- PDB-2alu: Detection of new binding site in the C-terminal lobe of lactoferr... -
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基本情報
登録情報
データベース: PDB / ID: 2alu
タイトル
Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution
要素
Lactotransferrinラクトフェリン
キーワード
TRANSPORT PROTEIN (運搬体タンパク質) / lactoferrin (ラクトフェリン) / complex
機能・相同性
機能・相同性情報
Metal sequestration by antimicrobial proteins / 抗微生物ペプチド / negative regulation of cysteine-type endopeptidase activity / negative regulation of tumor necrosis factor (ligand) superfamily member 11 production / negative regulation of single-species biofilm formation in or on host organism / positive regulation of bone mineralization involved in bone maturation / negative regulation of lipopolysaccharide-mediated signaling pathway / specific granule / negative regulation of osteoclast development / antifungal humoral response ...Metal sequestration by antimicrobial proteins / 抗微生物ペプチド / negative regulation of cysteine-type endopeptidase activity / negative regulation of tumor necrosis factor (ligand) superfamily member 11 production / negative regulation of single-species biofilm formation in or on host organism / positive regulation of bone mineralization involved in bone maturation / negative regulation of lipopolysaccharide-mediated signaling pathway / specific granule / negative regulation of osteoclast development / antifungal humoral response / positive regulation of chondrocyte proliferation / regulation of tumor necrosis factor production / bone morphogenesis / Neutrophil degranulation / cysteine-type endopeptidase inhibitor activity / positive regulation of osteoblast proliferation / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; セリンエンドペプチターゼ / positive regulation of osteoblast differentiation / regulation of cytokine production / 骨化 / innate immune response in mucosa / recycling endosome / antibacterial humoral response / iron ion transport / エンドソーム / iron ion binding / signaling receptor binding / serine-type endopeptidase activity / negative regulation of apoptotic process / タンパク質分解 / extracellular space / 細胞膜 類似検索 - 分子機能
There are conflicts between seqres(LYS A 565, GLU A 608) and sequence database P24627 (ASN, LYS). ...There are conflicts between seqres(LYS A 565, GLU A 608) and sequence database P24627 (ASN, LYS). The authors believe that the SEQRES is correct. The conflicts are the true identity of these residues and are natural mutants.