+データを開く
-基本情報
登録情報 | データベース: PDB / ID: 1dgv | ||||||
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タイトル | HOMOLOGY-BASED MODEL OF APO CIB (CALCIUM-AND INTEGRIN-BINDING PROTEIN) | ||||||
要素 | APO CIB | ||||||
キーワード | BLOOD CLOTTING (凝固・線溶系) / HELICAL / EF-HAND (EFハンド) | ||||||
機能・相同性 | 機能・相同性情報 calcium-dependent protein kinase inhibitor activity / thrombopoietin-mediated signaling pathway / endomitotic cell cycle / positive regulation of male germ cell proliferation / filopodium tip / positive regulation of calcineurin-NFAT signaling cascade / negative regulation of microtubule depolymerization / protein serine/threonine kinase inhibitor activity / positive regulation of cell adhesion mediated by integrin / positive regulation of cell-matrix adhesion ...calcium-dependent protein kinase inhibitor activity / thrombopoietin-mediated signaling pathway / endomitotic cell cycle / positive regulation of male germ cell proliferation / filopodium tip / positive regulation of calcineurin-NFAT signaling cascade / negative regulation of microtubule depolymerization / protein serine/threonine kinase inhibitor activity / positive regulation of cell adhesion mediated by integrin / positive regulation of cell-matrix adhesion / platelet formation / positive regulation of cell migration involved in sprouting angiogenesis / positive regulation of catalytic activity / regulation of cell division / spermatid development / positive regulation of protein targeting to membrane / negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / negative regulation of megakaryocyte differentiation / cytoplasmic microtubule organization / protein-membrane adaptor activity / positive regulation of substrate adhesion-dependent cell spreading / extrinsic apoptotic signaling pathway / cellular response to nerve growth factor stimulus / negative regulation of protein phosphorylation / response to ischemia / cell periphery / positive regulation of protein localization to plasma membrane / 筋鞘 / positive regulation of protein serine/threonine kinase activity / cellular response to growth factor stimulus / small GTPase binding / ruffle membrane / double-strand break repair / negative regulation of neuron projection development / lamellipodium / cellular response to tumor necrosis factor / positive regulation of NF-kappaB transcription factor activity / regulation of cell population proliferation / 成長円錐 / perikaryon / positive regulation of cell growth / 血管新生 / vesicle / transmembrane transporter binding / positive regulation of ERK1 and ERK2 cascade / 細胞接着 / neuron projection / positive regulation of cell migration / positive regulation of protein phosphorylation / apical plasma membrane / 神経繊維 / 細胞分裂 / negative regulation of cell population proliferation / 中心体 / neuronal cell body / apoptotic process / DNA damage response / calcium ion binding / positive regulation of cell population proliferation / negative regulation of apoptotic process / perinuclear region of cytoplasm / ゴルジ体 / magnesium ion binding / 小胞体 / extracellular exosome / 核質 / 生体膜 / 細胞核 / 細胞膜 / 細胞質 類似検索 - 分子機能 | ||||||
生物種 | Homo sapiens (ヒト) | ||||||
手法 | 溶液NMR | ||||||
データ登録者 | Hwang, P.M. / Vogel, H.J. | ||||||
引用 | ジャーナル: J.Mol.Recog. / 年: 2000 タイトル: Structures of the platelet calcium- and integrin-binding protein and the alphaIIb-integrin cytoplasmic domain suggest a mechanism for calcium-regulated recognition; homology modelling and NMR studies. 著者: Hwang, P.M. / Vogel, H.J. | ||||||
履歴 |
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-構造の表示
構造ビューア | 分子: MolmilJmol/JSmol |
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-ダウンロードとリンク
-ダウンロード
PDBx/mmCIF形式 | 1dgv.cif.gz | 65.7 KB | 表示 | PDBx/mmCIF形式 |
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PDB形式 | pdb1dgv.ent.gz | 54.3 KB | 表示 | PDB形式 |
PDBx/mmJSON形式 | 1dgv.json.gz | ツリー表示 | PDBx/mmJSON形式 | |
その他 | その他のダウンロード |
-検証レポート
アーカイブディレクトリ | https://data.pdbj.org/pub/pdb/validation_reports/dg/1dgv ftp://data.pdbj.org/pub/pdb/validation_reports/dg/1dgv | HTTPS FTP |
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-関連構造データ
-リンク
-集合体
登録構造単位 |
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1 |
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NMR アンサンブル |
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-要素
#1: タンパク質 | 分子量: 20980.490 Da / 分子数: 1 / 由来タイプ: 天然 / 由来: (天然) Homo sapiens (ヒト) / 参照: UniProt: Q99828 |
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-実験情報
-実験
実験 | 手法: 溶液NMR |
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-試料調製
結晶化 | *PLUS 手法: その他 / 詳細: NMR |
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-解析
NMRアンサンブル | 登録したコンフォーマーの数: 1 |
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