+Open data
-Basic information
Entry | Database: PDB / ID: 8e0p | |||||||||
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Title | Crystal structure of mouse APCDD1 in fusion with engineered MBP | |||||||||
Components | Maltodextrin-binding protein, Protein APCDD1 complex | |||||||||
Keywords | SIGNALING PROTEIN / cell signaling protein / beta barrel / lipid binding protein | |||||||||
Function / homology | Function and homology information regulation of odontogenesis of dentin-containing tooth / astrocyte cell migration / Wnt-protein binding / negative regulation of Wnt signaling pathway / maltose binding / maltose transport / maltodextrin transmembrane transport / carbohydrate transmembrane transporter activity / hair follicle development / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing ...regulation of odontogenesis of dentin-containing tooth / astrocyte cell migration / Wnt-protein binding / negative regulation of Wnt signaling pathway / maltose binding / maltose transport / maltodextrin transmembrane transport / carbohydrate transmembrane transporter activity / hair follicle development / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing / Wnt signaling pathway / outer membrane-bounded periplasmic space / identical protein binding / plasma membrane Similarity search - Function | |||||||||
Biological species | Escherichia coli (E. coli) Mus musculus (house mouse) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.33 Å | |||||||||
Authors | Hsieh, F.L. / Chang, T.H. / Gabelli, S.B. / Nathans, J. | |||||||||
Funding support | United States, 2items
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Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2023 Title: Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein. Authors: Hsieh, F.L. / Chang, T.H. / Gabelli, S.B. / Nathans, J. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 8e0p.cif.gz | 1.2 MB | Display | PDBx/mmCIF format |
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PDB format | pdb8e0p.ent.gz | Display | PDB format | |
PDBx/mmJSON format | 8e0p.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 8e0p_validation.pdf.gz | 3.1 MB | Display | wwPDB validaton report |
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Full document | 8e0p_full_validation.pdf.gz | 3.2 MB | Display | |
Data in XML | 8e0p_validation.xml.gz | 125.6 KB | Display | |
Data in CIF | 8e0p_validation.cif.gz | 168.9 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/e0/8e0p ftp://data.pdbj.org/pub/pdb/validation_reports/e0/8e0p | HTTPS FTP |
-Related structure data
Related structure data | 8e0rC 8e0wC 3setS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
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Noncrystallographic symmetry (NCS) | NCS domain:
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