登録情報 | データベース: PDB / ID: 8g7d |
---|
タイトル | Cryo-EM structure of full length Neuroligin-2 from Mouse |
---|
要素 | Neuroligin-1,Neuroligin-2 |
---|
キーワード | MEMBRANE PROTEIN / Neuroligin-2 |
---|
機能・相同性 | 機能・相同性情報
neurexin clustering involved in presynaptic membrane assembly / cell-cell adhesion involved in synapse maturation / cytoskeletal matrix organization at active zone / positive regulation of synaptic vesicle exocytosis / positive regulation of circadian sleep/wake cycle, wakefulness / negative regulation of dendritic spine morphogenesis / Neurexins and neuroligins / protein complex involved in cell-cell adhesion / positive regulation of neuromuscular synaptic transmission / neuron to neuron synapse ...neurexin clustering involved in presynaptic membrane assembly / cell-cell adhesion involved in synapse maturation / cytoskeletal matrix organization at active zone / positive regulation of synaptic vesicle exocytosis / positive regulation of circadian sleep/wake cycle, wakefulness / negative regulation of dendritic spine morphogenesis / Neurexins and neuroligins / protein complex involved in cell-cell adhesion / positive regulation of neuromuscular synaptic transmission / neuron to neuron synapse / jump response / neurotransmitter-gated ion channel clustering / positive regulation of t-SNARE clustering / postsynaptic specialization assembly / excitatory synapse assembly / gephyrin clustering involved in postsynaptic density assembly / terminal button organization / postsynaptic density protein 95 clustering / positive regulation of synaptic vesicle clustering / postsynaptic membrane assembly / synapse maturation / maintenance of synapse structure / presynaptic membrane assembly / synaptic vesicle targeting / synaptic vesicle clustering / thigmotaxis / ribbon synapse / synaptic membrane adhesion / receptor localization to synapse / filopodium tip / neuron cell-cell adhesion / insulin metabolic process / regulation of respiratory gaseous exchange by nervous system process / neurexin family protein binding / NMDA glutamate receptor clustering / inhibitory synapse / presynapse assembly / positive regulation of synaptic vesicle endocytosis / calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules / regulation of postsynaptic density assembly / AMPA glutamate receptor clustering / protein localization to synapse / dopaminergic synapse / positive regulation of inhibitory postsynaptic potential / glycinergic synapse / AMPA selective glutamate receptor signaling pathway / inhibitory synapse assembly / positive regulation of synapse assembly / protein localization to cell surface / NMDA selective glutamate receptor signaling pathway / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / positive regulation of filopodium assembly / regulation of neuron differentiation / postsynaptic specialization membrane / positive regulation of protein localization to synapse / synaptic transmission, GABAergic / positive regulation of dendritic spine development / social behavior / locomotory exploration behavior / neuromuscular process controlling balance / excitatory synapse / positive regulation of excitatory postsynaptic potential / regulation of presynapse assembly / synaptic cleft / synapse assembly / cell adhesion molecule binding / sensory perception of pain / positive regulation of synaptic transmission, glutamatergic / dendritic shaft / neuron projection morphogenesis / positive regulation of synaptic transmission, GABAergic / GABA-ergic synapse / establishment of protein localization / modulation of chemical synaptic transmission / synapse organization / neuromuscular junction / positive regulation of insulin secretion / positive regulation of neuron projection development / rhythmic process / nervous system development / presynapse / presynaptic membrane / dendritic spine / postsynaptic membrane / receptor complex / postsynaptic density / external side of plasma membrane / axon / positive regulation of cell population proliferation / synapse / dendrite / glutamatergic synapse / cell surface / Golgi apparatus / identical protein binding / plasma membrane類似検索 - 分子機能 Neuroligin / : / Carboxylesterase type B, conserved site / Carboxylesterases type-B signature 2. / Carboxylesterase, type B / Carboxylesterase family / Alpha/Beta hydrolase fold類似検索 - ドメイン・相同性 |
---|
生物種 |  Mus musculus (ハツカネズミ) |
---|
手法 | 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.28 Å |
---|
データ登録者 | Boyd, R. / Wang, W. |
---|
資金援助 | 米国, 2件 組織 | 認可番号 | 国 |
---|
National Institutes of Health/National Cancer Institute (NIH/NCI) | 1R25Gm146860 | 米国 | McKnight Foundation | 2022 Scholar Award | 米国 |
|
---|
引用 | ジャーナル: To Be Published タイトル: Cryo-EM structure of full length mouse Neuroligin-2 at 3.28 Angstroms resolution 著者: Boyd, R. / Wang, W. |
---|
履歴 | 登録 | 2023年2月16日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2025年5月14日 | Provider: repository / タイプ: Initial release |
---|
改定 1.0 | 2025年5月14日 | Data content type: EM metadata / Data content type: EM metadata / Provider: repository / タイプ: Initial release |
---|
改定 1.0 | 2025年5月14日 | Data content type: Half map / Part number: 1 / Data content type: Half map / Provider: repository / タイプ: Initial release |
---|
改定 1.0 | 2025年5月14日 | Data content type: Half map / Part number: 2 / Data content type: Half map / Provider: repository / タイプ: Initial release |
---|
改定 1.0 | 2025年5月14日 | Data content type: Image / Data content type: Image / Provider: repository / タイプ: Initial release |
---|
改定 1.0 | 2025年5月14日 | Data content type: Primary map / Data content type: Primary map / Provider: repository / タイプ: Initial release |
---|
|
---|