登録情報 データベース : PDB / ID : 8fd0 構造の表示 ダウンロードとリンクタイトル Crystal structure of bovine rod opsin in complex with a nanobody 要素 詳細 キーワード MEMBRANE PROTEIN / TRANSMEMBRANE PROTEIN / GPCR / NANOBODY機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Opsins / VxPx cargo-targeting to cilium / opsin binding / rod bipolar cell differentiation / rod photoreceptor outer segment / sperm head plasma membrane / absorption of visible light / The canonical retinoid cycle in rods (twilight vision) / : / photoreceptor inner segment membrane ... Opsins / VxPx cargo-targeting to cilium / opsin binding / rod bipolar cell differentiation / rod photoreceptor outer segment / sperm head plasma membrane / absorption of visible light / The canonical retinoid cycle in rods (twilight vision) / : / photoreceptor inner segment membrane / podosome assembly / G protein-coupled opsin signaling pathway / 11-cis retinal binding / G protein-coupled photoreceptor activity / cellular response to light stimulus / G protein-coupled receptor complex / Inactivation, recovery and regulation of the phototransduction cascade / thermotaxis / Activation of the phototransduction cascade / phototransduction, visible light / outer membrane / detection of temperature stimulus involved in thermoception / photoreceptor cell maintenance / arrestin family protein binding / photoreceptor outer segment membrane / G alpha (i) signalling events / phototransduction / photoreceptor outer segment / G-protein alpha-subunit binding / response to light stimulus / sperm midpiece / visual perception / guanyl-nucleotide exchange factor activity / photoreceptor disc membrane / microtubule cytoskeleton organization / cell-cell junction / gene expression / G protein-coupled receptor signaling pathway / Golgi membrane / zinc ion binding / identical protein binding / membrane / plasma membrane 類似検索 - 分子機能 Rhodopsin, N-terminal / Amino terminal of the G-protein receptor rhodopsin / Rhodopsin / Opsin / Visual pigments (opsins) retinal binding site / Visual pigments (opsins) retinal binding site. / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM ... Rhodopsin, N-terminal / Amino terminal of the G-protein receptor rhodopsin / Rhodopsin / Opsin / Visual pigments (opsins) retinal binding site / Visual pigments (opsins) retinal binding site. / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) 類似検索 - ドメイン・相同性生物種 Lama glama (ラマ)Bos taurus (ウシ)手法 X線回折 / シンクロトロン / フーリエ合成 / 解像度 : 3.71 Å 詳細データ登録者 Salom, D. / Palczewski, K. / Kiser, P.D. 資金援助 米国, 3件 詳細 詳細を隠す組織 認可番号 国 National Institutes of Health/National Eye Institute (NIH/NEI) EY009339 米国 Department of Veterans Affairs (VA, United States) I01 BX004939 米国 National Science Foundation (NSF, United States) CHE-2107713 米国
引用ジャーナル : Nat Commun / 年 : 2023タイトル : Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.著者 : Wu, A. / Salom, D. / Hong, J.D. / Tworak, A. / Watanabe, K. / Pardon, E. / Steyaert, J. / Kandori, H. / Katayama, K. / Kiser, P.D. / Palczewski, K. 履歴 登録 2022年12月1日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2023年8月30日 Provider : repository / タイプ : Initial release改定 1.1 2023年9月20日 Group : Database references / カテゴリ : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year
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