登録情報 | データベース: PDB / ID: 8bn5 |
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タイトル | Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA |
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要素 | Glutamate receptor ionotropic, delta-1 |
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キーワード | MEMBRANE PROTEIN / ion channel / ligand binding domain / glutamate receptor / GABA |
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機能・相同性 | 機能・相同性情報
glutamate receptor signaling pathway / glutamate receptor activity / regulation of postsynapse organization / social behavior / GABA-ergic synapse / synaptic transmission, glutamatergic / transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential / postsynaptic density membrane / modulation of chemical synaptic transmission / glutamatergic synapse ...glutamate receptor signaling pathway / glutamate receptor activity / regulation of postsynapse organization / social behavior / GABA-ergic synapse / synaptic transmission, glutamatergic / transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential / postsynaptic density membrane / modulation of chemical synaptic transmission / glutamatergic synapse / extracellular exosome / identical protein binding / plasma membrane類似検索 - 分子機能 Ionotropic glutamate receptor, metazoa / Ligated ion channel L-glutamate- and glycine-binding site / : / Ligand-gated ion channel / Ionotropic glutamate receptor, L-glutamate and glycine-binding domain / Ligated ion channel L-glutamate- and glycine-binding site / Ionotropic glutamate receptor / Eukaryotic homologues of bacterial periplasmic substrate binding proteins. / Receptor, ligand binding region / Receptor family ligand binding region / Periplasmic binding protein-like I類似検索 - ドメイン・相同性 GAMMA-AMINO-BUTANOIC ACID / Glutamate receptor ionotropic, delta-1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.9 Å |
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データ登録者 | Heroven, C. / Malinauskas, T. / Aricescu, A.R. |
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資金援助 | 英国, 2件 組織 | 認可番号 | 国 |
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Medical Research Council (MRC, United Kingdom) | MR/L009609/1 | 英国 | Medical Research Council (MRC, United Kingdom) | MC_UP_1201/15 | 英国 |
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引用 | ジャーナル: Science / 年: 2023 タイトル: GluD1 binds GABA and controls inhibitory plasticity. 著者: Piot, L. / Heroven, C. / Bossi, S. / Zamith, J. / Malinauskas, T. / Johnson, C. / Wennagel, D. / Stroebel, D. / Charrier, C. / Aricescu, A.R. / Mony, L. / Paoletti, P. |
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履歴 | 登録 | 2022年11月12日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2023年11月22日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年12月13日 | Group: Database references / カテゴリ: citation Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.title / _citation.year |
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改定 1.2 | 2023年12月20日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.page_first / _citation.page_last ..._citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title |
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改定 1.3 | 2024年1月3日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation_author.identifier_ORCID |
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