Entry Database : PDB / ID : 8tlz Structure visualization Downloads & linksTitle Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys ComponentsMHC class I polypeptide-related sequence A Details Keywords IMMUNE SYSTEM / modified MICA / ligand NKG2DFunction / homology Function and homology informationFunction Domain/homology Component
immune response to tumor cell / natural killer cell lectin-like receptor binding / negative regulation of natural killer cell activation / gamma-delta T cell activation / negative regulation of natural killer cell mediated cytotoxicity / natural killer cell mediated cytotoxicity / T cell mediated cytotoxicity / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / response to heat / defense response to virus ... immune response to tumor cell / natural killer cell lectin-like receptor binding / negative regulation of natural killer cell activation / gamma-delta T cell activation / negative regulation of natural killer cell mediated cytotoxicity / natural killer cell mediated cytotoxicity / T cell mediated cytotoxicity / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / response to heat / defense response to virus / killing of cells of another organism / defense response to bacterium / immune response / receptor ligand activity / external side of plasma membrane / DNA damage response / cell surface / extracellular space / plasma membrane / cytoplasm Similarity search - Function Class I Histocompatibility antigen, domains alpha 1 and 2 / : / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / MHC classes I/II-like antigen recognition protein / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain ... Class I Histocompatibility antigen, domains alpha 1 and 2 / : / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / MHC classes I/II-like antigen recognition protein / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.75 Å DetailsAuthors Rupert, P.B. / Strong, R. Funding support 1items Details Hide detailsOrganization Grant number Country Not funded
CitationJournal : Heliyon / Year : 2024Title : Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.Authors : Rupert, P.B. / Buerger, M. / Girard, E.J. / Frutoso, M. / Parrilla, D. / Ng, K. / Gooley, T. / Groh, V. / Strong, R.K. History Deposition Jul 27, 2023 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Apr 17, 2024 Provider : repository / Type : Initial releaseRevision 1.1 Nov 13, 2024 Group : Structure summary / Category : pdbx_entry_details / pdbx_modification_feature / Item : _pdbx_entry_details.has_protein_modification
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