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Structure paper

TitleStructural and mechanistic insights into ALS patient derived mutations in D-amino acid oxidase.
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 256, Page 128403-128403, Year 2023
Publish dateJan 5, 2023 (structure data deposition date)
AuthorsKhan, S. / Upadhyay, S. / Dave, U. / Kumar, A. / Gomes, J.
External linksInt. J. Biol. Macromol. / PubMed:38035964
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-8hy5:
Structure of D-amino acid oxidase mutant R38H
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-BEZ:
BENZOIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / ALS / amino acid / d-serine / neurodegeneration / schizophrenia

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