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- PDB-7x4i: Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV... -
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Basic information
Entry | Database: PDB / ID: 7x4i | |||||||||
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Title | Crystal structure of nanobody aSA3 in complex with dimer SARS-CoV-1 RBD | |||||||||
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![]() | ANTIVIRAL PROTEIN / Nanobody / SARS-CoV-1 / RBD | |||||||||
Function / homology | ![]() : / endocytosis involved in viral entry into host cell / membrane => GO:0016020 / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated virion attachment to host cell / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / host cell plasma membrane / virion membrane Similarity search - Function | |||||||||
Biological species | ![]() ![]() ![]() | |||||||||
Method | ![]() ![]() ![]() | |||||||||
![]() | Ma, H. / Zeng, W.H. / Jin, T.C. | |||||||||
Funding support | ![]()
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![]() | ![]() Title: A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration. Authors: Ma, H. / Zhang, X. / Zeng, W. / Zhou, J. / Chi, X. / Chen, S. / Zheng, P. / Wang, M. / Wu, Y. / Zhao, D. / Gong, F. / Lin, H. / Sun, H. / Yu, C. / Shi, Z. / Hu, X. / Zhang, H. / Jin, T. / Chiu, S. | |||||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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PDBx/mmCIF format | ![]() | 486.8 KB | Display | ![]() |
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PDB format | ![]() | 405.1 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 493.1 KB | Display | ![]() |
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Full document | ![]() | 515.3 KB | Display | |
Data in XML | ![]() | 43.3 KB | Display | |
Data in CIF | ![]() | 58.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 70lzS ![]() 7lm9S S: Starting model for refinement |
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Similar structure data | Similarity search - Function & homology ![]() |
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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