登録情報 | データベース: PDB / ID: 7nt7 |
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タイトル | Solution structure of toll like receptor 1 (TLR1) TIR domain |
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要素 | Toll-like receptor 1 |
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キーワード | SIGNALING PROTEIN / PROTEIN / TLR / toll like receptor / TIR domain / TLR1 |
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機能・相同性 | 機能・相同性情報
Toll-like receptor 1-Toll-like receptor 2 protein complex / detection of triacyl bacterial lipopeptide / cellular response to triacyl bacterial lipopeptide / positive regulation of toll-like receptor 2 signaling pathway / Toll Like Receptor TLR1:TLR2 Cascade / Beta defensins / Toll-like receptor 2 binding / macrophage activation / Regulation of TLR by endogenous ligand / lipopeptide binding ...Toll-like receptor 1-Toll-like receptor 2 protein complex / detection of triacyl bacterial lipopeptide / cellular response to triacyl bacterial lipopeptide / positive regulation of toll-like receptor 2 signaling pathway / Toll Like Receptor TLR1:TLR2 Cascade / Beta defensins / Toll-like receptor 2 binding / macrophage activation / Regulation of TLR by endogenous ligand / lipopeptide binding / NAD+ nucleotidase, cyclic ADP-ribose generating / MyD88 deficiency (TLR2/4) / IRAK4 deficiency (TLR2/4) / MyD88:MAL(TIRAP) cascade initiated on plasma membrane / toll-like receptor signaling pathway / positive regulation of interleukin-8 production / phagocytic vesicle membrane / transmembrane signaling receptor activity / positive regulation of interleukin-6 production / positive regulation of tumor necrosis factor production / signaling receptor activity / ER-Phagosome pathway / receptor complex / inflammatory response / immune response / membrane raft / innate immune response / SARS-CoV-2 activates/modulates innate and adaptive immune responses / Golgi apparatus / signal transduction / identical protein binding / membrane / plasma membrane類似検索 - 分子機能 Leucine rich repeat C-terminal domain / Toll-like receptor / TIR domain / Leucine-rich repeats, bacterial type / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Toll - interleukin 1 - resistance / TIR domain profile. / Toll/interleukin-1 receptor homology (TIR) domain / Toll/interleukin-1 receptor homology (TIR) domain superfamily ...Leucine rich repeat C-terminal domain / Toll-like receptor / TIR domain / Leucine-rich repeats, bacterial type / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Toll - interleukin 1 - resistance / TIR domain profile. / Toll/interleukin-1 receptor homology (TIR) domain / Toll/interleukin-1 receptor homology (TIR) domain superfamily / Leucine rich repeat / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Leucine-rich repeat profile. / Leucine-rich repeat / Leucine-rich repeat domain superfamily類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Mineev, K.S. / Lushpa, V.A. / Goncharuk, M.V. |
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資金援助 | ロシア, 1件 組織 | 認可番号 | 国 |
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Russian Foundation for Basic Research | 20-34-70024 | ロシア |
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引用 | ジャーナル: Commun Biol / 年: 2021 タイトル: Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions. 著者: Lushpa, V.A. / Goncharuk, M.V. / Lin, C. / Zalevsky, A.O. / Talyzina, I.A. / Luginina, A.P. / Vakhrameev, D.D. / Shevtsov, M.B. / Goncharuk, S.A. / Arseniev, A.S. / Borshchevskiy, V.I. / Wang, X. / Mineev, K.S. |
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履歴 | 登録 | 2021年3月9日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2021年8月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2021年9月29日 | Group: Data collection / Database references カテゴリ: citation / citation_author / pdbx_database_proc Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title |
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改定 1.2 | 2021年10月13日 | Group: Data collection / Database references / カテゴリ: citation_author / pdbx_database_proc / Item: _citation_author.identifier_ORCID |
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改定 1.3 | 2024年6月19日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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