Entry | Database: PDB / ID: 8hy5 |
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Title | Structure of D-amino acid oxidase mutant R38H |
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Components | D-amino-acid oxidase |
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Keywords | OXIDOREDUCTASE / ALS / amino acid / d-serine / neurodegeneration / schizophrenia |
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Function / homology | Function and homology information
D-alanine catabolic process / D-amino-acid oxidase / D-amino-acid oxidase activity / D-serine metabolic process / proline catabolic process / D-serine catabolic process / D-amino acid catabolic process / Glyoxylate metabolism and glycine degradation / dopamine biosynthetic process / presynaptic active zone ...D-alanine catabolic process / D-amino-acid oxidase / D-amino-acid oxidase activity / D-serine metabolic process / proline catabolic process / D-serine catabolic process / D-amino acid catabolic process / Glyoxylate metabolism and glycine degradation / dopamine biosynthetic process / presynaptic active zone / neutrophil-mediated killing of gram-negative bacterium / peroxisomal matrix / digestion / FAD binding / Peroxisomal protein import / identical protein binding / cytoplasm / cytosolSimilarity search - Function D-amino acid oxidase, conserved site / D-amino-acid oxidase / D-amino acid oxidases signature. / FAD dependent oxidoreductase / FAD dependent oxidoreductaseSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.1 Å |
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Authors | Khan, S. / Upadhyay, S. / Dave, U. / Kumar, A. / Gomes, J. |
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Funding support | India, 1items Organization | Grant number | Country |
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Other government | | India |
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Citation | Journal: Int.J.Biol.Macromol. / Year: 2023 Title: Structural and mechanistic insights into ALS patient derived mutations in D-amino acid oxidase. Authors: Khan, S. / Upadhyay, S. / Dave, U. / Kumar, A. / Gomes, J. |
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History | Deposition | Jan 5, 2023 | Deposition site: PDBJ / Processing site: PDBJ |
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Revision 1.0 | Jan 25, 2023 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 10, 2024 | Group: Data collection / Database references / Category: chem_comp_atom / chem_comp_bond / citation Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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