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-Structure paper
Title | A bispecific nanobody dimer broadly neutralizes SARS-CoV-1 & 2 variants of concern and offers substantial protection against Omicron via low-dose intranasal administration. |
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Journal, issue, pages | Cell Discov, Vol. 8, Page 132-132, Year 2022 |
Publish date | Mar 2, 2022 (structure data deposition date) |
Authors | Ma, H. / Zhang, X. / Zeng, W. / Zhou, J. / Chi, X. / Chen, S. / Zheng, P. / Wang, M. / Wu, Y. / Zhao, D. ...Ma, H. / Zhang, X. / Zeng, W. / Zhou, J. / Chi, X. / Chen, S. / Zheng, P. / Wang, M. / Wu, Y. / Zhao, D. / Gong, F. / Lin, H. / Sun, H. / Yu, C. / Shi, Z. / Hu, X. / Zhang, H. / Jin, T. / Chiu, S. |
External links | Cell Discov / PubMed:36494344 |
Methods | X-ray diffraction |
Resolution | 3.38 Å |
Structure data | PDB-7x4i: |
Source |
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Keywords | ANTIVIRAL PROTEIN / Nanobody / SARS-CoV-1 / RBD |