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- SASDGW4: Model of the LZ1 domain of C-Jun-amino-terminal kinase-interactin... -

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Basic information

Entry
Database: SASBDB / ID: SASDGW4
SampleModel of the LZ1 domain of C-Jun-amino-terminal kinase-interacting protein 3 (JIP3)
  • C-Jun-amino-terminal kinase-interacting protein 3 (protein), JIP3, Homo sapiens
Function / homology
Function and homology information


anterograde axonal protein transport / MAP-kinase scaffold activity / JUN kinase binding / regulation of JNK cascade / axon regeneration / axon development / kinesin binding / vesicle-mediated transport / axon cytoplasm / positive regulation of JNK cascade ...anterograde axonal protein transport / MAP-kinase scaffold activity / JUN kinase binding / regulation of JNK cascade / axon regeneration / axon development / kinesin binding / vesicle-mediated transport / axon cytoplasm / positive regulation of JNK cascade / signaling receptor complex adaptor activity / cell body / growth cone / cytoplasmic vesicle / protein stabilization / Golgi membrane / axon / dendrite / negative regulation of apoptotic process / perinuclear region of cytoplasm / cytoplasm
Similarity search - Function
JNK-interacting protein, leucine zipper II / JNK-interacting protein 3/4 / JNK-interacting protein leucine zipper II / WD40 repeated domain / RH1 domain / RH2 domain / RILP homology 1 domain / RH1 domain profile. / RH2 domain profile. / WD40-repeat-containing domain superfamily / WD40/YVTN repeat-like-containing domain superfamily
Similarity search - Domain/homology
C-Jun-amino-terminal kinase-interacting protein 3
Similarity search - Component
Biological speciesHomo sapiens (human)
Contact author
  • Paola Llinas (I2BC-CNRS, Paris, France)

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

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Models

Model #2988
Type: atomic / Chi-square value: 1.543
Search similar-shape structures of this assembly by Omokage search (details)

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Sample

SampleName: Model of the LZ1 domain of C-Jun-amino-terminal kinase-interacting protein 3 (JIP3)
Specimen concentration: 6 mg/ml
BufferName: 20 mM HEPES, 300 mM NaCl, 0.5 mM TCEP / pH: 7.1
Entity #1617Name: JIP3 / Type: protein
Description: C-Jun-amino-terminal kinase-interacting protein 3
Formula weight: 20.016 / Num. of mol.: 2 / Source: Homo sapiens / References: UniProt: Q9UPT6
Sequence:
GSVMSERVSG LAGSIYREFE RLIHCYDEEV VKELMPLVVN VLENLDSVLS ENQEHEVELE LLREDNEQLL TQYEREKALR RQAEEKFIEF EDALEQEKKE LQIQVEHYEF QTRQLELKAK NYADQISRLE ERESEMKKEY NALHQRHTEM IQTYVEHIER SKMQQV

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Experimental information

BeamInstrument name: SOLEIL SWING / City: Saint-Aubin / 国: France / Type of source: X-ray synchrotron / Wavelength: 0.1033 Å / Dist. spec. to detc.: 1.5 mm
DetectorName: Eiger 4M / Pixsize x: 75 mm
Scan
Title: Model of the LZ1 domain of C-Jun-amino-terminal kinase-interacting protein 3 (JIP3)
Measurement date: Sep 22, 2018 / Storage temperature: 10 °C / Cell temperature: 15 °C / Exposure time: 0.99 sec. / Unit: 1/A /
MinMax
Q0.0049 0.8167
Distance distribution function P(R)
Sofotware P(R): GNOM 5.0 / Number of points: 1194 /
MinMax
Q0.00851413 0.730068
P(R) point1 1194
R0 198
Result
Type of curve: sec /
ExperimentalPorod
MW33.4 kDa-
Volume-84 nm3

P(R)GuinierGuinier error
Forward scattering, I00.03848 0.038 0.00013
Radius of gyration, Rg5.39 nm5.01 nm0.32

MinMax
D-19.8
Guinier point11 32

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