- PDB-8hyc: Crystal structure of B1 NDM-1 MBL in complex with 2-amino-5-(2-(t... -
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Entry
Database: PDB / ID: 8hyc
Title
Crystal structure of B1 NDM-1 MBL in complex with 2-amino-5-(2-(thiophen-2-yl)ethyl)thiazole-4-carboxylic acid
Components
Metallo-beta-lactamase type 2
Keywords
HYDROLASE / Beta-lactamase class B NDM-1
Function / homology
Function and homology information
antibiotic catabolic process / beta-lactamase activity / beta-lactamase / periplasmic space / response to antibiotic / zinc ion binding Similarity search - Function
Metallo-beta-lactamasetype2 / B2 metallo-beta-lactamase / Beta-lactamase type II / Metallo-beta-lactamase NDM-1 / Metallo-beta- ...B2 metallo-beta-lactamase / Beta-lactamase type II / Metallo-beta-lactamase NDM-1 / Metallo-beta-lactamase type II / New Delhi metallo-beta-lactamase-1 / NDM-1
Mass: 25574.768 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Details: Depositor stated that they had conducted structure refinement for several times and the Rwork value was still about 0.2493, which may due to the trivial density in asymmetric units. Source: (gene. exp.) Klebsiella pneumoniae (bacteria) / Gene: blaNDM-1 / Production host: Escherichia coli BL21(DE3) (bacteria) / References: UniProt: C7C422, beta-lactamase
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