登録情報 データベース : PDB / ID : 7w6t 構造の表示 ダウンロードとリンクタイトル CryoEM structure of human KChIP1-Kv4.3-DPP6 complex 要素Dipeptidyl aminopeptidase-like protein 6 Isoform 2 of Potassium voltage-gated channel subfamily D member 3 Kv channel-interacting protein 1 詳細キーワード MEMBRANE PROTEIN / Kv channel-interacting protein 1 Potassium voltage-gated channel Dipeptidyl aminopeptidase-like protein 6機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
ventricular cardiac muscle cell membrane repolarization / A-type (transient outward) potassium channel activity / Phase 1 - inactivation of fast Na+ channels / membrane repolarization during ventricular cardiac muscle cell action potential / membrane repolarization during cardiac muscle cell action potential / potassium ion export across plasma membrane / membrane repolarization / Voltage gated Potassium channels / regulation of potassium ion transmembrane transport / postsynaptic specialization membrane ... ventricular cardiac muscle cell membrane repolarization / A-type (transient outward) potassium channel activity / Phase 1 - inactivation of fast Na+ channels / membrane repolarization during ventricular cardiac muscle cell action potential / membrane repolarization during cardiac muscle cell action potential / potassium ion export across plasma membrane / membrane repolarization / Voltage gated Potassium channels / regulation of potassium ion transmembrane transport / postsynaptic specialization membrane / voltage-gated potassium channel activity / potassium channel activity / regulation of heart rate by cardiac conduction / GABA-ergic synapse / potassium channel regulator activity / voltage-gated potassium channel complex / serine-type peptidase activity / potassium ion transport / protein homooligomerization / cytoplasmic side of plasma membrane / sarcolemma / postsynaptic membrane / transmembrane transporter binding / dendritic spine / neuronal cell body / calcium ion binding / dendrite / proteolysis / metal ion binding / plasma membrane / cytoplasm 類似検索 - 分子機能 Potassium channel, voltage dependent, Kv4.3 / Potassium channel, voltage dependent, Kv4 / Shal-type voltage-gated potassium channels, N-terminal / Potassium channel, voltage dependent, Kv4, C-terminal / Shal-type voltage-gated potassium channels, N-terminal / Domain of unknown function (DUF3399) / Recoverin family / Potassium channel, voltage dependent, Kv / Potassium channel tetramerisation-type BTB domain / BTB/POZ domain ... Potassium channel, voltage dependent, Kv4.3 / Potassium channel, voltage dependent, Kv4 / Shal-type voltage-gated potassium channels, N-terminal / Potassium channel, voltage dependent, Kv4, C-terminal / Shal-type voltage-gated potassium channels, N-terminal / Domain of unknown function (DUF3399) / Recoverin family / Potassium channel, voltage dependent, Kv / Potassium channel tetramerisation-type BTB domain / BTB/POZ domain / Dipeptidylpeptidase IV, N-terminal domain / Dipeptidyl peptidase IV (DPP IV) N-terminal region / EF-hand domain pair / Peptidase S9, prolyl oligopeptidase, catalytic domain / Prolyl oligopeptidase family / Broad-Complex, Tramtrack and Bric a brac / BTB/POZ domain / Voltage-dependent channel domain superfamily / SKP1/BTB/POZ domain superfamily / EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / Ion transport domain / Ion transport protein / EF-hand domain pair / Alpha/Beta hydrolase fold 類似検索 - ドメイン・相同性 Dipeptidyl aminopeptidase-like protein 6 / Kv channel-interacting protein 1 / Potassium voltage-gated channel subfamily D member 3 類似検索 - 構成要素生物種 Homo sapiens (ヒト)Mus musculus (ハツカネズミ)手法 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度 : 3.85 Å 詳細データ登録者 Ma, D.M. / Guo, J.T. 資金援助 中国, 4件 詳細 詳細を隠す組織 認可番号 国 Ministry of Science and Technology (MoST, China) 2021FZZX001-28 中国 Ministry of Science and Technology (MoST, China) LD21H020001 中国 National Natural Science Foundation of China (NSFC) LR19C050002 中国 National Natural Science Foundation of China (NSFC) LY19H020007 中国
引用ジャーナル : Cell Res / 年 : 2022タイトル : Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.著者 : Demin Ma / Cheng Zhao / Xiaochen Wang / Xiaoxiao Li / Yi Zha / Yan Zhang / Guosheng Fu / Ping Liang / Jiangtao Guo / Dongwu Lai / 履歴 登録 2021年12月2日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2022年11月2日 Provider : repository / タイプ : Initial release