登録情報 データベース : PDB / ID : 1r0n 構造の表示 ダウンロードとリンクタイトル Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex 要素Ecdsyone Response Element Ecdysone Response Element Ecdysone receptor Retinoic acid receptor RXR-alpha 詳細キーワード Transcription/DNA / Ecdysone receptor / nuclear receptor (核内受容体) / DNA binding domain (DNA結合ドメイン) / Ultraspiracle / RXR / Transcription-DNA COMPLEX機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
repressor ecdysone receptor complex / ecdysis, chitin-based cuticle / larval wandering behavior / regulation of Malpighian tubule diameter / regulation of neuron remodeling / compound eye photoreceptor fate commitment / larval development / ecdysone receptor holocomplex / activator ecdysone receptor complex / dorsal vessel heart proper cell fate commitment ... repressor ecdysone receptor complex / ecdysis, chitin-based cuticle / larval wandering behavior / regulation of Malpighian tubule diameter / regulation of neuron remodeling / compound eye photoreceptor fate commitment / larval development / ecdysone receptor holocomplex / activator ecdysone receptor complex / dorsal vessel heart proper cell fate commitment / ハッチング / regulation of hemocyte proliferation / Recycling of bile acids and salts / NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux / NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis / histoblast morphogenesis / chitin-based cuticle development / SUMOylation of intracellular receptors / chitin-based embryonic cuticle biosynthetic process / Nuclear Receptor transcription pathway / response to ecdysone / Malpighian tubule morphogenesis / larval central nervous system remodeling / VLDLR internalisation and degradation / head involution / ecdysone binding / germ-band shortening / pupariation / ecdysone receptor-mediated signaling pathway / cardioblast differentiation / regulation of development, heterochronic / positive regulation of neuron remodeling / mushroom body development / 変態 / border follicle cell migration / : / sperm individualization / imaginal disc-derived wing morphogenesis / positive regulation of circadian sleep/wake cycle, sleep / 多糸染色体 / positive regulation of transporter activity / retinoic acid-responsive element binding / NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis / NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose / NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake / positive regulation of thyroid hormone mediated signaling pathway / NR1H2 & NR1H3 regulate gene expression linked to lipogenesis / peripheral nervous system development / Carnitine metabolism / anatomical structure development / ion binding / cardiac muscle tissue development / Regulation of pyruvate dehydrogenase (PDH) complex / retinoic acid binding / regulation of cellular respiration / positive regulation of vitamin D receptor signaling pathway / nuclear vitamin D receptor binding / dendrite morphogenesis / Signaling by Retinoic Acid / DNA binding domain binding / nuclear steroid receptor activity / neuron remodeling / oogenesis / phagocytosis, engulfment / NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis / LBD domain binding / germ cell development / positive regulation of cholesterol efflux / Synthesis of bile acids and bile salts / long-term memory / epidermis development / retinoic acid receptor signaling pathway / Endogenous sterols / Synthesis of bile acids and bile salts via 27-hydroxycholesterol / positive regulation of bone mineralization / Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol / NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux / response to retinoic acid / core promoter sequence-specific DNA binding / Recycling of bile acids and salts / peroxisome proliferator activated receptor signaling pathway / RORA activates gene expression / Regulation of lipid metabolism by PPARalpha / steroid binding / hormone-mediated signaling pathway / cholesterol homeostasis / BMAL1:CLOCK,NPAS2 activates circadian gene expression / transcription corepressor binding / response to cocaine / Activation of gene expression by SREBF (SREBP) / regulation of autophagy / transcription coregulator binding / determination of adult lifespan / nuclear receptor binding / RNA polymerase II transcription regulatory region sequence-specific DNA binding / peptide binding / SUMOylation of intracellular receptors / Heme signaling / mRNA transcription by RNA polymerase II / Transcriptional activation of mitochondrial biogenesis 類似検索 - 分子機能 Ecdysteroid receptor / Ecdysone receptor, ligand-binding domain / Erythroid Transcription Factor GATA-1, subunit A / Nuclear/hormone receptor activator site AF-1 / Nuclear/hormone receptor activator site AF-1 / Erythroid Transcription Factor GATA-1; Chain A / Retinoid X receptor/HNF4 / 核内受容体 / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type ... Ecdysteroid receptor / Ecdysone receptor, ligand-binding domain / Erythroid Transcription Factor GATA-1, subunit A / Nuclear/hormone receptor activator site AF-1 / Nuclear/hormone receptor activator site AF-1 / Erythroid Transcription Factor GATA-1; Chain A / Retinoid X receptor/HNF4 / 核内受容体 / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Ligand-binding domain of nuclear hormone receptor / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Zinc finger, NHR/GATA-type / 2-Layer Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 デオキシリボ核酸 / DNA (> 10) / Retinoic acid receptor RXR-alpha / Ecdysone receptor 類似検索 - 構成要素生物種 Homo sapiens (ヒト)Drosophila melanogaster (キイロショウジョウバエ)手法 X線回折 / シンクロトロン / 多波長異常分散 / 解像度 : 2.6 Å 詳細データ登録者 Devarakonda, S. / Harp, J.M. / Kim, Y. / Ozyhar, A. / Rastinejad, F. 引用ジャーナル : Embo J. / 年 : 2003タイトル : Structure of the heterodimeric Ecdysone Receptor DNA-binding complex著者 : Devarakonda, S. / Harp, J.M. / Kim, Y. / Ozyhar, A. / Rastinejad, F. 履歴 登録 2003年9月22日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2003年10月21日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月29日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2024年2月14日 Group : Data collection / Database references / Derived calculationsカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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