+データを開く
-基本情報
登録情報 | データベース: PDB / ID: 7qs8 | ||||||
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タイトル | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | ||||||
要素 |
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キーワード | VIRAL PROTEIN / Human T lymphotrophic virus-1 / HTLV-1 / cell polarity / isothermal titration calorimetry / Tax1 / PDZ / scribble | ||||||
機能・相同性 | 機能・相同性情報 symbiont-mediated perturbation of host exit from mitosis / symbiont-mediated activation of host NF-kappaB cascade / symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint / neurotransmitter receptor transport postsynaptic membrane to endosome / establishment of T cell polarity / extrinsic component of postsynaptic density membrane / apoptotic process involved in morphogenesis / establishment of apical/basal cell polarity / cochlear nucleus development / Scrib-APC-beta-catenin complex ...symbiont-mediated perturbation of host exit from mitosis / symbiont-mediated activation of host NF-kappaB cascade / symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint / neurotransmitter receptor transport postsynaptic membrane to endosome / establishment of T cell polarity / extrinsic component of postsynaptic density membrane / apoptotic process involved in morphogenesis / establishment of apical/basal cell polarity / cochlear nucleus development / Scrib-APC-beta-catenin complex / astrocyte cell migration / synaptic vesicle targeting / polarized epithelial cell differentiation / epithelial structure maintenance / myelin sheath abaxonal region / neurotransmitter receptor transport, endosome to postsynaptic membrane / protein localization to adherens junction / cell-cell contact zone / mammary gland duct morphogenesis / post-anal tail morphogenesis / establishment or maintenance of epithelial cell apical/basal polarity / activation of GTPase activity / auditory receptor cell stereocilium organization / regulation of postsynaptic neurotransmitter receptor internalization / RND2 GTPase cycle / RND3 GTPase cycle / receptor clustering / positive chemotaxis / positive regulation of receptor recycling / symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint / RHOJ GTPase cycle / RHOQ GTPase cycle / negative regulation of activated T cell proliferation / CDC42 GTPase cycle / negative regulation of mitotic cell cycle / immunological synapse / synaptic vesicle endocytosis / signaling adaptor activity / regulation of mRNA stability / neural tube closure / Asymmetric localization of PCP proteins / adherens junction / wound healing / SH3 domain binding / cell-cell adhesion / positive regulation of type II interferon production / cell-cell junction / cell migration / cell junction / lamellipodium / presynapse / cellular response to lipopolysaccharide / basolateral plasma membrane / host cell cytoplasm / cell population proliferation / postsynaptic density / cadherin binding / positive regulation of apoptotic process / negative regulation of gene expression / glutamatergic synapse / host cell nucleus / protein kinase binding / positive regulation of DNA-templated transcription / DNA binding / extracellular exosome / nucleoplasm / metal ion binding / plasma membrane / cytoplasm 類似検索 - 分子機能 | ||||||
生物種 | Homo sapiens (ヒト) Human T-cell leukemia virus type I (ウイルス) | ||||||
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.85 Å | ||||||
データ登録者 | Javorsky, A. / Soares da Costa, T.P. / Mackie, E.R. / Humbert, P.O. / Kvansakul, M. | ||||||
資金援助 | 1件
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引用 | ジャーナル: Febs J. / 年: 2023 タイトル: Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. 著者: Javorsky, A. / Maddumage, J.C. / Mackie, E.R.R. / Soares da Costa, T.P. / Humbert, P.O. / Kvansakul, M. | ||||||
履歴 |
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-構造の表示
構造ビューア | 分子: MolmilJmol/JSmol |
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-ダウンロードとリンク
-ダウンロード
PDBx/mmCIF形式 | 7qs8.cif.gz | 132.1 KB | 表示 | PDBx/mmCIF形式 |
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PDB形式 | pdb7qs8.ent.gz | 86.7 KB | 表示 | PDB形式 |
PDBx/mmJSON形式 | 7qs8.json.gz | ツリー表示 | PDBx/mmJSON形式 | |
その他 | その他のダウンロード |
-検証レポート
文書・要旨 | 7qs8_validation.pdf.gz | 437.8 KB | 表示 | wwPDB検証レポート |
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文書・詳細版 | 7qs8_full_validation.pdf.gz | 439.4 KB | 表示 | |
XML形式データ | 7qs8_validation.xml.gz | 9 KB | 表示 | |
CIF形式データ | 7qs8_validation.cif.gz | 12.1 KB | 表示 | |
アーカイブディレクトリ | https://data.pdbj.org/pub/pdb/validation_reports/qs/7qs8 ftp://data.pdbj.org/pub/pdb/validation_reports/qs/7qs8 | HTTPS FTP |
-関連構造データ
関連構造データ | 7qrsC 7qrtC 5vwiS S: 精密化の開始モデル C: 同じ文献を引用 (文献) |
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類似構造データ | 類似検索 - 機能・相同性F&H 検索 |
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非結晶学的対称性 (NCS) | NCSドメイン:
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