1995 Title: Structure of the metal-free gamma-carboxyglutamic acid-rich membrane binding region of factor IX by two-dimensional NMR spectroscopy. Authors: Freedman, S.J. / Furie, B.C. / Furie, B. / Baleja, J.D. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1cfh.cif.gz | 139.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1cfh.ent.gz | 115.2 KB | Display | PDB format |
PDBx/mmJSON format | 1cfh.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1cfh_validation.pdf.gz | 374.2 KB | Display | wwPDB validaton report |
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Full document | 1cfh_full_validation.pdf.gz | 475.2 KB | Display | |
Data in XML | 1cfh_validation.xml.gz | 17.8 KB | Display | |
Data in CIF | 1cfh_validation.cif.gz | 30 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/cf/1cfh ftp://data.pdbj.org/pub/pdb/validation_reports/cf/1cfh | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 5765.246 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / References: UniProt: P00740 |
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#2: Chemical | ChemComp-FMT / |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other |
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-Processing
NMR software | Name: DGII / Developer: BIOSYM TECHNOLOGIES INC. / Classification: refinement |
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NMR ensemble | Conformers submitted total number: 15 |