登録情報 データベース : PDB / ID : 2pld 構造の表示 ダウンロードとリンクタイトル NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 要素PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN PHOSPHOPEPTIDE FROM PDGF 詳細キーワード PHOSPHORIC DIESTER HYDROLASE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
platelet activating factor receptor activity / platelet-derived growth factor receptor activity / platelet-derived growth factor beta-receptor activity / cell migration involved in coronary angiogenesis / metanephric glomerular mesangial cell proliferation involved in metanephros development / positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway / smooth muscle cell chemotaxis / calcium-dependent phospholipase C activity / metanephric glomerular capillary formation / cell migration involved in vasculogenesis ... platelet activating factor receptor activity / platelet-derived growth factor receptor activity / platelet-derived growth factor beta-receptor activity / cell migration involved in coronary angiogenesis / metanephric glomerular mesangial cell proliferation involved in metanephros development / positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway / smooth muscle cell chemotaxis / calcium-dependent phospholipase C activity / metanephric glomerular capillary formation / cell migration involved in vasculogenesis / aorta morphogenesis / phosphoinositide phospholipase C / positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway / platelet-derived growth factor binding / phospholipid catabolic process / vascular endothelial growth factor binding / retina vasculature development in camera-type eye / cardiac myofibril assembly / phosphatidylinositol metabolic process / Signaling by PDGF / positive regulation of chemotaxis / phosphatidylinositol phospholipase C activity / COP9 signalosome / platelet-derived growth factor receptor binding / positive regulation of DNA biosynthetic process / positive regulation of epithelial cell migration / positive regulation of smooth muscle cell migration / positive regulation of calcium ion import / platelet-derived growth factor receptor-beta signaling pathway / phosphatidylinositol-mediated signaling / : / platelet-derived growth factor receptor signaling pathway / cellular response to epidermal growth factor stimulus / cellular response to vascular endothelial growth factor stimulus / : / release of sequestered calcium ion into cytosol / ruffle / positive regulation of calcium-mediated signaling / Downstream signal transduction / positive regulation of mitotic nuclear division / lysosomal lumen / positive regulation of smooth muscle cell proliferation / cell chemotaxis / positive regulation of MAP kinase activity / guanyl-nucleotide exchange factor activity / epidermal growth factor receptor signaling pathway / receptor protein-tyrosine kinase / regulation of actin cytoskeleton organization / ruffle membrane / peptidyl-tyrosine phosphorylation / Constitutive Signaling by Aberrant PI3K in Cancer / positive regulation of reactive oxygen species metabolic process / PIP3 activates AKT signaling / lamellipodium / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / RAF/MAP kinase cascade / protein tyrosine kinase activity / cytoplasmic vesicle / protein autophosphorylation / in utero embryonic development / receptor complex / positive regulation of ERK1 and ERK2 cascade / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / positive regulation of cell migration / protein kinase activity / apical plasma membrane / intracellular membrane-bounded organelle / focal adhesion / signaling receptor binding / positive regulation of cell population proliferation / calcium ion binding / protein kinase binding / enzyme binding / Golgi apparatus / signal transduction / ATP binding / membrane / nucleus / plasma membrane / cytoplasm 類似検索 - 分子機能 Platelet-derived growth factor receptor beta / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain / Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma / PLC-gamma, C-terminal SH2 domain / PLC-gamma, N-terminal SH2 domain / Phosphoinositide phospholipase C family / Phospholipase C, phosphatidylinositol-specific, Y domain / Phosphatidylinositol-specific phospholipase C, Y domain / Phosphatidylinositol-specific phospholipase Y-box domain profile. / Phospholipase C, catalytic domain (part); domain Y ... Platelet-derived growth factor receptor beta / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain / Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma / PLC-gamma, C-terminal SH2 domain / PLC-gamma, N-terminal SH2 domain / Phosphoinositide phospholipase C family / Phospholipase C, phosphatidylinositol-specific, Y domain / Phosphatidylinositol-specific phospholipase C, Y domain / Phosphatidylinositol-specific phospholipase Y-box domain profile. / Phospholipase C, catalytic domain (part); domain Y / Phosphatidylinositol-specific phospholipase C, X domain / Phosphatidylinositol-specific phospholipase C, X domain / Phospholipase C, catalytic domain (part); domain X / Phosphatidylinositol-specific phospholipase X-box domain profile. / PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily / Tyrosine-protein kinase, receptor class III, conserved site / Receptor tyrosine kinase class III signature. / SH2 domain / SHC Adaptor Protein / C2 domain / Protein kinase C conserved region 2 (CalB) / C2 domain / C2 domain profile. / Immunoglobulin / Immunoglobulin domain / Immunoglobulin domain / : / PH domain / C2 domain superfamily / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / SH3 domain / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH2 domain / EF-Hand 1, calcium-binding site / Src homology 3 domains / EF-hand calcium-binding domain. / SH2 domain superfamily / EF-hand calcium-binding domain profile. / SH3-like domain superfamily / EF-hand domain / Src homology 3 (SH3) domain profile. / SH3 domain / EF-hand domain pair / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / Tyrosine-protein kinase, active site / Immunoglobulin subtype / Immunoglobulin / PH-like domain superfamily / Serine-threonine/tyrosine-protein kinase, catalytic domain / Protein tyrosine and serine/threonine kinase / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Immunoglobulin-like fold / Protein kinase-like domain superfamily / 2-Layer Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 / Platelet-derived growth factor receptor beta 類似検索 - 構成要素生物種 Bos taurus (ウシ)手法 溶液NMR 詳細データ登録者 Pascal, S.M. / Singer, A.U. / Gish, G. / Yamazaki, T. / Shoelson, S.E. / Pawson, T. / Kay, L.E. / Forman-Kay, J.D. 引用ジャーナル : Cell(Cambridge,Mass.) / 年 : 1994タイトル : Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.著者 : Pascal, S.M. / Singer, A.U. / Gish, G. / Yamazaki, T. / Shoelson, S.E. / Pawson, T. / Kay, L.E. / Forman-Kay, J.D. 履歴 登録 1994年8月19日 処理サイト : BNL改定 1.0 1995年1月26日 Provider : repository / タイプ : Initial release改定 1.1 2008年3月3日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2017年11月29日 Group : Derived calculations / Otherカテゴリ : pdbx_database_status / pdbx_struct_assembly ... pdbx_database_status / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conf / struct_conf_type Item : _pdbx_database_status.process_site
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