登録情報 データベース : PDB / ID : 1nt0 構造の表示 ダウンロードとリンクタイトル Crystal structure of the CUB1-EGF-CUB2 region of MASP2 要素mannose-binding protein associated serine protease-2 詳細 キーワード HYDROLASE (加水分解酵素) / SUGAR BINDING PROTEIN / mannose-binding protein / MASP / CUB domain / EGF like domain.機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
mannan-binding lectin-associated serine protease-2 / Ficolins bind to repetitive carbohydrate structures on the target cell surface / complement component C4b binding / Lectin pathway of complement activation / Initial triggering of complement / complement activation, lectin pathway / 補体 / complement activation, classical pathway / calcium-dependent protein binding / peptidase activity ... mannan-binding lectin-associated serine protease-2 / Ficolins bind to repetitive carbohydrate structures on the target cell surface / complement component C4b binding / Lectin pathway of complement activation / Initial triggering of complement / complement activation, lectin pathway / 補体 / complement activation, classical pathway / calcium-dependent protein binding / peptidase activity / serine-type endopeptidase activity / calcium ion binding / タンパク質分解 / extracellular space 類似検索 - 分子機能 Spermadhesin, CUB domain / Peptidase S1A, complement C1r/C1S/mannan-binding / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily / Calcium-binding EGF domain / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) ... Spermadhesin, CUB domain / Peptidase S1A, complement C1r/C1S/mannan-binding / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily / Calcium-binding EGF domain / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) / Sushi/SCR/CCP domain / Sushi/SCR/CCP superfamily / Sushi/CCP/SCR domain profile. / ラミニン / ラミニン / EGF-like calcium-binding, conserved site / Calcium-binding EGF-like domain signature. / Aspartic acid and asparagine hydroxylation site. / EGF-like calcium-binding domain / Calcium-binding EGF-like domain / Epidermal growth factor-like domain. / EGF-like domain signature 2. / EGF様ドメイン / リボン / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / トリプシン / Jelly Rolls / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / サンドイッチ / Mainly Beta 類似検索 - ドメイン・相同性生物種 Rattus norvegicus (ドブネズミ)手法 X線回折 / シンクロトロン / 単一同系置換・異常分散 / 解像度 : 2.7 Å 詳細データ登録者 Feinberg, H. / Uitdehaag, J.C.M. / Davies, J.M. / Wallis, R. / Drickamer, K. / Weis, W.I. 引用ジャーナル : Embo J. / 年 : 2003タイトル : Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2著者 : Feinberg, H. / Uitdehaag, J.C.M. / Davies, J.M. / Wallis, R. / Drickamer, K. / Weis, W.I. 履歴 登録 2003年1月28日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2003年5月20日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月29日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Non-polymer description / Version format compliance改定 1.3 2017年10月11日 Group : Refinement description / カテゴリ : software改定 1.4 2020年7月29日 Group : Advisory / Data collection ... Advisory / Data collection / Database references / Derived calculations / Structure summary カテゴリ : chem_comp / database_PDB_caveat ... chem_comp / database_PDB_caveat / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item : _chem_comp.name / _chem_comp.type ... _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_ref_seq_dif.details 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation
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