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Yorodumi- PDB-7s87: Crystal Structure of Dihydroorotate dehydrogenase from Plasmodium... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7s87 | ||||||
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Title | Crystal Structure of Dihydroorotate dehydrogenase from Plasmodium falciparum in complex with Orotate, FMN, and inhibitor NCGC00600348-01 | ||||||
Components | Dihydroorotate dehydrogenase (quinone), mitochondrial | ||||||
Keywords | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / inhibitor / DHODH / TIM Barrel / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / SSGCID / OXIDOREDUCTASE / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex | ||||||
Function / homology | Function and homology information Pyrimidine biosynthesis / pyrimidine ribonucleotide biosynthetic process / dihydroorotate dehydrogenase (quinone) activity / dihydroorotate dehydrogenase (quinone) / dihydroorotate dehydrogenase activity / 'de novo' UMP biosynthetic process / 'de novo' pyrimidine nucleobase biosynthetic process / mitochondrial inner membrane Similarity search - Function | ||||||
Biological species | Plasmodium falciparum (malaria parasite P. falciparum) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.75 Å | ||||||
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | ||||||
Funding support | United States, 1items
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Citation | Journal: To Be Published Title: Crystal Structure of Dihydroorotate dehydrogenase from Plasmodium falciparum in complex with Orotate, FMN, and inhibitor NCGC00600348-01 Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) / Shek, R. / Abendroth, J. / Lorimer, D. / Edwards, T.E. / Eastman, R. / Van Voorhis, W. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7s87.cif.gz | 376.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7s87.ent.gz | 254.4 KB | Display | PDB format |
PDBx/mmJSON format | 7s87.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7s87_validation.pdf.gz | 2.6 MB | Display | wwPDB validaton report |
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Full document | 7s87_full_validation.pdf.gz | 2.6 MB | Display | |
Data in XML | 7s87_validation.xml.gz | 30.6 KB | Display | |
Data in CIF | 7s87_validation.cif.gz | 40.9 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/s8/7s87 ftp://data.pdbj.org/pub/pdb/validation_reports/s8/7s87 | HTTPS FTP |
-Related structure data
Related structure data | 6vtyS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Components on special symmetry positions |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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