DNA BINDING PROTEIN (DNA結合タンパク質) / 8-OXO-2P-DEOXY-GUANOSINE-5P-MONOPHOSPHATE / TRANSLESION DNA POLYMERASE / HUMAN DNA POLYMERASE KAPPA / DATP (デオキシアデノシン三リン酸) / DNA REPAIR (DNA修復) / DNA DAMAGE (DNA修復) / DNA-BINDING PROTEIN (DNA結合タンパク質)
機能・相同性
機能・相同性情報
nucleotide-excision repair, DNA gap filling / error-prone translesion synthesis / Translesion synthesis by POLK / Gap-filling DNA repair synthesis and ligation in GG-NER / Termination of translesion DNA synthesis / HDR through Homologous Recombination (HRR) / Dual Incision in GG-NER / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / cellular response to UV ...nucleotide-excision repair, DNA gap filling / error-prone translesion synthesis / Translesion synthesis by POLK / Gap-filling DNA repair synthesis and ligation in GG-NER / Termination of translesion DNA synthesis / HDR through Homologous Recombination (HRR) / Dual Incision in GG-NER / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / cellular response to UV / DNA複製 / damaged DNA binding / DNAポリメラーゼ / DNA-directed DNA polymerase activity / nuclear body / DNA修復 / DNA damage response / 核質 / metal ion binding / 細胞核 類似検索 - 分子機能
DNA polymerase; domain 1 - #810 / Rad18-like CCHC zinc finger / DNA polymerase type-Y, HhH motif / IMS family HHH motif / DNA polymerase IV / DNA polymerase, Y-family, little finger domain / MutS, DNA mismatch repair protein, domain I - #60 / Rad18, zinc finger UBZ4-type / Zinc finger UBZ4-type profile. / MutS, DNA mismatch repair protein, domain I ...DNA polymerase; domain 1 - #810 / Rad18-like CCHC zinc finger / DNA polymerase type-Y, HhH motif / IMS family HHH motif / DNA polymerase IV / DNA polymerase, Y-family, little finger domain / MutS, DNA mismatch repair protein, domain I - #60 / Rad18, zinc finger UBZ4-type / Zinc finger UBZ4-type profile. / MutS, DNA mismatch repair protein, domain I / DNA polymerase, Y-family, little finger domain / impB/mucB/samB family C-terminal domain / UmuC domain / DNA polymerase, Y-family, little finger domain superfamily / impB/mucB/samB family / UmuC domain profile. / Reverse transcriptase/Diguanylate cyclase domain / Dna Ligase; domain 1 / DNA polymerase; domain 1 / Reverse transcriptase/Diguanylate cyclase domain / Alpha-Beta Plaits / DNA/RNA polymerase superfamily / 2-Layer Sandwich / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE / デオキシリボ核酸 / DNA (> 10) / DNA polymerase kappa 類似検索 - 構成要素
pH: 7 詳細: 70 MM NACL,1.35 MM KCL, 2.1 MM NA2HPO4, 0.75 MM KH2PO4, PH 7.4, 5 MM GLYCEROL, 0.5 MM EDTA, 0.5 MM DTT, 2.5 MM 2-MERCHAPTOETHANOL, 0.05% NONIDET P-40, 2.5 MM CACL2, 2.5 MM DATP, 11% ...詳細: 70 MM NACL,1.35 MM KCL, 2.1 MM NA2HPO4, 0.75 MM KH2PO4, PH 7.4, 5 MM GLYCEROL, 0.5 MM EDTA, 0.5 MM DTT, 2.5 MM 2-MERCHAPTOETHANOL, 0.05% NONIDET P-40, 2.5 MM CACL2, 2.5 MM DATP, 11% PEG5000MME, 0.1 M AMMONIUM ACETATE,10 MM MES PH 6.5
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データ収集
回折
平均測定温度: 110 K
放射光源
由来: シンクロトロン / サイト: APS / ビームライン: 21-ID-F / 波長: 1
検出器
タイプ: MARRESEARCH / 検出器: CCD / 日付: 2007年10月20日
放射
モノクロメーター: DIAMOND 111 / プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長
波長: 1 Å / 相対比: 1
反射
解像度: 3.71→44.65 Å / Num. obs: 23041 / % possible obs: 96.9 % / Observed criterion σ(I): 0 / 冗長度: 5.4 % / Biso Wilson estimate: 62.5 Å2 / Rmerge(I) obs: 0.15 / Net I/σ(I): 10.4
反射 シェル
解像度: 3.7→3.93 Å / 冗長度: 5.5 % / Rmerge(I) obs: 0.62 / Mean I/σ(I) obs: 2.9 / % possible all: 86.4