PDB-7mk5: Crystal structure of Escherichia coli ClpP covalently inhibited b...

Basic information

• Entry: Database: PDB / ID: 7mk5
• Title: Crystal structure of Escherichia coli ClpP covalently inhibited by clipibicyclene
• Components: ATP-dependent Clp protease proteolytic subunit
• Keywords: HYDROLASE/HYDROLASE inhibitor / Inhibitor / Complex / Protease / HYDROLASE / HYDROLASE-HYDROLASE inhibitor complex

Function / homology

Function:

HslUV protease complex / endopeptidase Clp / endopeptidase Clp complex / positive regulation of programmed cell death / response to temperature stimulus / ATP-dependent peptidase activity / protein quality control for misfolded or incompletely synthesized proteins / proteasomal protein catabolic process / serine-type peptidase activity / response to radiation / ATPase binding / response to heat / serine-type endopeptidase activity / proteolysis / identical protein binding / membrane / cytosol

Domain/homology:

ClpP, Ser active site / Endopeptidase Clp serine active site. / ClpP, histidine active site / Endopeptidase Clp histidine active site. / ATP-dependent Clp protease proteolytic subunit / Clp protease proteolytic subunit /Translocation-enhancing protein TepA / Clp protease / 2-enoyl-CoA Hydratase; Chain A, domain 1 / 2-enoyl-CoA Hydratase; Chain A, domain 1 / ClpP/crotonase-like domain superfamily / Alpha-Beta Complex / Alpha Beta

Component:

ACETATE ION / Chem-ZGV / ATP-dependent Clp protease proteolytic subunit

• Biological species: Escherichia coli K-12 (bacteria)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.95 Å
• Authors: Culp, E.J. / Sychantha, D. / Hobson, C. / Pawlowski, A.J. / Prehna, G. / Wright, G.D.

Funding support

Canada, 1items

Organization	Grant number	Country
Canadian Institutes of Health Research (CIHR)	FRN-148463	Canada

• Citation: Journal: Nat Microbiol / Year: 2022; Title: ClpP inhibitors are produced by a widespread family of bacterial gene clusters.; Authors: Culp, E.J. / Sychantha, D. / Hobson, C. / Pawlowski, A.C. / Prehna, G. / Wright, G.D.

History

Deposition	Apr 21, 2021	Deposition site: RCSB / Processing site: RCSB
Revision 1.0	Feb 2, 2022	Provider: repository / Type: Initial release
Revision 1.1	Nov 16, 2022	Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.identifier_ORCID / _citation_author.name
Revision 1.2	Apr 3, 2024	Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model
Revision 1.3	Oct 30, 2024	Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature / Item: _pdbx_entry_details.has_protein_modification

Assembly

Deposited unit

A: ATP-dependent Clp protease proteolytic subunit

B: ATP-dependent Clp protease proteolytic subunit

C: ATP-dependent Clp protease proteolytic subunit

D: ATP-dependent Clp protease proteolytic subunit

E: ATP-dependent Clp protease proteolytic subunit

F: ATP-dependent Clp protease proteolytic subunit

G: ATP-dependent Clp protease proteolytic subunit

H: ATP-dependent Clp protease proteolytic subunit

I: ATP-dependent Clp protease proteolytic subunit

J: ATP-dependent Clp protease proteolytic subunit

K: ATP-dependent Clp protease proteolytic subunit

L: ATP-dependent Clp protease proteolytic subunit

M: ATP-dependent Clp protease proteolytic subunit

N: ATP-dependent Clp protease proteolytic subunit

O: ATP-dependent Clp protease proteolytic subunit

P: ATP-dependent Clp protease proteolytic subunit

Q: ATP-dependent Clp protease proteolytic subunit

R: ATP-dependent Clp protease proteolytic subunit

S: ATP-dependent Clp protease proteolytic subunit

T: ATP-dependent Clp protease proteolytic subunit

U: ATP-dependent Clp protease proteolytic subunit

V: ATP-dependent Clp protease proteolytic subunit

W: ATP-dependent Clp protease proteolytic subunit

X: ATP-dependent Clp protease proteolytic subunit

Y: ATP-dependent Clp protease proteolytic subunit

Z: ATP-dependent Clp protease proteolytic subunit

a: ATP-dependent Clp protease proteolytic subunit

b: ATP-dependent Clp protease proteolytic subunit

hetero molecules

Summary:

• 621 kDa, 28 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	620,630	116
Polymers	604,432	28
Non-polymers	16,198	88
Water	1,856	103

1

A: ATP-dependent Clp protease proteolytic subunit

B: ATP-dependent Clp protease proteolytic subunit

C: ATP-dependent Clp protease proteolytic subunit

D: ATP-dependent Clp protease proteolytic subunit

E: ATP-dependent Clp protease proteolytic subunit

F: ATP-dependent Clp protease proteolytic subunit

G: ATP-dependent Clp protease proteolytic subunit

H: ATP-dependent Clp protease proteolytic subunit

I: ATP-dependent Clp protease proteolytic subunit

J: ATP-dependent Clp protease proteolytic subunit

K: ATP-dependent Clp protease proteolytic subunit

L: ATP-dependent Clp protease proteolytic subunit

M: ATP-dependent Clp protease proteolytic subunit

N: ATP-dependent Clp protease proteolytic subunit

hetero molecules

Summary:

• defined by author&software
• Evidence: gel filtration
• 310 kDa, 14 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	310,374	59
Polymers	302,216	14
Non-polymers	8,158	45
Water	252	14

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	67090 Å2
ΔGint	-607 kcal/mol
Surface area	87590 Å2
Method	PISA

2

O: ATP-dependent Clp protease proteolytic subunit

P: ATP-dependent Clp protease proteolytic subunit

Q: ATP-dependent Clp protease proteolytic subunit

R: ATP-dependent Clp protease proteolytic subunit

S: ATP-dependent Clp protease proteolytic subunit

T: ATP-dependent Clp protease proteolytic subunit

U: ATP-dependent Clp protease proteolytic subunit

V: ATP-dependent Clp protease proteolytic subunit

W: ATP-dependent Clp protease proteolytic subunit

X: ATP-dependent Clp protease proteolytic subunit

Y: ATP-dependent Clp protease proteolytic subunit

Z: ATP-dependent Clp protease proteolytic subunit

a: ATP-dependent Clp protease proteolytic subunit

b: ATP-dependent Clp protease proteolytic subunit

hetero molecules

Summary:

• defined by author&software
• 310 kDa, 14 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	310,256	57
Polymers	302,216	14
Non-polymers	8,040	43
Water	252	14

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	65420 Å2
ΔGint	-598 kcal/mol
Surface area	87980 Å2
Method	PISA

Unit cell

Length a, b, c (Å)	94.331, 190.230, 169.884
Angle α, β, γ (deg.)	90.000, 93.612, 90.000
Int Tables number	4
Space group name H-M	P1211
Space group name Hall	P2yb

Noncrystallographic symmetry (NCS)

NCS domain:

ID	Ens-ID	Details
d_1	ens_1	(chain "A" and (resid 18 through 21 or (resid 23...
d_2	ens_1	(chain "C" and (resid 18 through 21 or (resid 23...
d_3	ens_1	(chain "D" and (resid 18 through 21 or (resid 23...
d_4	ens_1	(chain "F" and (resid 18 through 21 or (resid 23...
d_5	ens_1	(chain "G" and (resid 18 through 21 or (resid 23...
d_6	ens_1	(chain "H" and (resid 18 through 21 or (resid 23...
d_7	ens_1	(chain "I" and (resid 18 through 21 or (resid 23...
d_8	ens_1	(chain "K" and (resid 18 through 21 or (resid 23...
d_9	ens_1	(chain "L" and (resid 18 through 21 or (resid 23...
d_10	ens_1	(chain "M" and (resid 18 through 21 or (resid 23...
d_11	ens_1	(chain "N" and (resid 18 through 21 or (resid 23...
d_12	ens_1	(chain "O" and (resid 18 through 21 or (resid 23...
d_13	ens_1	(chain "P" and (resid 18 through 21 or (resid 23...
d_14	ens_1	(chain "S" and (resid 18 through 21 or (resid 23...
d_15	ens_1	(chain "T" and (resid 18 through 21 or (resid 23...
d_16	ens_1	(chain "U" and (resid 18 through 21 or (resid 23...
d_17	ens_1	(chain "V" and (resid 18 through 21 or (resid 23...
d_18	ens_1	(chain "Y" and (resid 18 through 21 or (resid 23...
d_19	ens_1	(chain "a" and (resid 18 through 21 or (resid 23...
d_20	ens_1	(chain "b" and (resid 18 through 21 or (resid 23...
d_1	ens_2	(chain "B" and (resid 18 through 21 or resid 23...
d_2	ens_2	(chain "E" and (resid 18 through 21 or resid 23...
d_3	ens_2	(chain "J" and (resid 18 through 21 or resid 23...
d_4	ens_2	(chain "Q" and (resid 18 through 21 or resid 23...
d_5	ens_2	(chain "R" and (resid 18 through 21 or resid 23...
d_6	ens_2	(chain "W" and (resid 18 through 21 or resid 23...
d_7	ens_2	(chain "X" and (resid 18 through 21 or resid 23...
d_8	ens_2	(chain "Z" and (resid 18 through 21 or resid 23...

NCS domain segments:

Dom-ID	Component-ID	Ens-ID	Beg label comp-ID	End label comp-ID	Label asym-ID	Label seq-ID
d_1	1	ens_1	ASP	SER	A	7 - 10
d_1	2	ens_1	LEU	LEU	A	12 - 13
d_1	3	ens_1	ARG	GLY	A	16 - 22
d_1	4	ens_1	VAL	PRO	A	24 - 44
d_1	5	ens_1	ASP	ILE	A	47 - 72
d_1	6	ens_1	PRO	ALA	A	74 - 85
d_1	7	ens_1	MET	ALA	A	87 - 96
d_1	8	ens_1	GLY	SER	A	98 - 106
d_1	9	ens_1	VAL	ALA	A	108 - 128
d_1	10	ens_1	GLU	LEU	A	130 - 132
d_1	11	ens_1	VAL	GLY	A	134 - 136
d_1	12	ens_1	MET	LEU	A	138 - 150
d_1	13	ens_1	GLN	GLU	A	152 - 154
d_1	14	ens_1	ASP	ASP	A	156 - 160
d_1	15	ens_1	PHE	VAL	A	162 - 169
d_1	16	ens_1	TYR	LEU	A	171 - 178
d_2	1	ens_1	ASP	SER	C	6 - 9
d_2	2	ens_1	LEU	LEU	C	11 - 12
d_2	3	ens_1	ARG	GLY	C	15 - 21
d_2	4	ens_1	VAL	PRO	C	23 - 43
d_2	5	ens_1	ASP	ILE	C	46 - 71
d_2	6	ens_1	PRO	ALA	C	73 - 84
d_2	7	ens_1	MET	ALA	C	86 - 95
d_2	8	ens_1	GLY	SER	C	97 - 105
d_2	9	ens_1	VAL	ALA	C	107 - 127
d_2	10	ens_1	GLU	LEU	C	129 - 131
d_2	11	ens_1	VAL	GLY	C	133 - 135
d_2	12	ens_1	MET	LEU	C	137 - 149
d_2	13	ens_1	GLN	GLU	C	151 - 153
d_2	14	ens_1	ASP	ASP	C	155 - 159
d_2	15	ens_1	PHE	VAL	C	161 - 168
d_2	16	ens_1	TYR	LEU	C	170 - 177
d_3	1	ens_1	ASP	SER	D	7 - 10
d_3	2	ens_1	LEU	LEU	D	12 - 13
d_3	3	ens_1	ARG	GLY	D	16 - 22
d_3	4	ens_1	VAL	PRO	D	24 - 44
d_3	5	ens_1	ASP	ILE	D	47 - 72
d_3	6	ens_1	PRO	ALA	D	74 - 85
d_3	7	ens_1	MET	ALA	D	87 - 96
d_3	8	ens_1	GLY	SER	D	98 - 106
d_3	9	ens_1	VAL	ALA	D	108 - 128
d_3	10	ens_1	GLU	LEU	D	130 - 132
d_3	11	ens_1	VAL	GLY	D	134 - 136
d_3	12	ens_1	MET	LEU	D	138 - 150
d_3	13	ens_1	GLN	GLU	D	152 - 154
d_3	14	ens_1	ASP	ASP	D	156 - 160
d_3	15	ens_1	PHE	VAL	D	162 - 169
d_3	16	ens_1	TYR	LEU	D	171 - 178
d_4	1	ens_1	ASP	SER	F	5 - 8
d_4	2	ens_1	LEU	LEU	F	10 - 11
d_4	3	ens_1	ARG	GLY	F	14 - 20
d_4	4	ens_1	VAL	PRO	F	22 - 42
d_4	5	ens_1	ASP	ILE	F	45 - 70
d_4	6	ens_1	PRO	ALA	F	72 - 83
d_4	7	ens_1	MET	ALA	F	85 - 94
d_4	8	ens_1	GLY	SER	F	96 - 104
d_4	9	ens_1	VAL	ALA	F	106 - 126
d_4	10	ens_1	GLU	LEU	F	128 - 130
d_4	11	ens_1	VAL	GLY	F	132 - 134
d_4	12	ens_1	MET	LEU	F	136 - 148
d_4	13	ens_1	GLN	GLU	F	150 - 152
d_4	14	ens_1	ASP	ASP	F	154 - 158
d_4	15	ens_1	PHE	VAL	F	160 - 167
d_4	16	ens_1	TYR	LEU	F	169 - 176
d_5	1	ens_1	ASP	SER	G	5 - 8
d_5	2	ens_1	LEU	LEU	G	10 - 11
d_5	3	ens_1	ARG	GLY	G	14 - 20
d_5	4	ens_1	VAL	PRO	G	22 - 42
d_5	5	ens_1	ASP	ILE	G	45 - 70
d_5	6	ens_1	PRO	ALA	G	72 - 83
d_5	7	ens_1	MET	ALA	G	85 - 94
d_5	8	ens_1	GLY	SER	G	96 - 104
d_5	9	ens_1	VAL	ALA	G	106 - 126
d_5	10	ens_1	GLU	LEU	G	128 - 130
d_5	11	ens_1	VAL	GLY	G	132 - 134
d_5	12	ens_1	MET	LEU	G	136 - 148
d_5	13	ens_1	GLN	GLU	G	150 - 152
d_5	14	ens_1	ASP	ASP	G	154 - 158
d_5	15	ens_1	PHE	VAL	G	160 - 167
d_5	16	ens_1	TYR	LEU	G	169 - 176
d_6	1	ens_1	ASP	SER	H	2 - 5
d_6	2	ens_1	LEU	LEU	H	7 - 8
d_6	3	ens_1	ARG	GLY	H	11 - 17
d_6	4	ens_1	VAL	PRO	H	19 - 39
d_6	5	ens_1	ASP	ILE	H	42 - 67
d_6	6	ens_1	PRO	ALA	H	69 - 80
d_6	7	ens_1	MET	ALA	H	82 - 91
d_6	8	ens_1	GLY	SER	H	93 - 101
d_6	9	ens_1	VAL	ALA	H	103 - 123
d_6	10	ens_1	GLU	LEU	H	125 - 127
d_6	11	ens_1	VAL	GLY	H	129 - 131
d_6	12	ens_1	MET	LEU	H	133 - 145
d_6	13	ens_1	GLN	GLU	H	147 - 149
d_6	14	ens_1	ASP	ASP	H	151 - 155
d_6	15	ens_1	PHE	VAL	H	157 - 164
d_6	16	ens_1	TYR	LEU	H	166 - 173
d_7	1	ens_1	ASP	SER	I	6 - 9
d_7	2	ens_1	LEU	LEU	I	11 - 12
d_7	3	ens_1	ARG	GLY	I	15 - 21
d_7	4	ens_1	VAL	PRO	I	23 - 43
d_7	5	ens_1	ASP	ILE	I	46 - 71
d_7	6	ens_1	PRO	ALA	I	73 - 84
d_7	7	ens_1	MET	ALA	I	86 - 95
d_7	8	ens_1	GLY	SER	I	97 - 105
d_7	9	ens_1	VAL	ALA	I	107 - 127
d_7	10	ens_1	GLU	LEU	I	129 - 131
d_7	11	ens_1	VAL	GLY	I	133 - 135
d_7	12	ens_1	MET	LEU	I	137 - 149
d_7	13	ens_1	GLN	GLU	I	151 - 153
d_7	14	ens_1	ASP	ASP	I	155 - 159
d_7	15	ens_1	PHE	VAL	I	161 - 168
d_7	16	ens_1	TYR	LEU	I	170 - 177
d_8	1	ens_1	ASP	SER	K	4 - 7
d_8	2	ens_1	LEU	LEU	K	9 - 10
d_8	3	ens_1	ARG	GLY	K	13 - 19
d_8	4	ens_1	VAL	PRO	K	21 - 41
d_8	5	ens_1	ASP	ILE	K	44 - 69
d_8	6	ens_1	PRO	ALA	K	71 - 82
d_8	7	ens_1	MET	ALA	K	84 - 93
d_8	8	ens_1	GLY	SER	K	95 - 103
d_8	9	ens_1	VAL	ALA	K	105 - 125
d_8	10	ens_1	GLU	LEU	K	127 - 129
d_8	11	ens_1	VAL	GLY	K	131 - 133
d_8	12	ens_1	MET	LEU	K	135 - 147
d_8	13	ens_1	GLN	GLU	K	149 - 151
d_8	14	ens_1	ASP	ASP	K	153 - 157
d_8	15	ens_1	PHE	VAL	K	159 - 166
d_8	16	ens_1	TYR	LEU	K	168 - 175
d_9	1	ens_1	ASP	SER	L	5 - 8
d_9	2	ens_1	LEU	LEU	L	10 - 11
d_9	3	ens_1	ARG	GLY	L	14 - 20
d_9	4	ens_1	VAL	PRO	L	22 - 42
d_9	5	ens_1	ASP	ILE	L	45 - 70
d_9	6	ens_1	PRO	ALA	L	72 - 83
d_9	7	ens_1	MET	ALA	L	85 - 94
d_9	8	ens_1	GLY	SER	L	96 - 104
d_9	9	ens_1	VAL	ALA	L	106 - 126
d_9	10	ens_1	GLU	LEU	L	128 - 130
d_9	11	ens_1	VAL	GLY	L	132 - 134
d_9	12	ens_1	MET	LEU	L	136 - 148
d_9	13	ens_1	GLN	GLU	L	150 - 152
d_9	14	ens_1	ASP	ASP	L	154 - 158
d_9	15	ens_1	PHE	VAL	L	160 - 167
d_9	16	ens_1	TYR	LEU	L	169 - 176
d_10	1	ens_1	ASP	SER	M	5 - 8
d_10	2	ens_1	LEU	LEU	M	10 - 11
d_10	3	ens_1	ARG	GLY	M	14 - 20
d_10	4	ens_1	VAL	PRO	M	22 - 42
d_10	5	ens_1	ASP	ILE	M	45 - 70
d_10	6	ens_1	PRO	ALA	M	72 - 83
d_10	7	ens_1	MET	ALA	M	85 - 94
d_10	8	ens_1	GLY	SER	M	96 - 104
d_10	9	ens_1	VAL	ALA	M	106 - 126
d_10	10	ens_1	GLU	LEU	M	128 - 130
d_10	11	ens_1	VAL	GLY	M	132 - 134
d_10	12	ens_1	MET	LEU	M	136 - 148
d_10	13	ens_1	GLN	GLU	M	150 - 152
d_10	14	ens_1	ASP	ASP	M	154 - 158
d_10	15	ens_1	PHE	VAL	M	160 - 167
d_10	16	ens_1	TYR	LEU	M	169 - 176
d_11	1	ens_1	ASP	SER	N	6 - 9
d_11	2	ens_1	LEU	LEU	N	11 - 12
d_11	3	ens_1	ARG	GLY	N	15 - 21
d_11	4	ens_1	VAL	PRO	N	23 - 43
d_11	5	ens_1	ASP	ILE	N	46 - 71
d_11	6	ens_1	PRO	ALA	N	73 - 84
d_11	7	ens_1	MET	ALA	N	86 - 95
d_11	8	ens_1	GLY	SER	N	97 - 105
d_11	9	ens_1	VAL	ALA	N	107 - 127
d_11	10	ens_1	GLU	LEU	N	129 - 131
d_11	11	ens_1	VAL	GLY	N	133 - 135
d_11	12	ens_1	MET	LEU	N	137 - 149
d_11	13	ens_1	GLN	GLU	N	151 - 153
d_11	14	ens_1	ASP	ASP	N	155 - 159
d_11	15	ens_1	PHE	VAL	N	161 - 168
d_11	16	ens_1	TYR	LEU	N	170 - 177
d_12	1	ens_1	ASP	SER	O	6 - 9
d_12	2	ens_1	LEU	LEU	O	11 - 12
d_12	3	ens_1	ARG	GLY	O	15 - 21
d_12	4	ens_1	VAL	PRO	O	23 - 43
d_12	5	ens_1	ASP	ILE	O	46 - 71
d_12	6	ens_1	PRO	ALA	O	73 - 84
d_12	7	ens_1	MET	ALA	O	86 - 95
d_12	8	ens_1	GLY	SER	O	97 - 105
d_12	9	ens_1	VAL	ALA	O	107 - 127
d_12	10	ens_1	GLU	LEU	O	129 - 131
d_12	11	ens_1	VAL	GLY	O	133 - 135
d_12	12	ens_1	MET	LEU	O	137 - 149
d_12	13	ens_1	GLN	GLU	O	151 - 153
d_12	14	ens_1	ASP	ASP	O	155 - 159
d_12	15	ens_1	PHE	VAL	O	161 - 168
d_12	16	ens_1	TYR	LEU	O	170 - 177
d_13	1	ens_1	ASP	SER	P	7 - 10
d_13	2	ens_1	LEU	LEU	P	12 - 13
d_13	3	ens_1	ARG	GLY	P	16 - 22
d_13	4	ens_1	VAL	PRO	P	24 - 44
d_13	5	ens_1	ASP	ILE	P	47 - 72
d_13	6	ens_1	PRO	ALA	P	74 - 85
d_13	7	ens_1	MET	ALA	P	87 - 96
d_13	8	ens_1	GLY	SER	P	98 - 106
d_13	9	ens_1	VAL	ALA	P	108 - 128
d_13	10	ens_1	GLU	LEU	P	130 - 132
d_13	11	ens_1	VAL	GLY	P	134 - 136
d_13	12	ens_1	MET	LEU	P	138 - 150
d_13	13	ens_1	GLN	GLU	P	152 - 154
d_13	14	ens_1	ASP	ASP	P	156 - 160
d_13	15	ens_1	PHE	VAL	P	162 - 169
d_13	16	ens_1	TYR	LEU	P	171 - 178
d_14	1	ens_1	ASP	SER	S	6 - 9
d_14	2	ens_1	LEU	LEU	S	11 - 12
d_14	3	ens_1	ARG	GLY	S	15 - 21
d_14	4	ens_1	VAL	PRO	S	23 - 43
d_14	5	ens_1	ASP	ILE	S	46 - 71
d_14	6	ens_1	PRO	ALA	S	73 - 84
d_14	7	ens_1	MET	ALA	S	86 - 95
d_14	8	ens_1	GLY	SER	S	97 - 105
d_14	9	ens_1	VAL	ALA	S	107 - 127
d_14	10	ens_1	GLU	LEU	S	129 - 131
d_14	11	ens_1	VAL	GLY	S	133 - 135
d_14	12	ens_1	MET	LEU	S	137 - 149
d_14	13	ens_1	GLN	GLU	S	151 - 153
d_14	14	ens_1	ASP	ASP	S	155 - 159
d_14	15	ens_1	PHE	VAL	S	161 - 168
d_14	16	ens_1	TYR	LEU	S	170 - 177
d_15	1	ens_1	ASP	SER	T	5 - 8
d_15	2	ens_1	LEU	LEU	T	10 - 11
d_15	3	ens_1	ARG	GLY	T	14 - 20
d_15	4	ens_1	VAL	PRO	T	22 - 42
d_15	5	ens_1	ASP	ILE	T	45 - 70
d_15	6	ens_1	PRO	ALA	T	72 - 83
d_15	7	ens_1	MET	ALA	T	85 - 94
d_15	8	ens_1	GLY	SER	T	96 - 104
d_15	9	ens_1	VAL	ALA	T	106 - 126
d_15	10	ens_1	GLU	LEU	T	128 - 130
d_15	11	ens_1	VAL	GLY	T	132 - 134
d_15	12	ens_1	MET	LEU	T	136 - 148
d_15	13	ens_1	GLN	GLU	T	150 - 152
d_15	14	ens_1	ASP	ASP	T	154 - 158
d_15	15	ens_1	PHE	VAL	T	160 - 167
d_15	16	ens_1	TYR	LEU	T	169 - 176
d_16	1	ens_1	ASP	SER	U	5 - 8
d_16	2	ens_1	LEU	LEU	U	10 - 11
d_16	3	ens_1	ARG	GLY	U	14 - 20
d_16	4	ens_1	VAL	PRO	U	22 - 42
d_16	5	ens_1	ASP	ILE	U	45 - 70
d_16	6	ens_1	PRO	ALA	U	72 - 83
d_16	7	ens_1	MET	ALA	U	85 - 94
d_16	8	ens_1	GLY	SER	U	96 - 104
d_16	9	ens_1	VAL	ALA	U	106 - 126
d_16	10	ens_1	GLU	LEU	U	128 - 130
d_16	11	ens_1	VAL	GLY	U	132 - 134
d_16	12	ens_1	MET	LEU	U	136 - 148
d_16	13	ens_1	GLN	GLU	U	150 - 152
d_16	14	ens_1	ASP	ASP	U	154 - 158
d_16	15	ens_1	PHE	VAL	U	160 - 167
d_16	16	ens_1	TYR	LEU	U	169 - 176
d_17	1	ens_1	ASP	SER	V	6 - 9
d_17	2	ens_1	LEU	LEU	V	11 - 12
d_17	3	ens_1	ARG	GLY	V	15 - 21
d_17	4	ens_1	VAL	PRO	V	23 - 43
d_17	5	ens_1	ASP	ILE	V	46 - 71
d_17	6	ens_1	PRO	ALA	V	73 - 84
d_17	7	ens_1	MET	ALA	V	86 - 95
d_17	8	ens_1	GLY	SER	V	97 - 105
d_17	9	ens_1	VAL	ALA	V	107 - 127
d_17	10	ens_1	GLU	LEU	V	129 - 131
d_17	11	ens_1	VAL	GLY	V	133 - 135
d_17	12	ens_1	MET	LEU	V	137 - 149
d_17	13	ens_1	GLN	GLU	V	151 - 153
d_17	14	ens_1	ASP	ASP	V	155 - 159
d_17	15	ens_1	PHE	VAL	V	161 - 168
d_17	16	ens_1	TYR	LEU	V	170 - 177
d_18	1	ens_1	ASP	SER	Y	5 - 8
d_18	2	ens_1	LEU	LEU	Y	10 - 11
d_18	3	ens_1	ARG	GLY	Y	14 - 20
d_18	4	ens_1	VAL	PRO	Y	22 - 42
d_18	5	ens_1	ASP	ILE	Y	45 - 70
d_18	6	ens_1	PRO	ALA	Y	72 - 83
d_18	7	ens_1	MET	ALA	Y	85 - 94
d_18	8	ens_1	GLY	SER	Y	96 - 104
d_18	9	ens_1	VAL	ALA	Y	106 - 126
d_18	10	ens_1	GLU	LEU	Y	128 - 130
d_18	11	ens_1	VAL	GLY	Y	132 - 134
d_18	12	ens_1	MET	LEU	Y	136 - 148
d_18	13	ens_1	GLN	GLU	Y	150 - 152
d_18	14	ens_1	ASP	ASP	Y	154 - 158
d_18	15	ens_1	PHE	VAL	Y	160 - 167
d_18	16	ens_1	TYR	LEU	Y	169 - 176
d_19	1	ens_1	ASP	SER	AA	4 - 7
d_19	2	ens_1	LEU	LEU	AA	9 - 10
d_19	3	ens_1	ARG	GLY	AA	13 - 19
d_19	4	ens_1	VAL	PRO	AA	21 - 41
d_19	5	ens_1	ASP	ILE	AA	44 - 69
d_19	6	ens_1	PRO	ALA	AA	71 - 82
d_19	7	ens_1	MET	ALA	AA	84 - 93
d_19	8	ens_1	GLY	SER	AA	95 - 103
d_19	9	ens_1	VAL	ALA	AA	105 - 125
d_19	10	ens_1	GLU	LEU	AA	127 - 129
d_19	11	ens_1	VAL	GLY	AA	131 - 133
d_19	12	ens_1	MET	LEU	AA	135 - 147
d_19	13	ens_1	GLN	GLU	AA	149 - 151
d_19	14	ens_1	ASP	ASP	AA	153 - 157
d_19	15	ens_1	PHE	VAL	AA	159 - 166
d_19	16	ens_1	TYR	LEU	AA	168 - 175
d_20	1	ens_1	ASP	SER	BA	6 - 9
d_20	2	ens_1	LEU	LEU	BA	11 - 12
d_20	3	ens_1	ARG	GLY	BA	15 - 21
d_20	4	ens_1	VAL	PRO	BA	23 - 43
d_20	5	ens_1	ASP	ILE	BA	46 - 71
d_20	6	ens_1	PRO	ALA	BA	73 - 84
d_20	7	ens_1	MET	ALA	BA	86 - 95
d_20	8	ens_1	GLY	SER	BA	97 - 105
d_20	9	ens_1	VAL	ALA	BA	107 - 127
d_20	10	ens_1	GLU	LEU	BA	129 - 131
d_20	11	ens_1	VAL	GLY	BA	133 - 135
d_20	12	ens_1	MET	LEU	BA	137 - 149
d_20	13	ens_1	GLN	GLU	BA	151 - 153
d_20	14	ens_1	ASP	ASP	BA	155 - 159
d_20	15	ens_1	PHE	VAL	BA	161 - 168
d_20	16	ens_1	TYR	LEU	BA	170 - 177
d_1	1	ens_2	ASP	SER	B	7 - 10
d_1	2	ens_2	LEU	LEU	B	12 - 13
d_1	3	ens_2	ARG	GLY	B	16 - 22
d_1	4	ens_2	VAL	PRO	B	24 - 44
d_1	5	ens_2	LYS	ALA	B	46 - 85
d_1	6	ens_2	MET	ALA	B	87 - 96
d_1	7	ens_2	GLY	ALA	B	98 - 128
d_1	8	ens_2	GLU	LEU	B	130 - 150
d_1	9	ens_2	GLN	GLU	B	152 - 154
d_1	10	ens_2	ASP	ASP	B	156 - 160
d_1	11	ens_2	PHE	VAL	B	162 - 169
d_1	12	ens_2	TYR	THR	B	171 - 179
d_2	1	ens_2	ASP	SER	E	7 - 10
d_2	2	ens_2	LEU	LEU	E	12 - 13
d_2	3	ens_2	ARG	GLY	E	16 - 22
d_2	4	ens_2	VAL	PRO	E	24 - 44
d_2	5	ens_2	LYS	ALA	E	46 - 85
d_2	6	ens_2	MET	ALA	E	87 - 96
d_2	7	ens_2	GLY	ALA	E	98 - 128
d_2	8	ens_2	GLU	LEU	E	130 - 150
d_2	9	ens_2	GLN	GLU	E	152 - 154
d_2	10	ens_2	ASP	ASP	E	156 - 160
d_2	11	ens_2	PHE	VAL	E	162 - 169
d_2	12	ens_2	TYR	THR	E	171 - 179
d_3	1	ens_2	ASP	SER	J	6 - 9
d_3	2	ens_2	LEU	LEU	J	11 - 12
d_3	3	ens_2	ARG	GLY	J	15 - 21
d_3	4	ens_2	VAL	PRO	J	23 - 43
d_3	5	ens_2	LYS	ALA	J	45 - 84
d_3	6	ens_2	MET	ALA	J	86 - 95
d_3	7	ens_2	GLY	ALA	J	97 - 127
d_3	8	ens_2	GLU	LEU	J	129 - 149
d_3	9	ens_2	GLN	GLU	J	151 - 153
d_3	10	ens_2	ASP	ASP	J	155 - 159
d_3	11	ens_2	PHE	VAL	J	161 - 168
d_3	12	ens_2	TYR	THR	J	170 - 178
d_4	1	ens_2	ASP	SER	Q	8 - 11
d_4	2	ens_2	LEU	LEU	Q	13 - 14
d_4	3	ens_2	ARG	GLY	Q	17 - 23
d_4	4	ens_2	VAL	PRO	Q	25 - 45
d_4	5	ens_2	LYS	ALA	Q	47 - 86
d_4	6	ens_2	MET	ALA	Q	88 - 97
d_4	7	ens_2	GLY	ALA	Q	99 - 129
d_4	8	ens_2	GLU	LEU	Q	131 - 151
d_4	9	ens_2	GLN	GLU	Q	153 - 155
d_4	10	ens_2	ASP	ASP	Q	157 - 161
d_4	11	ens_2	PHE	VAL	Q	163 - 170
d_4	12	ens_2	TYR	THR	Q	172 - 180
d_5	1	ens_2	ASP	SER	R	7 - 10
d_5	2	ens_2	LEU	LEU	R	12 - 13
d_5	3	ens_2	ARG	GLY	R	16 - 22
d_5	4	ens_2	VAL	PRO	R	24 - 44
d_5	5	ens_2	LYS	ALA	R	46 - 85
d_5	6	ens_2	MET	ALA	R	87 - 96
d_5	7	ens_2	GLY	ALA	R	98 - 128
d_5	8	ens_2	GLU	LEU	R	130 - 150
d_5	9	ens_2	GLN	GLU	R	152 - 154
d_5	10	ens_2	ASP	ASP	R	156 - 160
d_5	11	ens_2	PHE	VAL	R	162 - 169
d_5	12	ens_2	TYR	THR	R	171 - 179
d_6	1	ens_2	ASP	SER	W	1 - 4
d_6	2	ens_2	LEU	LEU	W	6 - 7
d_6	3	ens_2	ARG	GLY	W	10 - 16
d_6	4	ens_2	VAL	PRO	W	18 - 38
d_6	5	ens_2	LYS	ALA	W	40 - 79
d_6	6	ens_2	MET	ALA	W	81 - 90
d_6	7	ens_2	GLY	ALA	W	92 - 122
d_6	8	ens_2	GLU	LEU	W	124 - 144
d_6	9	ens_2	GLN	GLU	W	146 - 148
d_6	10	ens_2	ASP	ASP	W	150 - 154
d_6	11	ens_2	PHE	VAL	W	156 - 163
d_6	12	ens_2	TYR	THR	W	165 - 173
d_7	1	ens_2	ASP	SER	X	6 - 9
d_7	2	ens_2	LEU	LEU	X	11 - 12
d_7	3	ens_2	ARG	GLY	X	15 - 21
d_7	4	ens_2	VAL	PRO	X	23 - 43
d_7	5	ens_2	LYS	ALA	X	45 - 84
d_7	6	ens_2	MET	ALA	X	86 - 95
d_7	7	ens_2	GLY	ALA	X	97 - 127
d_7	8	ens_2	GLU	LEU	X	129 - 149
d_7	9	ens_2	GLN	GLU	X	151 - 153
d_7	10	ens_2	ASP	ASP	X	155 - 159
d_7	11	ens_2	PHE	VAL	X	161 - 168
d_7	12	ens_2	TYR	THR	X	170 - 178
d_8	1	ens_2	ASP	SER	Z	5 - 8
d_8	2	ens_2	LEU	LEU	Z	10 - 11
d_8	3	ens_2	ARG	GLY	Z	14 - 20
d_8	4	ens_2	VAL	PRO	Z	22 - 42
d_8	5	ens_2	LYS	ALA	Z	44 - 83
d_8	6	ens_2	MET	ALA	Z	85 - 94
d_8	7	ens_2	GLY	ALA	Z	96 - 126
d_8	8	ens_2	GLU	LEU	Z	128 - 148
d_8	9	ens_2	GLN	GLU	Z	150 - 152
d_8	10	ens_2	ASP	ASP	Z	154 - 158
d_8	11	ens_2	PHE	VAL	Z	160 - 167
d_8	12	ens_2	TYR	THR	Z	169 - 177

NCS ensembles :

ID
ens_1
ens_2

Components

#1: Protein

A B C D E F G H I J K L M N O P Q R S ...
ATP-dependent Clp protease proteolytic subunit / Caseinolytic protease / Endopeptidase Clp / Heat shock protein F21.5 / Protease Ti

Details:

Mass: 21586.863 Da / Num. of mol.: 28
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Escherichia coli K-12 (bacteria) / Strain: K12 / Gene: clpP, lopP, b0437, JW0427 / Production host: Escherichia coli BL21(DE3) (bacteria) / References: UniProt: P0A6G7, endopeptidase Clp

#2: Chemical

A-301 A-302 B-301 B-302 C-301 D-301 D-302 D-303 E-301 F-401 F-402 F-404 G-301 H-301 H-303 I-301 I-303 J-301 J-303 K-301 ...
ChemComp-MPD / (4S)-2-METHYL-2,4-PENTANEDIOL

Details:

Mass: 118.174 Da / Num. of mol.: 50 / Source method: obtained synthetically / Formula: C₆H₁₄O₂ / Comment: precipitant*YM

#3: Chemical

A-303 B-303 C-303 F-403 G-302 L-501 P-204 R-302 X-202 Z-303
ChemComp-ACT / ACETATE ION

Details:

Mass: 59.044 Da / Num. of mol.: 10 / Source method: obtained synthetically / Formula: C₂H₃O₂

#4: Chemical

A-304 B-304 C-302 D-304 E-302 F-405 G-303 H-302 I-302 J-302 K-302 L-503 M-302 N-303 O-303 P-203 Q-303 R-303 S-203 T-203 ...
ChemComp-ZGV / 4-[(1E)-3-{[(2E,4E,6E,8S)-8-hydroxy-4-methyldeca-2,4,6-trienoyl]amino}-3-oxoprop-1-en-1-yl]azete-1(2H)-carboxylic acid

Details:

Mass: 346.378 Da / Num. of mol.: 28 / Source method: obtained synthetically / Formula: C₁₈H₂₂N₂O₅ / Feature type: SUBJECT OF INVESTIGATION

#5: Water

ChemComp-HOH / water

Details:

Mass: 18.015 Da / Num. of mol.: 103 / Source method: isolated from a natural source / Formula: H₂O

• Has ligand of interest: Y
• Has protein modification: Y

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 2.34 ų/Da / Density % sol: 47.45 %
• Crystal grow: Temperature: 293 K / Method: vapor diffusion, hanging drop / pH: 5.6 / Details: 0.1 M sodium acetate, 30% MPD

Data collection

• Diffraction: Mean temperature: 100 K / Serial crystal experiment: N
• Diffraction source: Source: SYNCHROTRON / Site: CLSI / Beamline: 08B1-1 / Wavelength: 0.97895 Å
• Detector: Type: RAYONIX MX-300 / Detector: CCD / Date: Feb 5, 2021
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 0.97895 Å / Relative weight: 1
• Reflection: Resolution: 2.95→45.41 Å / Num. obs: 125212 / % possible obs: 99.71 % / Redundancy: 3.9 % / B_iso Wilson estimate: 60.71 Ų / CC_1/2: 0.988 / R_merge(I) obs: 0.175 / R_pim(I) all: 0.102 / Net I/σ(I): 6.9
• Reflection shell: Resolution: 2.95→3.055 Å / R_merge(I) obs: 1.25 / Mean I/σ(I) obs: 1.2 / Num. unique obs: 12429 / CC_1/2: 0.423 / R_pim(I) all: 0.72 / % possible all: 99.7

Processing

Software

Name	Version	Classification
PHENIX	1.19.1_4122	refinement
PDB_EXTRACT	3.27	data extraction
XDS		data reduction
XDS		data scaling
PHENIX		phasing

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: ITYF

Resolution: 2.95→45.41 Å / SU ML: 0.4229 / Cross valid method: FREE R-VALUE / σ(F): 1.35 / Phase error: 26.0871
Stereochemistry target values: GeoStd + Monomer Library + CDL v1.2

	Rfactor	Num. reflection	% reflection
Rfree	0.2479	6042	4.83 %
Rwork	0.2106	119116	-
obs	0.2124	125158	99.74 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
• Displacement parameters: B_iso mean: 56.79 Ų

Refinement step

Cycle: LAST / Resolution: 2.95→45.41 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	39239	0	857	103	40199

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.01	40664
X-RAY DIFFRACTION	f_angle_d	1.2671	54794
X-RAY DIFFRACTION	f_chiral_restr	0.0489	6174
X-RAY DIFFRACTION	f_plane_restr	0.0248	7014
X-RAY DIFFRACTION	f_dihedral_angle_d	14.946	15507

Refine LS restraints NCS

Ens-ID	Dom-ID	Auth asym-ID	Refine-ID	Type	Rms dev position (Å)
ens_1	d_2	A	X-RAY DIFFRACTION	Torsion NCS	0.633409487144
ens_1	d_3	A	X-RAY DIFFRACTION	Torsion NCS	0.577092359886
ens_1	d_4	A	X-RAY DIFFRACTION	Torsion NCS	0.557991302773
ens_1	d_5	A	X-RAY DIFFRACTION	Torsion NCS	0.599819598206
ens_1	d_6	A	X-RAY DIFFRACTION	Torsion NCS	0.560760980354
ens_1	d_7	A	X-RAY DIFFRACTION	Torsion NCS	0.58105511465
ens_1	d_8	A	X-RAY DIFFRACTION	Torsion NCS	0.49225064457
ens_1	d_9	A	X-RAY DIFFRACTION	Torsion NCS	0.532646022897
ens_1	d_10	A	X-RAY DIFFRACTION	Torsion NCS	0.600083004638
ens_1	d_11	A	X-RAY DIFFRACTION	Torsion NCS	0.526508912821
ens_1	d_12	A	X-RAY DIFFRACTION	Torsion NCS	0.532951855245
ens_1	d_13	A	X-RAY DIFFRACTION	Torsion NCS	0.548013740682
ens_1	d_14	A	X-RAY DIFFRACTION	Torsion NCS	0.579318975473
ens_1	d_15	A	X-RAY DIFFRACTION	Torsion NCS	0.565027762168
ens_1	d_16	A	X-RAY DIFFRACTION	Torsion NCS	0.571576218042
ens_1	d_17	A	X-RAY DIFFRACTION	Torsion NCS	0.570299702054
ens_1	d_18	A	X-RAY DIFFRACTION	Torsion NCS	0.512285044772
ens_1	d_19	A	X-RAY DIFFRACTION	Torsion NCS	0.557201611791
ens_1	d_20	A	X-RAY DIFFRACTION	Torsion NCS	0.551001513396
ens_2	d_2	G	X-RAY DIFFRACTION	Torsion NCS	0.569234518695
ens_2	d_3	G	X-RAY DIFFRACTION	Torsion NCS	0.509944264632
ens_2	d_4	G	X-RAY DIFFRACTION	Torsion NCS	0.602005374677
ens_2	d_5	G	X-RAY DIFFRACTION	Torsion NCS	0.557496862516
ens_2	d_6	G	X-RAY DIFFRACTION	Torsion NCS	0.577641928503
ens_2	d_7	G	X-RAY DIFFRACTION	Torsion NCS	0.551632510436
ens_2	d_8	G	X-RAY DIFFRACTION	Torsion NCS	0.571584883303

LS refinement shell

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Refine-ID	% reflection obs (%)
2.95-2.98	0.3595	204	0.3243	3913	X-RAY DIFFRACTION	99.78
2.98-3.02	0.3253	193	0.3198	3984	X-RAY DIFFRACTION	99.57
3.02-3.06	0.358	199	0.3024	3930	X-RAY DIFFRACTION	99.76
3.06-3.09	0.3218	207	0.2935	3936	X-RAY DIFFRACTION	99.74
3.09-3.13	0.3348	210	0.2982	3991	X-RAY DIFFRACTION	99.74
3.13-3.18	0.3282	216	0.2978	3913	X-RAY DIFFRACTION	99.78
3.18-3.22	0.313	214	0.289	3968	X-RAY DIFFRACTION	99.79
3.22-3.27	0.3775	224	0.2917	4020	X-RAY DIFFRACTION	99.79
3.27-3.32	0.3124	180	0.2851	3935	X-RAY DIFFRACTION	99.69
3.32-3.38	0.3028	197	0.2674	3968	X-RAY DIFFRACTION	99.83
3.38-3.43	0.3253	212	0.2535	3926	X-RAY DIFFRACTION	99.93
3.43-3.5	0.3182	177	0.2471	4016	X-RAY DIFFRACTION	99.83
3.5-3.56	0.2949	198	0.2363	3933	X-RAY DIFFRACTION	99.9
3.56-3.64	0.274	193	0.2239	4006	X-RAY DIFFRACTION	99.74
3.64-3.72	0.2948	187	0.2378	3958	X-RAY DIFFRACTION	99.88
3.72-3.8	0.2848	211	0.2311	3965	X-RAY DIFFRACTION	99.93
3.8-3.9	0.2575	211	0.2074	3963	X-RAY DIFFRACTION	99.93
3.9-4	0.2104	204	0.1933	3962	X-RAY DIFFRACTION	99.83
4-4.12	0.2385	219	0.1879	3983	X-RAY DIFFRACTION	99.76
4.12-4.25	0.2199	224	0.1766	3960	X-RAY DIFFRACTION	99.95
4.25-4.41	0.1842	187	0.1649	3953	X-RAY DIFFRACTION	99.83
4.41-4.58	0.1771	209	0.156	3955	X-RAY DIFFRACTION	99.88
4.58-4.79	0.1866	212	0.1584	3976	X-RAY DIFFRACTION	99.86
4.79-5.04	0.2208	204	0.178	3973	X-RAY DIFFRACTION	99.76
5.04-5.36	0.2325	205	0.1898	3975	X-RAY DIFFRACTION	99.74
5.36-5.77	0.2201	153	0.2021	4034	X-RAY DIFFRACTION	99.76
5.77-6.35	0.2554	192	0.2077	4006	X-RAY DIFFRACTION	99.6
6.35-7.27	0.241	181	0.193	4025	X-RAY DIFFRACTION	99.67
7.27-9.14	0.2037	202	0.177	3993	X-RAY DIFFRACTION	99.76
9.14-45.41	0.1893	217	0.1724	3996	X-RAY DIFFRACTION	98.39

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	6.21902292074	0.906078892012	0.567331762886	2.19920891559	1.76296944546	1.99228615318	0.313253918928	0.64109494099	0.00271123926325	-0.456842679701	0.0315948386163	0.0488815249781	-0.0215237102699	0.178916905717	0.32622072963	0.753484254712	0.0830137558072	0.00270899851133	0.594289288469	-0.0924269899893	0.541328434719	11.96	64.48	78.503
2	3.63471987395	-0.257263700179	0.601865447027	7.00736844628	-6.00346646897	5.21581350854	0.556539891392	0.061950659965	0.109954366687	-0.0472166861778	-0.722793228162	0.885253831117	-0.185087896956	-0.342792449962	-0.205194609262	0.567992182525	0.0458626929038	0.0932325199117	0.427278703696	-0.135384424085	0.43477126103	8.961	56.392	87.638
3	4.29582566123	2.1211849514	2.75871885407	6.55749608692	-0.935472017599	2.94300768377	-0.0762333250005	0.0184105086912	0.0804840747892	-0.262371302321	-0.319456864659	0.0528274436057	0.124511148694	-0.180034916944	0.357883475597	0.507445311396	-0.0893514064675	0.0955232764582	0.584648027962	-0.178836320686	0.345434789842	15.697	57.261	92.746
4	6.06251601923	0.665211044518	1.88333217323	1.1270340596	-2.12631150346	5.73656271851	0.034164748739	-0.798483572209	0.390921128382	0.345091377803	0.0131500546429	-0.141616517867	-0.236443100884	-0.570196960837	0.00434438728392	0.448849400894	-0.0167506727357	0.0153266495436	0.463353941023	-0.168127970998	0.376437622346	8.292	54.205	95.995
5	6.68020152781	0.581575791615	2.66896077074	2.28870424777	-1.02218709469	1.58283748593	0.0112709015751	-0.672737306297	0.60279363332	0.11130860806	-0.213816618199	0.676078995732	0.195297631078	-0.485175742403	0.194556531013	0.52030136159	0.0403724658821	0.0584098885068	0.643707116293	-0.232667186079	0.44385480257	0.698	53.676	95.266
6	2.81277643754	-2.446107573	1.93798183326	4.49077561197	-0.597818369953	1.01187263351	0.979692719492	-0.170958471168	-0.0210270449721	-1.43160798193	-0.720123214428	0.28954093223	0.626116463567	0.00691300889547	-0.183490649399	0.547254912812	-0.0797588419785	0.0958558911575	0.537728239528	0.00220009626837	0.333516008684	3.711	35.959	92.074
7	6.53018817109	-7.52332569296	-3.3282338969	8.56792907566	3.748621732	2.54257623208	-0.034228688521	-1.16938505833	-0.126839356105	-0.341648887775	0.221372497509	-0.146400357956	-0.141486234684	0.111936007649	-0.313077185966	0.426166159278	-0.106603048229	0.0865287421222	0.585802747944	-0.000242719649336	0.445088052185	8.548	34.641	103.91
8	9.69564286718	-1.06644229836	2.71206073819	7.48074297873	0.438623909829	9.55716508251	-0.990630470043	-0.777120904542	-1.24903473589	0.152950915174	-0.0587291040271	0.836175196662	0.0849937607784	-2.5268221416	1.07223864782	0.591205534682	-0.0885329309709	0.16688509508	0.911847549012	-0.0941016011357	0.622251333903	-6.068	38.046	104.53
9	7.44604296213	-8.61276193713	3.85887736694	9.93568781798	-4.62714552399	2.09959255012	-0.62029136957	-1.89735449482	0.420880278317	0.848787666277	1.26955136667	0.37652131341	-0.204245209105	-0.523476339678	-0.772629454149	0.480103489808	-0.0812411787192	0.178500225649	0.763339073888	-0.127147315754	0.589902065726	-9.019	41.675	94.443
10	2.55156449401	1.5964383484	2.52010075646	2.52501778013	-0.455912126599	8.35024807456	0.296839178318	-0.969734381918	0.965193821922	-0.533001067495	0.153147243364	0.350674790917	-1.07103059664	-0.986806338189	-0.191013445366	0.666458796778	0.034325805443	0.180352052251	0.718547736739	-0.426096167944	0.916272605646	-8.88	59.003	91.668
11	5.00461857628	-0.0389259397577	0.926128284474	3.17873973356	2.99537523933	5.16240924097	0.161645276506	0.328165363937	0.255170001077	-0.0840228369372	-0.104652430809	-0.175397692723	-0.345394477745	-0.289693655737	-0.104249693389	0.458510144853	-0.059472887007	0.109463275995	0.433514993207	-0.00436599129091	0.32886268881	28.979	55.495	93.263
12	0.710605422194	-1.22986641065	-0.672157564079	1.36012860343	0.259306321041	1.95931381049	0.0256661182924	-0.191484658901	0.0631242987049	0.16293299176	0.0952872761082	-0.0786995574331	-0.138039582573	0.348255349962	-0.147030447121	0.413344564939	-0.105652625055	0.0730635365037	0.517908870905	-0.0615992589936	0.354224099159	30.629	43.362	100.889
13	2.21837023558	-2.41074808898	-1.71359428384	3.91523941484	1.85889710926	3.16585268557	0.0192955194556	-0.737581217718	0.12802385553	0.384813129556	0.133548099222	-0.0745876273998	-0.00107138044543	0.43311458365	-0.133696345736	0.63727393587	-0.123674808461	-0.0321212125785	0.616219031603	-0.014553961275	0.343583524464	31.402	35.067	106.317
14	3.75508294328	-1.61828178674	-0.69575089174	7.30214568706	0.713292652786	5.39742561102	0.163394759681	0.00555298502734	0.0318722469744	-0.0425605694602	0.164561408466	0.278205193463	-0.523571955734	-0.148811611872	-0.208043401161	0.330918665168	0.00376481538281	-0.0122155261188	0.378009174703	-0.0144832923053	0.301916595882	43.977	55.032	81.259
15	2.39460392607	-0.108595371615	-0.390278423919	2.52740659983	2.5271367727	2.73864236286	0.0402958490505	-0.0651249414734	0.195959586014	0.0381416414578	-0.178515867695	0.159419695998	0.122288254728	0.173546860296	0.0682700802795	0.315934484002	-0.0318720280292	-0.0177739884717	0.301300981564	0.00597410494494	0.395726207472	51.747	42.901	83.059
16	1.09668143956	0.474943840978	1.00702248784	3.50133487638	2.86128695937	6.77371214921	0.0935462869679	-0.229731517289	-0.173539101191	0.416294936419	0.0824529207057	-0.303871442255	0.264910335057	0.51464862566	-0.295890737056	0.381043191562	-0.0199268474788	-0.0922305617338	0.474339297273	0.0365313256798	0.515571009924	57.374	34.284	84.237
17	1.45113925089	-1.9308232269	-1.50639607538	2.68228364293	2.30845264601	7.69055015157	0.19934207438	-1.47744435247	1.18209961632	-0.59010641004	-0.0852879055674	1.14330591208	-0.262181963906	-0.365863419244	-0.33536270181	0.584418817687	-0.028127562901	-0.151603056266	0.840134897695	-0.27310839882	0.740812806401	40.639	62.5	71.884
18	5.73918420602	-0.369112515852	1.30916612067	2.79551840011	0.662346995343	5.74076778449	-0.337231004307	0.105706459774	0.454318441999	0.000612162040832	-0.158371113315	0.280913729083	-0.420418157868	-0.151647144543	0.265401166603	0.354318123528	-0.106143596128	0.0176018934358	0.303963261337	0.0557693099607	0.459467335491	43.143	56.43	58.751
19	5.08021372856	-1.05006320508	1.44021953657	2.23512914986	0.79356501492	4.53961316103	-0.171992610643	0.016831126111	0.609022954587	-0.074949223306	0.401982501572	0.807077558592	-0.235981193372	0.20647500024	0.147095838536	0.388114599214	-0.0379502812008	0.00574107770443	0.404840661469	-0.0386410042598	0.425833457081	50.613	56.081	60.239
20	3.93009844937	-1.12664867544	2.88486421943	3.3018170317	-0.915660677695	4.97576210065	-0.0758436789416	0.58365624881	0.35199498161	-0.120915992184	-0.0317753088611	-0.439318814727	-0.37981201789	0.701720977769	0.138924275727	0.418029839632	-0.120521495729	0.0963777627197	0.37934237489	0.0338239669942	0.436253445052	52.769	51.266	55.917
21	2.37912651482	1.39914520373	5.05271797765	0.935810554196	2.64871830186	9.54695380616	0.539717116865	-0.4681621426	-0.183918926524	0.243946185471	-0.409766434193	-0.157108093322	0.756339938502	-0.587122946479	-0.224869965998	0.485073879269	-0.0172815878103	0.107818927964	0.346011867034	0.017065992415	0.503562535095	47.994	34.993	54.961
22	2.83564439652	8.06130925143	4.59100165129	8.68054036195	3.8929109921	4.75650241189	-0.246549705392	0.218398233774	0.403956032304	-0.157097780987	0.153856562214	0.103525184533	-0.204466287262	0.649930828549	0.0768373535117	0.346405419	0.00346486376142	0.072563762371	0.587723155843	-0.0827115389275	0.475071333839	49.112	37.456	42.409
23	5.10098812108	5.17471592818	4.7030046604	5.86792389691	6.57175508498	8.41604302506	0.205833506227	0.728928638074	-0.385923949869	-0.179748424746	0.624799527239	-0.754769121907	0.121705676174	0.907024989216	-0.911994397545	0.405941775103	0.0883001205013	0.0881072540439	0.427376326039	0.0276851311174	0.619185272972	61.719	36.584	54.934
24	1.9290543179	-1.76482350834	-0.63219512016	3.96662057788	4.0513881082	5.4134447494	0.813666769652	-0.249516626254	-0.219369769407	0.975189454939	1.00024699177	-1.53679466758	0.508489132675	0.312306142751	-1.22617467588	0.514978137476	-0.195167908493	0.032991271123	0.451247862069	0.146189041116	0.976142398173	62.785	51.723	66.618
25	4.91185057852	0.443348601772	6.75096493713	0.0818641212174	0.621166380889	9.26178952464	-0.64068214631	-0.885663496139	-0.484827958522	-0.0624266570957	0.229140709938	0.603426396349	-0.51821995116	-1.21189610549	0.498816621587	0.572085568844	-0.0130954643725	0.0579085696195	0.570993925344	-0.0430792303496	0.718023913777	34.617	64.138	59.669
26	1.59233795251	0.721848570994	0.725913476248	1.3917734331	1.10968214	1.52108406063	0.0635352765504	0.0713001125656	0.19849450869	-0.206850935438	-0.0567764638872	0.00353771947728	-0.253541665136	-0.0453993225621	-0.0083685320055	0.514084219083	-0.0552911555346	0.0368133283786	0.341999329084	0.0586494242611	0.391993496741	29.49	55.295	42.508
27	8.7519511786	6.25062004141	-3.83359406018	6.67723827039	-3.34883894643	2.67202656662	-0.249061345441	0.505970331739	-0.0938811040808	-0.695989071881	-0.0724446674169	-0.197152105597	0.189218622819	-0.0434011392361	0.307691414221	0.64059140551	0.0298958721598	0.1667577456	0.50849289203	0.00205245016335	0.272196113863	22.603	43.128	29.299
28	2.05173405001	1.0265786799	2.24676343253	3.6491920965	3.09978062811	5.07401148352	-0.237871037632	0.751960897306	0.0610892145385	-0.541925855815	0.615801939798	-0.688273954612	-0.764034635085	0.818834697585	-0.219324777032	0.50294364397	-0.065665802471	0.145578720954	0.538890515733	0.105538196846	0.58290652748	42.339	49.703	35.068
29	4.67740472075	4.83102292921	3.01933475388	5.10262745046	3.38367937444	4.76339495505	0.0521038859951	-0.296065292822	0.289290572574	0.959388441641	-0.713023492977	-1.4289151563	-0.228570623455	1.02847309095	0.708268481898	0.699443374516	-0.126248389477	0.0201592140463	0.559085765923	0.193882196643	0.526093817005	21.105	66.496	56.801
30	5.86458735082	-1.20010817796	-0.0194394372422	3.20013848658	1.82544200526	6.04787598524	0.214681864677	-0.144906925412	0.131920567879	-0.245403777529	-0.0509163659122	0.265839084169	-0.393522900368	-0.0737745129109	-0.160674514939	0.417996564922	-0.011632774522	-0.100839181038	0.292297878013	-0.0434103165398	0.396657820207	5.964	61.703	52.097
31	3.48961891967	-1.65425204739	-1.91803421943	0.862052339855	0.66966422008	6.10709586834	0.210516393759	-0.7210418952	-0.912951214739	-0.90262120461	-0.510953822715	-0.311816461773	0.661678358978	-0.610051797462	0.319007269562	0.465153690511	-0.00265108474504	-0.113220471266	0.341639629976	0.0215049044213	0.527316543968	6.957	52.817	43.969
32	3.04909906226	1.80947156907	-1.53084024026	1.84183577741	-0.462433893305	1.30741419984	-0.225664635682	0.0753522089895	-0.0914680462198	-0.558220460724	-0.0764507689322	-0.0324221048653	0.0110718402491	0.1090411465	0.319104225055	0.492525949979	-0.00382591863866	-0.143329000816	0.325167288538	-0.0289185077408	0.323344539975	3.994	49.451	43.465
33	2.87310100657	2.79949854176	-2.70410971215	2.57738607683	-6.17585475538	4.99295015556	-0.239534743399	0.243442669426	0.166535091625	-0.085476721854	0.153908467623	0.170568181304	-0.163370811753	-0.717312814065	0.0417719706605	0.550383759853	0.00354058144679	-0.0836224398633	0.371936095107	-0.108553903899	0.418255232704	-9.372	44.425	48.49
34	5.47522248614	-0.659891112803	-6.19151225145	4.38809135692	-2.05716198928	8.91199070507	-0.0282787569904	1.25277322728	-0.544332981013	-1.60944070185	0.300773233466	-0.452830153865	0.953646927802	-1.77955540521	-0.197153931168	0.787926595623	0.0341439925195	-0.29953035337	0.506638737216	0.086232349661	0.799738461616	-6.368	47.339	34.3
35	8.38170598377	5.52522623458	-5.11714433777	6.47120252027	-3.88609606565	5.22773243088	-0.73389135078	0.810230160084	0.114784931929	-0.683554915746	0.84974033424	0.146865294814	-0.214923433025	-1.46881430852	-0.134481959915	0.730509267799	-0.0059414672132	-0.00397399834405	0.56737121193	0.134417255383	0.333023015385	4.952	47.937	33.278
36	3.14710269055	2.29776224542	2.61372509125	2.26274298387	3.51123019759	6.7865624133	-0.164138080417	0.277462429191	1.6732950712	0.0630158130597	0.147186903474	0.126208011458	-1.61626998656	0.605660855586	-0.0835977317148	1.01393677475	0.0564496045487	-0.120588015559	0.472016270684	0.184889084362	0.583099597799	12.465	63.783	34.313
37	7.59411792464	1.90775120719	5.77968964111	9.19570820621	1.59013933733	9.29526152428	0.186462350964	1.11800054484	1.25450697715	-0.495506940846	-0.158786625152	-1.42113485845	-1.28011186439	1.68175382882	0.0427964527932	0.609118678155	-0.214963326171	-0.0146317752381	0.642046173964	0.0601436918907	0.622237498699	11.048	65.943	65.665
38	4.12301387152	-1.10419018346	-0.914333877191	7.30407620475	0.756799363553	6.64797922642	-0.073345141768	-0.381173934779	0.465156177118	0.310885450944	0.0298421760785	-0.292786702762	-0.375243592203	0.138511615352	0.132050461146	0.321884170876	0.00573602831752	-0.0378869764033	0.409128345997	-0.126219318513	0.451482068337	-1.853	60.225	73.994
39	5.34847207763	-1.04342375468	-1.08185593506	8.75419746067	0.298978758775	8.98848444261	-0.143261632815	-0.453148920266	-0.0558320282491	-0.184713430545	0.552866605247	0.343337346603	-0.32803354058	0.0548805037128	-0.304527933315	0.355726393831	0.0121153096304	-0.0987081175325	0.387258177033	-0.160618024002	0.668343900652	-9.659	56.377	66.518
40	1.90024340311	-1.7675646677	0.919045520282	3.40291246847	-4.29557958883	4.73822611326	-0.101624748851	-0.131105487409	-0.0338258328802	-0.283360782245	0.256248119495	0.146809418325	0.398731813595	-0.442990654128	-0.26549119963	0.436076212352	-0.113501005534	0.00694308319272	0.441199048247	-0.00324302375185	0.396512580047	-7.481	40.49	69.558
41	8.80101207915	-8.61605769306	5.97201311638	7.52923770391	-4.78837885404	4.79228562489	-0.245075635073	-0.331732610428	0.232619799128	0.0938827682244	0.0161086918906	-0.10485599298	-0.190344762811	-0.72782149101	0.324408894505	0.279691050928	-0.00576559427683	-0.0177725822227	0.599365591301	-0.0329118202475	0.524684119224	-13.633	40.798	80.726
42	2.07404016346	-6.92317479429	4.60867588325	4.91282506272	-2.17220160387	8.60550880452	-0.723223185738	-0.57917526044	-0.0105851385549	-0.839858561301	1.1088418	0.58428960538	0.14956107163	-1.06825802826	-0.575910616999	0.39516720628	-0.109606919088	-0.0078050350436	0.642479441995	0.0435990927312	0.536523670329	-22.708	45.455	69.854
43	0.655295603359	-2.67623181441	1.74306492894	2.07555133079	-7.38782340751	5.29131692808	0.21323969879	0.00541446083111	0.295501646556	0.014277535744	-0.350851659789	1.18482901347	0.235885517701	0.0836582519817	-0.0241263988894	0.626948894645	0.0522262525518	-0.182527091765	0.526132248182	-0.134222537024	0.612450330189	-16.598	47.14	60.924
44	5.91906446349	1.25478991385	-4.96067930788	1.22184491744	-0.948971429864	4.25259495297	1.25148705706	0.963825208969	0.440370475897	-0.375366461606	-0.0293856715714	1.11203863921	-1.09093070325	-0.607960768912	-1.16973955019	0.532824929162	0.101371026273	-0.18461206388	0.559784771821	-0.0237678162615	0.777793610165	-12.312	62.691	58.137
45	9.08250096678	0.60417858592	-2.97877754542	3.68073735867	1.17485215177	1.53385820684	-0.350597407796	0.95507458076	-1.07526554587	-0.749440969153	0.352932082659	-1.60316305375	2.24736962499	-0.171453557955	-0.0328177636674	0.923960165647	-0.222762663446	-0.0710896966517	0.544081005333	-0.150359264055	0.742571059966	22.593	-14.334	78.228
46	4.8574628309	-0.635966451153	1.15608642526	2.97894855292	-0.946040969204	3.93414721051	0.104436752959	-0.383892464496	-0.672245657988	-0.357934638126	0.119825369319	0.357052616383	0.232409926566	-0.0602915807822	-0.214464865807	0.541733914845	-0.137156694222	-0.0771100272267	0.457869745453	0.099100882435	0.384425089035	18.094	-6.852	87.495
47	0.922887214842	-1.18557635256	0.101418644069	2.69669951467	0.764628854434	0.480955829542	0.373242672265	-0.403878721994	-0.150054957177	1.00855093419	-0.131459092177	-0.0526981341485	-0.084883259186	-0.34445666181	-0.112323515639	0.537060385183	-0.18821772902	-0.154701472559	0.495588383097	0.0931831878431	0.550064913445	15.905	-5.24	95.162
48	3.59257196428	1.01961214021	-0.145103401749	3.70738814708	-1.49131695593	1.32712140211	0.589853975651	-0.398738710469	0.383471564755	-0.534789248508	-0.343117600948	-0.132230989725	0.647548376772	-0.0449050493791	-0.251098239418	0.583257426138	-0.0932554628273	-0.0651145685586	0.486148002824	0.0533003267258	0.42166215097	25.199	1.594	94.192
49	1.53494581287	-0.925877206533	-0.453292495005	2.54132346554	1.10993276458	0.349233100588	0.179780522218	-0.122534802007	0.00850947599186	0.139747572229	0.0244874251364	-0.290522234017	0.175122695157	0.0369949842767	-0.244633385495	0.578680642824	-0.100656986622	-0.0548926097492	0.506024339539	0.0823215486709	0.349414078309	24.15	5.349	96.439
50	5.94336003726	-4.47367903034	4.34796094992	7.45449266265	-2.06779168749	1.53781910022	0.060287641003	-0.830288691615	-0.092400664965	0.184373433914	0.176854765331	-0.026056777997	0.349313807962	-0.601764144208	-0.223206492101	0.568174755191	-0.151952496111	-0.0216125876493	0.710496009957	0.0826927074102	0.287524885016	16.036	11.034	105.045
51	9.77219196435	-7.10505403698	-1.31822476249	4.94629443601	1.06797063686	0.36106370682	-0.153275323571	-1.02935942728	0.00316013583501	0.797627456108	0.435148072934	-0.443028864015	0.295986888072	-0.103822762219	-0.123314336629	0.565688546384	-0.201204957197	-0.117601805798	0.661751297103	0.0984420998549	0.426128665651	32.576	6.295	102.426
52	4.05780017789	-0.682376285287	-0.637999552235	7.04334840299	1.8302411344	2.33907033778	-0.0977370269804	-0.729744581976	-0.439044894727	0.489582946036	0.421838129434	-0.800215243938	0.681539531858	0.236142427991	0.0802450679909	0.580269503419	-0.0521038650902	-0.146099293307	0.806436405812	0.384630790346	0.791659396639	34.873	-10.347	96.908
53	2.81782214489	4.48136200017	0.143778177253	7.32286587312	-0.391145301867	2.42617453077	-0.0254386633225	0.933437891539	-0.743431499384	-1.02037181952	-0.00106740804148	-0.538480184899	1.56648860274	-1.21179968551	-0.0684547445309	0.647822434751	-0.0411885465816	-0.0215936011219	0.715207108124	-0.0585698779835	0.680600487604	31.469	-11.761	63.949
54	3.77617359293	1.47631081594	-3.34160232642	4.1757251745	-0.287891477595	4.49141222743	0.00469005400225	-0.054751319427	-0.328041807527	0.166744401204	0.00896641380438	-0.118753010761	0.28141227801	-0.0151554861664	0.0117225302761	0.444774243341	-0.00962178702873	-0.167766007422	0.296317642485	0.0163605300678	0.462474241153	40.431	-6.499	78.186
55	3.78455435893	-2.99062861367	-3.14327341743	3.0287133609	2.86836178373	2.77283753446	-0.303904041921	-0.0235386126683	-0.0028507318497	0.373406148145	0.269588255476	-0.0989586594552	0.75266036404	-0.136946392697	-0.0821523952346	0.553640833405	-0.0498914773655	-0.155534425446	0.387257202715	0.0320970187244	0.510565111532	44.055	11.909	80.835
56	4.02649052997	-4.39464162538	-3.84255022172	5.07592372552	3.15703733132	3.38651829642	0.19413591941	-0.50881869567	0.0908350725938	0.394372708872	0.0211297668565	-0.621846596665	0.302641992931	0.318436044056	-0.151882360768	0.497377791747	-0.0393089539643	-0.193649886533	0.495024320728	0.00408301675206	0.515603957263	47.753	8.564	91.772
57	3.541879784	-0.244744492782	-2.57061593196	0.0858841971017	0.0507147092358	1.77446665114	0.193923563626	-0.349866513833	-0.078651455005	-0.732863003717	0.859954642974	-0.621034464522	0.0209215830563	0.255599792887	-1.05209650125	0.535963774952	-0.106927531787	-0.0679398485227	0.432405003675	-0.0383701624445	0.662213722782	56.63	6.368	76.911
58	8.91357350091	6.28190390653	6.97434479376	5.7279968337	4.24030375657	5.58588190348	1.09479421535	0.742122064796	-1.2246460701	0.266912263816	0.91712746795	-2.45981667729	1.48335675415	0.684834541337	-1.85332089458	0.562680951294	0.127910454638	-0.146986573083	0.480810710864	-0.0712651742681	1.19047248272	54.523	-9.283	69.236
59	4.84488334071	3.15342186647	1.5527563795	6.06783591012	-2.16845807635	8.56551272049	0.876158112477	-0.550783022684	-1.00259474538	-0.794894771518	-0.460328638161	0.387737287104	0.260437022084	-1.70428471553	-0.553959955572	0.51616443573	-0.196971014196	0.0394382861759	0.758236280359	-0.0604992036506	0.721920307384	25.642	-9.328	51.596
60	5.73351807203	-0.32009576256	3.02424451419	7.86951942437	-1.87433883301	8.89360796503	0.0776461001969	-0.283058614696	-0.192087468297	0.128952713683	0.189652870322	0.270017743532	0.120142984157	-0.39304560354	-0.145301762914	0.376005522538	-0.00163095923145	0.106948990209	0.337108787571	0.00655547543414	0.453220600718	37.947	-5.559	57.396
61	2.89172751543	2.34577704443	-0.296695660243	3.40496479068	-0.455915245367	5.19381058487	0.0369564578687	-0.0987631487885	-0.251183270616	0.0854653094553	-0.186302616648	-0.418415775385	0.379626593054	0.245662240931	0.126302611857	0.303465490801	0.0280057001231	0.014120306782	0.411744374484	-0.0349523408987	0.486895613879	45.204	-2.611	53.171
62	1.58937551897	1.52321325792	3.38250722664	2.61009057508	3.06044563261	5.92985435446	-0.365571708517	0.0876565695954	-0.079752577623	-0.0718522210001	-0.429836303429	0.527490822834	-0.132240618135	-0.0473034426829	0.667899234449	0.231328106263	0.0255072437557	0.0981482588049	0.437091788635	0.00610935067404	0.538288337566	47.661	8.294	51.542
63	0.882558969372	-1.09009243003	-0.502778090914	8.29626210808	7.78810475262	5.72001503676	-0.0368429500077	0.165982001484	-0.154797661661	0.0809655869276	0.361724224443	-0.41343407498	0.280811615928	0.278187734374	-0.30431253637	0.316025337512	-0.0659792148602	0.0282101270691	0.488091239065	-0.0768257786	0.6510058471	56.262	11.649	63.309
64	6.95959792668	-6.299196853	2.77070318069	9.04874028322	0.212605364361	3.42166883489	-0.529524141836	1.09926757776	-0.793141447056	-0.787045009753	0.474131500908	-0.306196972596	-1.00911106974	1.18839342827	-0.0321278690425	0.486605867332	-0.0835023584581	0.214197118153	0.468489612511	-0.108937762965	0.671432137005	61.366	11.804	49.148
65	0.62932649409	1.62130222401	2.19886416148	6.06166308851	7.55171246677	9.23602118202	-0.188789431171	0.0706984605734	-0.204698894891	0.0305394973007	0.596802076588	-0.35548122418	0.152251114072	0.930552540177	-0.376704625912	0.431592214936	0.0231160588309	0.0273948295329	0.587919928301	0.0584787304749	0.466980113028	51.969	11.698	42.669
66	4.01077972209	0.386287950875	-0.517816763794	2.75446078926	0.132102357649	3.04952730219	0.323300782639	0.737699172631	-0.617438905919	-0.197126920886	-0.0908479683369	-0.418868295005	0.747844282028	0.181098039182	-0.220558066935	0.539798312246	0.0714746725606	0.081934301489	0.369381311742	-0.100394631601	0.632832174328	45.614	-3.503	37.033
67	7.02104664141	2.29631188907	3.07826869796	6.53887598787	-2.08571545505	4.08891841451	0.558049685558	-0.700710644117	-1.06322201681	-0.474705473723	-0.692963125825	0.469084795334	0.655861893134	-0.227067677035	-0.297244656081	0.452630135234	-0.0880693833695	-0.0258370354236	0.446333793326	-0.0314098032936	0.720422279448	14.213	-7.138	46.457
68	5.51269840794	0.349227442009	1.21998732186	1.92836610797	-2.32209243419	3.40218700888	0.0432935814203	0.177517555214	-0.449615986855	0.0227429645842	-0.0100669334949	0.133127063285	0.218110986215	0.202674404256	-0.00145938336165	0.349874785845	0.0139260964265	0.0529670293388	0.32301727058	-0.15421377416	0.493974759218	26.343	0.911	37.938
69	6.03346890706	2.8285540208	1.32638932575	1.46274244313	0.561499794037	0.657503741875	0.151777527963	0.706807513658	0.391530294466	0.385329790754	-0.08441904064	0.391248600189	0.372586104316	0.149077754613	-0.0813502603458	0.464300882927	0.146867271548	-0.0222359477733	0.406079091984	-0.0738189678033	0.412234283136	26.47	13.564	33.712
70	5.37769104764	3.69663830866	6.2290866111	5.11359096335	5.2857788896	8.70855187674	-0.189023964833	0.553972588347	0.319667851161	-0.185417702887	-0.323524960047	0.154383159594	0.131087485023	0.387604911219	0.437346520052	0.316287538973	-0.0202806435644	0.0643923477388	0.525337037245	-0.0305028115952	0.389493509394	40.937	17.626	34.981
71	8.78366933952	4.40465255565	1.74415206512	7.48821284033	2.91944310761	2.47080930154	-0.216198802569	1.36028852708	0.058735607214	-0.82022731286	0.349963192734	0.14116539975	-0.163718818133	0.630487824626	-0.100254719979	0.553548281779	0.012178003813	-0.00765716282402	0.518475166421	0.0570072076141	0.35396418452	26.68	18.485	24.077
72	6.9551162629	6.62444946855	-6.10996195671	9.87723305196	-7.27750868821	5.85978996585	-0.308806223669	1.23286807237	-1.16113841363	0.421253586067	0.686838130193	-0.63003140068	0.837573197932	-0.415970018918	-0.312576860418	0.632847708392	7.56121692373E-5	-0.103459931527	0.700621459122	-0.0465034660878	0.503218378625	15.169	3.121	24.202
73	2.82851944147	2.72439423989	-2.84696943897	3.14893398275	-0.986097671232	8.04311077399	1.06583977172	-0.78122877707	-2.20730080447	0.484465865937	-0.741950636776	0.695566567205	0.967572582925	0.3394758741	0.19795427276	0.571037614728	-0.0332300699352	-0.146644021717	0.651520086144	0.187347994069	1.12406290832	1.996	-6.779	54.132
74	8.33392850477	0.966954856985	-1.99637585195	5.87518187933	-2.80647119409	9.7179771153	0.503250041514	0.405986318527	-0.829963983537	0.725789220076	-0.391343103185	0.064770084055	0.0580100231189	-0.103009837412	0.0306100341111	0.334673316513	0.026341374794	-0.11977400776	0.273213860628	0.0126833768253	0.562563997738	2.427	3.279	46.159
75	8.06653248503	-2.84375168892	-2.74906269361	6.71936946847	-0.405261670095	3.27703500619	-0.103135810056	0.00611854433279	-0.184445373869	0.0325831289981	0.0483360454847	-0.117044352158	0.0501274176658	0.0386696895122	0.0107243830085	0.351816408399	0.0136813187678	-0.116399737702	0.3100569193	-0.0758539918016	0.448649855324	2.843	3.759	39.154
76	3.48655569572	2.75493762119	-2.0539908281	2.42229362864	-1.23728764619	1.93798080168	0.443042787815	0.0153423627366	-0.242711586936	0.457059061429	-0.34285280697	-0.156543196938	-0.357434913119	0.0746348996259	-0.0844531165129	0.465766868572	0.0902373883099	-0.137775253061	0.344803049815	0.00503437873892	0.530225071616	-1.079	16.554	39.526
77	9.88814794359	7.75905989157	4.0775671251	7.80634113197	2.27369297729	1.87597822416	0.140613265088	0.513459268766	-0.711015649018	-0.215891512405	0.200653325095	-0.239835440464	0.607262641371	0.0557554843103	-0.373750015091	0.555633564575	-0.0314464185563	-0.0540214044956	0.393953691463	-0.101651862089	0.40787106934	8.775	22.616	29.985
78	5.23190915439	3.6551125006	3.22855893164	6.23107528719	7.14453745008	8.87875606936	0.18556331612	0.266835287724	-0.333113804236	0.409658630814	0.114680186769	-0.377064827687	-0.6354520503	-0.72530202928	-0.264170127899	0.514307105261	-0.0219379841263	-0.0809204835313	0.5575658704	-0.0675046809845	0.455733308428	-5.979	23.619	28.445
79	9.03967741394	6.56362152575	-2.67874032608	5.0536535316	-2.31246476308	2.85571096833	0.325874249495	1.48211411961	0.962057039157	0.327938235138	0.678659887661	1.39512369894	0.39687628958	0.528184141618	-0.921177784533	0.478195794774	0.099910578173	-0.109573553421	0.40761592397	-0.0304686765609	0.575484024344	-10.559	20.603	38.311
80	5.97452728038	3.07950384758	1.1187545269	4.71906279734	-1.82553627445	8.92946447862	0.948159081587	-0.0340885195676	0.303235730128	0.23853484154	-0.299701993192	0.788296463386	1.1551577421	-0.00870760915611	-0.821757208874	0.527655173169	0.0878861174713	-0.0869171916338	0.376614927005	-0.0425521745215	0.608482046087	-14.919	5.136	40.693
81	7.14502713486	-0.382242894286	5.84574284627	8.8640488772	0.183974083974	4.77504917112	0.251094811505	1.88726446837	-0.408873973107	1.72133455484	-0.108420174871	-1.15133869824	1.52097410031	2.4157881653	-0.485076500485	0.661441506266	0.177534529991	-0.00663139849176	0.91214419399	0.104893192735	0.605904978575	0.947	-8.186	67.699
82	3.83900125581	-1.91328174249	-0.622174599554	2.94758483462	0.586942340439	3.59282061367	-0.0742737468564	0.189500575124	-0.0712154162498	-0.232648291988	0.0407046039788	-0.0937505690995	0.34128786115	-0.193229356557	-0.00881087660062	0.409931281033	-0.0980583338266	-0.0606168828844	0.375958652849	0.0171235602171	0.371891714263	-10.063	1.24	59.036
83	4.93220821545	-1.74129718381	2.05527666499	1.78988370746	0.581571645873	7.77127408701	0.321369635998	-0.296797467787	-0.365640731809	0.0695349592795	-0.28504527954	-0.626384946274	-0.528484956924	0.135489003358	-0.142469013343	0.312761219941	-0.151602512801	-8.05998026214E-5	0.484616324015	-0.0121378214463	0.446817238639	-13.348	10.756	65.893
84	0.421683193832	1.9000560054	0.201974149205	6.06721698207	-4.12351363643	4.43477088763	0.142915473497	-0.353592232312	-0.354200388123	0.360822341152	-0.377899628706	-0.593008805627	-0.269018134949	-0.0519329212088	0.226378389098	0.401715125463	-0.0538250693416	0.0158309630033	0.356566059576	-0.0380224621031	0.592203173397	-14.24	14.919	64.625
85	6.78852811748	5.44671238441	-2.4667289804	4.47521783957	-2.233033598	1.22336269788	-0.106272795838	0.392758609677	-0.0175396340207	-0.28236636093	0.226106023954	0.212173916289	0.065251284294	-0.762558739365	-0.116663496553	0.34833848201	0.00805590800382	-0.103182845424	0.554155491318	-0.0630733389012	0.461403826273	-18.726	22.669	54.966
86	1.66569338837	0.95794929165	-0.842927683549	6.30870282865	-2.68255648663	1.41224187162	0.572734833392	-0.405024361574	0.205099250228	1.08581372345	-0.579531590103	1.15665524421	-0.238497991979	0.273616677065	0.0359745652715	0.47585355156	-0.169534778971	0.120319635459	0.707612936966	-0.0929523661379	0.480803159242	-21.265	11.279	72.555
87	7.16027986122	0.262469816461	-3.79457604264	6.8394673403	-1.01039548145	6.87261151181	0.195108170975	1.02406366943	-0.659678882273	-1.18612396314	-0.509523650222	-0.305845465868	0.528861092293	-0.424313469224	0.354425896594	0.918263146997	0.0516516781893	-0.191980127388	0.521373733417	-0.031786541717	0.47046261191	9.357	-11.907	77.405
88	6.30225075489	-0.733455707191	1.8008584241	3.10928610301	0.330649790188	6.26517208615	0.607151618458	0.32330750875	0.14688811614	-0.169512535754	-0.203275765501	0.247560452397	0.608904693846	-0.114251240674	-0.3391357046	0.47955832128	-0.142773255534	0.00372944863283	0.482092028395	0.0607224117936	0.289032833759	-1.471	-2.302	77.477
89	5.23434746085	-0.996665398085	1.34830654219	0.422319041186	0.345804505202	5.85934588962	0.454284993768	-0.576534979445	-0.476090092151	0.291095714469	-0.263754013593	0.241424127908	0.491630685666	-0.439906587327	-0.354747297611	0.410333746643	-0.1072215501	-0.00853343971167	0.469808386137	0.109625479441	0.374320217138	-2.289	-4.484	85.016
90	1.88692051034	-2.40774381932	1.92837856742	4.24928978734	-1.34151469432	5.87711948476	0.414265152506	-0.247945782879	-0.138729017958	-0.340749387528	-0.172966944072	0.652119696712	1.18502287454	-0.829478928106	-0.276531638295	0.472584755764	-0.218258735096	-0.0123320823334	0.568344313966	-0.0121275123423	0.471630524266	-8.734	-0.267	83.264
91	2.22600938385	-2.06211023304	2.75980974889	3.95369029378	-1.67215326662	5.39486656343	-0.192887021697	-0.276239732459	-0.309017034586	0.374615700156	0.235048034876	0.134176319937	0.253816288975	-1.03333826935	-0.0502762791325	0.478053474984	-0.142519199835	0.0394838878418	0.466133834279	0.0262620085204	0.27921316704	-2.907	1.79	91.856
92	3.33693874637	-5.3845986377	4.34322372129	8.27624921194	-5.35035450865	4.58963888716	-0.0113185688378	0.0854668627649	0.453651600544	0.39629180835	-0.458384107348	-0.580380098463	-0.131681401384	0.49179129431	0.49650950212	0.38778926193	-0.142545175219	0.00176484400554	0.664984398652	0.0330069579121	0.42530678424	-1.537	17.246	87.317
93	1.92266806096	1.23680794775	0.491120523555	3.62501283325	-4.08907874143	5.10110564539	-0.096803833405	-0.331924104898	-0.140835217799	0.0671082799092	0.357528510254	0.438386030321	0.0983224306125	-0.992561580667	-0.125141481081	0.40595902497	-0.023003648964	0.094614331588	0.653695456661	-0.0363943404516	0.379228059733	-14.03	18.454	84.41
94	3.59182392641	1.64120296	-0.755735608468	9.47339619688	-8.38607983386	7.63753152753	0.0632551420848	-1.29024259672	0.905250877997	2.25631985665	0.0592949929594	0.474973380086	-1.65423454573	-0.856214208599	-0.0761161346432	0.774555117926	-0.262943905369	0.18937776839	0.972693464747	-0.032065450945	0.628562355485	-12.57	14.943	98.794
95	3.21642759228	-4.77601017826	4.9291018626	7.17151723996	-6.68259015159	7.63415256972	-0.42265167255	-0.58157737679	-0.088808136598	1.4965212293	1.03503414157	0.358859322527	-0.229391085996	-0.957955273399	-0.725861036214	0.705980317231	-0.143846136076	0.0621429970513	0.678800022777	-0.0063660643994	0.374858417744	-2.018	11.311	100.194
96	1.68029632267	2.55271638795	0.223735797205	3.91135159635	1.12160851186	5.38461645457	0.710526796311	-0.17129155995	-0.166490276408	0.487523430226	-0.26839175026	0.0168610245714	1.05652012705	-0.172767722772	-0.506560727978	0.770008872353	-0.261018916466	-0.0659945309248	0.764214595406	0.0975856917479	0.358058755902	0.615	-4.988	99.211
97	4.74334408958	1.97042045759	1.8229243725	7.06091538754	-3.59811896385	7.43886577778	0.47571045276	-0.363060743953	0.0345659973586	0.426767446187	-0.473611002905	0.0176176433715	-0.18289641135	0.963416369844	0.0946304858522	0.336169697327	-0.105236305983	0.124241612804	0.488725708456	-0.00631632167966	0.488924936588	35.982	-2.379	147.155
98	4.1389557385	-1.63296674959	-0.745081942752	4.43582844652	1.55448517528	6.44384692354	-0.0370815520899	0.0213086953536	-0.442288864637	-0.0965088737686	-0.016560063207	-0.0729365711162	0.575381698845	0.00049268267464	0.0896149248684	0.374603861495	-0.0677772596855	-0.0156512535888	0.332965861761	0.0552630307028	0.387992558997	30.996	1.579	136
99	6.15878591676	0.723294214925	-3.86290095649	5.3745635453	-0.978254029444	2.50001888582	-0.292510183356	0.0582758213088	0.155839547967	-0.193763091857	-0.699844292317	-0.561525780624	-0.386846339722	1.20450543331	-0.30675198762	0.463304638669	-0.101135302149	0.0601045942125	0.326648409673	0.0185600148032	0.413114355741	26.496	11.703	141.969
100	2.51657198372	2.92800605881	-1.25618863925	4.49020711037	-3.82436636354	4.7596299244	0.212563725542	-0.0920425526564	-0.0119768848116	0.509093407033	-0.144076681998	0.0274049328823	-0.580640043584	-0.226175264931	-0.0337309126468	0.232559566179	0.0279251020625	0.0171212061704	0.330505354888	-0.0235378566776	0.511344034218	26.401	15.7	139.976
101	5.46539595473	3.3347410299	-1.00744971048	4.6829622288	-0.839944493054	1.59282974816	0.00597343460474	0.381128100865	-0.0612247022718	-0.501028476688	0.171961764803	0.546991197118	0.109298556307	-0.709017943621	-0.222143327673	0.407638114509	-0.0549134017851	-0.0893439711298	0.452820268862	0.0629369557529	0.410766308255	25.491	22.673	128.871
102	1.34740772071	1.73624967592	-2.39425830702	8.12983204319	-4.143452594	3.58628021663	-0.172328262675	1.44315623686	0.421032828216	1.40779422765	1.32105398926	1.55533913191	-0.315859116935	-0.712868530121	-0.821912594084	0.41012729339	0.016982110621	0.102569317588	0.662986752729	0.0564227298971	0.54713264799	17.554	19.406	143.951
103	9.02779233001	-1.46820417974	1.74685982534	3.9781831747	3.25878443692	4.45325129798	0.148813792649	0.00349389070376	-1.28482824732	-0.0212220422493	0.414956005965	0.623491989878	-0.157069105772	-1.71679410275	-0.341640402589	0.366153438368	0.00221092537353	0.326207815626	0.622558493849	0.0342337448563	0.73319405147	15.505	4.596	146.349
104	3.88855624476	4.06413023077	-0.144589660806	5.36318417403	-1.45690679996	5.48101228589	0.0471377796704	-1.54153809663	0.068121351421	-0.362513146313	-0.433181534161	0.485979403573	1.57831689079	0.138088417144	0.453378317217	0.454352757065	0.00308349907505	0.0448411147599	0.632712757672	0.0921761475846	0.68480104594	43.759	-8.167	137.724
105	7.18330904868	-4.95417885158	-1.24744729448	3.7211556054	-0.105018911343	8.28932418001	0.501546407734	0.0790753897823	-0.0919915186868	0.56258081371	-0.249940520445	0.216663303622	-0.103647310192	-0.0204817285471	-0.071096791202	0.270969903132	-0.104799080224	-0.0519738764827	0.459585660347	0.00478205845393	0.294361674516	47.304	2.318	129.379
106	5.62364832052	-2.62475642865	-0.281306057397	3.62328396534	-0.384820727614	4.68314155076	-0.137764326448	0.0906167499575	-0.184066715291	-0.324211041365	0.308811610481	-0.220353811993	0.25913649148	0.261752737794	-0.0755494071442	0.377720560116	-0.0495136572262	0.0251329711268	0.359451472902	-0.0316087706635	0.276169021751	52.117	0.518	123.874
107	8.32010082358	-0.169281539157	-0.963054515478	6.04235006138	0.621064991808	0.0473967058119	0.160915340908	0.151677089463	-0.212651246506	-0.321516573787	-0.0635547698131	0.326053113104	0.0360562176509	0.0919837998862	-0.206673410165	0.451894481904	-0.0249986474125	0.0258847349301	0.467674906023	3.00670777267E-6	0.247245692689	45.699	5.709	120.779
108	7.41726896477	5.23851420141	-0.179155989489	4.67412139915	-0.0901480455471	-0.550024275649	0.788049182289	-0.0133599680923	0.299261610156	0.633933275829	-0.485375596836	0.347141998832	0.12661215207	0.290675058216	-0.318669975076	0.539086029793	-0.103517712104	0.00206320814312	0.479873450664	0.0101068453886	0.300312729177	47.136	14.822	120.992
109	4.67172037604	5.49987484732	6.53196716838	8.07941548174	7.31540143558	7.62290527866	-0.259843355787	0.801368327334	0.238207317631	0.234615783524	0.221852660054	0.312650977115	0.413085564094	0.248237682875	-0.0866989892781	0.485507333371	-0.150645667925	-0.0134410938467	0.470089379335	0.0385481266252	0.321588096103	60.063	19.736	115.107
110	5.54521463857	0.435347913625	-1.19906208467	5.01110407343	-1.90567701211	3.5911269645	-0.196545423165	0.943724473362	0.311946156531	-1.14147909346	-0.24511226119	0.690616001089	-0.236341222477	0.308145241453	0.191532038071	0.689991427861	-0.0978331590095	0.0459301066046	0.442882754336	-0.0236035125947	0.356816058833	46.681	21.278	108.502
111	6.78543010415	3.54115910582	-0.503973039328	6.74593883682	-2.67342468602	1.29248388042	-0.781202542529	0.492087352115	0.520693173596	-0.751980232417	1.06441407158	1.58899740117	0.447662956039	0.45190711404	-0.0981293196224	0.55700969072	0.0237182627953	-0.0677176098484	0.390269329768	0.049953298648	0.475991780294	38.82	19.118	116.318
112	4.2644475044	1.13577804832	-2.08941744747	7.51258020465	-4.74072692347	6.10460494924	0.527457901176	-1.54223118772	-1.02632746457	-0.498458232512	-0.970722696767	0.485407732824	0.939231092476	-0.0229378499481	0.49824291232	0.436564850829	-0.153927552051	-0.158293448074	0.677577042501	0.00971675331838	0.718213772318	33.218	3.878	118.127
113	6.92200165839	2.67917458066	0.81283491436	5.60691871617	-5.08529268954	6.52985494255	-0.884145159535	-0.511932137028	-0.0840951268853	-1.25008140335	0.685097534813	2.21877404305	1.07467478528	0.589071368437	-0.128297568584	0.771799775807	-0.00850898897196	0.0712276896939	0.485641563684	0.0782823278808	0.644906483596	55.978	-8.842	136.981
114	4.30168185841	0.791966294595	1.34307888991	4.06531800265	-2.39095190054	4.84203813954	0.0934251159852	-0.360536815816	0.090196021217	0.605553397381	0.252699935179	0.144721351226	0.210334500623	0.0083338782428	-0.274172476658	0.553862878869	0.000429333420158	0.106106392716	0.309493828027	-0.0622485116158	0.336789135982	69.718	-3.963	135.041
115	4.44620139035	1.29953938495	0.359656577259	4.40022757313	-3.2911246384	5.35765389827	-0.0357030298111	0.476537702359	-0.19158805548	-0.388652121376	0.428610983341	-0.835499835556	0.800365272311	-0.0544534658399	-0.28653917383	0.422009878145	-0.0293734508677	0.0543315790758	0.523843288302	-0.00341392071562	0.231175609452	70.235	-3.73	127.579
116	2.43220071355	0.67263807221	1.37528839288	1.89325412274	-1.66221409826	4.58664494993	0.00876040062661	0.344545145324	-0.0633568774505	-0.191188012956	-0.0896697938701	-0.0732013677423	0.230568854161	0.42852283361	-0.0221234847928	0.43334702958	0.0432575310687	0.0935048282267	0.367387468164	-0.108124559061	0.388708054876	75.03	0.72	125.869
117	4.09956588515	2.53148759664	2.84093686668	1.78468425838	1.65596802949	1.47174476251	0.254432342909	-0.191117091674	-0.108154061919	0.332850613571	-0.316059406824	0.0895989448052	0.703975690748	-0.0902270122951	0.400639190074	0.35326019423	0.00291776944509	0.12277676702	0.462638201706	0.0274787044454	0.401253428904	75.573	17.292	129.733
118	2.06997012155	2.53150215516	4.3972616465	7.10049423792	6.4022304031	7.35131777295	0.0675351455017	0.736807234961	-0.0722803867593	0.0965692671847	0.0551529379032	-0.104935024156	0.334693201743	0.799014193948	-0.25992769823	0.440426826295	0.0417016580035	0.174711439343	0.596608640054	-0.0128877866979	0.476801999547	87.953	14.431	131.631
119	3.90957764341	-4.70977196829	1.84109051959	9.85292060626	3.63220993371	9.43718518358	-0.413085068263	0.124468980785	-0.282183348757	-0.287235344036	0.296129305256	-0.740755510188	-0.252373375871	0.23520137261	0.253161397212	0.536275731362	-0.0421058829837	0.205638918754	0.646299856904	0.0507092811089	0.488586504771	85.039	14.967	117.173
120	1.6907141058	2.11959138626	1.56107826172	4.21939975399	3.25052287675	2.23905045079	0.0539137294003	-0.182403677892	-0.555285117247	0.0325903975386	0.249477317431	-0.790157687997	0.095762977836	-0.205484131125	-0.269113663546	0.620768700357	0.0688704784986	0.0378607641158	0.416817576391	0.0787503021658	0.375348931315	73.75	14.338	115.911
121	3.43943927384	-1.02635742554	-4.71651634764	8.89929908531	0.772624784568	6.61999672764	0.241111960474	0.92609713448	0.20718250158	0.0070994908546	-0.00813238419526	0.0361981822743	0.928863458232	-0.987214843855	-0.317629305633	0.73124624789	-0.124168480667	0.1991779477	0.583049728687	-0.0347115410392	0.405904911743	66.312	0.727	113.064
122	9.70060497475	1.29933798089	4.69130787819	0.539014481101	0.784755825707	2.3691924241	0.455740914656	0.174376105113	-0.914319547761	0.906649282676	-0.362938204705	0.371550135609	-1.00283833719	-1.39985713727	0.0783982839348	0.782783112273	0.159680898174	0.175467164619	0.851233535648	-0.0622456915398	0.458400749657	66.578	-11.089	143.789
123	4.23979307007	1.87422863324	-0.946480418713	5.22065717557	-1.85633081354	5.35223107832	-0.219463670483	-0.263096809123	-0.443692200216	-0.16303780152	0.148757192017	-0.125583270414	0.289863174589	-0.0441664437747	0.0790997619027	0.369864549097	0.056310884848	0.0479421495567	0.396499896532	-0.00777879316193	0.411219311152	80.621	-6.518	153.097
124	8.16175505129	0.784149041462	3.44064704092	7.73322005657	2.87804437421	8.88262173617	0.690128567793	-0.0902169547155	-0.414778575973	0.00775278331783	-0.999075326896	0.35863847473	1.17207286885	-0.434085981593	0.583972776933	0.387108927108	0.0283507566872	0.0159264937297	0.334506980454	0.0449389942832	0.477293693852	85.974	3.108	148.007
125	1.2765473564	-0.932745593436	-1.18004167374	5.76051459486	6.47791984578	7.82319013237	-0.19930670207	-0.168353804603	-0.18976647962	-0.0437381420336	0.170495183419	0.10724770148	-0.0481312803667	0.328084089383	0.0126144760355	0.277344903297	0.00228757167193	0.0534230350491	0.489377464096	-0.00940720310258	0.387743374023	87.983	6.562	150.153
126	8.0647886371	-5.92311183333	-3.64150078521	6.10519172049	3.46166160803	3.47088928234	-0.219794155687	-0.417624093062	-0.203545145541	0.192127925729	0.446607889224	-0.0843509639898	0.425768856301	1.18174095228	-0.192029065888	0.352133464656	0.0364058079068	0.0820726005696	0.535554413081	0.0772323189618	0.462867142263	95.171	10.386	160.189
127	2.12529692039	-2.89036794584	-0.0462911772739	9.62503310286	6.38527462902	6.60535086476	-0.197608089653	0.933871345235	0.275502403843	0.391086036656	0.208614364893	-0.762780875992	0.331772388146	0.36084222572	-0.0828523156343	0.434088672457	0.00597398927205	0.143886558922	0.546835689655	0.0519471434751	0.47805312434	95.217	9.086	143.036
128	3.3428003217	2.76315140183	3.148927284	7.59332375681	-1.11012865532	5.75226870968	-0.756887234455	1.69135385011	-0.292425664421	0.194529563376	0.132394080801	0.00457755659634	0.585592876447	0.0345232588468	0.662463007508	0.571435911081	0.123544429132	0.197496649311	0.861372849409	-0.184966876546	0.644354683246	91.03	-5.144	136.67
129	5.30135450699	-3.00300128454	5.16368668847	2.86158360814	-1.9952636262	5.70707043469	1.03808255505	0.929763118048	-0.595859828337	-0.929519646503	-0.245326529763	0.0614977260447	1.88818746916	0.705315301927	-0.810853467606	0.65672420908	-0.0504231599434	0.0541330138089	0.518042714246	0.0495160437812	0.639088711655	67.697	-13.31	159.26
130	3.84581794377	0.926103108168	-0.750625349871	0.816347791673	0.466384167769	3.31905596062	-0.0892511740003	-0.119790819571	-0.145255544528	0.0335336168445	0.291078716668	0.0875157573651	0.428390754796	-0.00492186198603	-0.132157258781	0.518039821683	0.0390818942844	-0.0089254338089	0.324394308215	0.0419672104729	0.354439827907	68.304	-5.379	173.23
131	5.18010394297	2.38397654985	-1.16394509409	4.95714205774	-1.49828184248	4.51797017899	-0.0253204613584	-0.416394666076	-0.327840600615	-0.0209316382853	-0.199791031547	0.213804915948	0.220738269757	0.24615554949	-0.0765393791917	0.353473303398	0.0333924191086	-0.00914960764695	0.277489477865	0.00542754368796	0.392832528283	76.26	-3.42	174.742
132	1.71960235562	-0.266166042343	-1.40016504741	0.856818692915	0.850438504972	2.4171949989	0.221385217761	-0.14614643977	-0.0640274890806	-0.41218577158	0.0104189244033	-0.201353113119	-0.019534219139	0.140807366537	-0.190600217971	0.395633567446	0.0968441357824	0.00259943115017	0.35958946364	-0.00206195559483	0.330339407087	77.568	5.733	176.162
133	6.64313408057	-6.67063642623	-0.553939283703	7.23943238166	-0.414969873535	4.41994696028	-0.130720896184	-0.433730042344	-0.245579660864	-0.0301106377066	0.225368075553	0.073393073288	0.841009386491	-0.186464756114	-0.230525081843	0.391615981261	-0.0939462167591	-0.0554336116189	0.430674388159	-0.00835020901039	0.350569176234	70.2	11.711	187.795
134	2.28986731617	1.81811272275	-0.96708299064	1.37330449169	-0.40552065668	2.12693733995	0.214528363233	-0.0343871421705	-0.220194534584	0.0260170401453	0.218871444913	-0.270544335603	-0.19464209737	0.00908705220793	-0.389339410043	0.330743115933	0.0821300228602	-0.0205769510119	0.503817907797	0.0131714443981	0.510487535857	86.663	7.742	181.588
135	6.11181329671	5.38425453088	3.83165129498	8.23984485368	8.02193111871	8.81663963381	0.0230417633944	-0.13810783011	-0.826854812893	1.43226816376	0.4783912386	-1.22294613234	3.0254498288	1.36352502863	-0.250227614196	0.684958835182	0.110235490889	-0.0508488770446	0.426993424903	0.0988759336481	0.813539412424	87.845	-9.036	170.825
136	4.093081523	0.943577943099	-3.88695802544	8.54857612263	1.54967980532	4.44512849218	1.49489426628	1.44239344983	-1.17213691308	-0.61424930661	-1.54372588874	-1.01283150478	-0.951503597464	0.306619767008	0.289267161447	0.895220230078	0.275578973203	-0.0455072271179	0.696435618507	-0.0505613095476	0.541804110816	57.157	-10.702	165.564
137	6.42953170587	1.30681078378	1.07211624631	2.28082487383	2.05538902686	3.62429425924	0.130889795924	0.116181827108	-0.39194431066	0.199942401898	-0.190451916537	-0.166823268508	0.468171985886	-0.443069394954	-0.0165401765486	0.568302070345	-0.0501104126065	0.0858734365149	0.475975887857	0.130630894579	0.352261432963	47.951	-4.867	174.427
138	5.27532573565	0.545367981367	1.31286431653	3.29700388641	0.675924133062	3.93529046012	0.0219741161687	-0.225933332107	0.059913902503	0.110832861472	-0.0024654946779	0.168160933619	0.2308102759	-0.74536179075	0.0979841942332	0.43068450208	-0.0454086997243	0.0979032894147	0.557201224562	0.0617178420185	0.402283529245	46.167	0.314	181.45
139	4.33104609257	-1.15283665044	-1.6419552815	1.66762080035	1.11621643157	0.891158703057	0.33103663496	-0.303996095081	-0.012438646822	-0.282470584016	-0.376478886147	-0.343864406541	0.292458391764	-0.194044850264	0.0366806564512	0.450415542401	-0.0460661110332	0.0324147175428	0.471596959283	0.0218455534251	0.24172222978	50.698	8.589	184.172
140	1.77759106831	-2.01961081088	2.42642760288	7.32671995051	-5.18392899916	4.1462047073	-0.324334230574	-0.689355332666	-0.384885203392	0.693109560733	0.424393138524	0.748496888043	-0.329374278299	-0.713070659722	-0.126961508397	0.540514472111	0.0816472004663	0.155704202447	0.745089374459	0.0277084926589	0.31255829997	37.705	16.277	185.266
141	4.050087746	-1.82348346806	0.355180242898	7.15882657521	-0.347637488289	0.0576827875003	-0.434283698669	-1.39633407773	0.281604497006	1.28640358764	0.929564462511	0.322458010511	-0.0879996645805	-0.173573151719	-0.495511957112	0.598892544216	0.0338204705125	0.0394244098318	0.709454747964	0.00689219545629	0.352710351779	52.383	11.077	194.611
142	3.27178371744	-1.54965040807	-4.26038484897	9.72284337301	4.86357588062	6.10608203709	-0.954352561044	-0.75933546176	-0.321017327285	1.37220947085	0.842623279333	-0.443337714178	0.625696284838	0.928885566992	0.0227598840331	0.683361581662	0.0817725639064	-0.087026663371	0.631041799396	0.178503537783	0.361354686164	59.998	-5.553	190.44
143	5.10104892748	-4.97734532173	1.05306884764	8.25209108572	1.90373473208	2.6752940551	-0.291059834683	-1.59368740247	0.051917688612	-0.886442474662	-0.169665931715	-0.909314330885	1.15060539277	2.16401688539	0.502262748458	0.631617544231	-0.0205628456812	0.0633057516058	1.04090331984	0.362884387995	0.615516163846	44.269	-7.831	162.686
144	4.27335663242	-0.945275021163	-1.35855763298	0.260304406296	-0.395583848638	6.1856185217	-0.118727900206	0.388631359877	-0.355213889203	-0.36203205786	-0.175966528189	-1.47003164441	0.137599729177	-0.181833936225	0.206095261027	0.404076760374	0.0743667065355	0.0795630409124	0.52213036509	0.0820497858561	0.492365228058	35.463	-0.697	162.85
145	5.75605305302	-2.22535148904	1.24302231897	4.11924062174	2.53752495553	3.24274305591	0.445755853848	0.56597823887	-0.104036058522	-0.660543475138	-0.232740430311	-1.22208537559	0.0455386786691	0.82974156874	-0.0933539784537	0.511607241256	-0.0476722053346	0.0841483336946	0.445389185624	0.0371170609625	0.51175805213	31.737	-1.937	155.166
146	4.58199838717	-1.31278362678	0.171288569424	2.73306362121	2.0176072144	1.96016141494	-0.0552246436254	-0.315912881162	-0.400257489156	-0.184015087504	-0.0168936060971	0.0207365248584	0.165810310518	-0.14325891759	0.022449077823	0.358543128715	0.0165653368897	0.0427006418179	0.390136846001	0.0728581045609	0.365639905354	27.159	1.544	161.595
147	2.13420913887	-1.89566642015	1.22503337538	3.30369920992	-0.300429877166	2.82651119469	0.113410335175	-0.313978854593	-0.282870744483	0.152539609531	-0.406933297634	0.79821917065	-0.116393559186	0.0170583824651	-0.3014801353	0.522673852674	-0.120572063007	0.0276988603796	0.492446884755	0.0984760672401	0.486795656585	24.691	-3.11	165.32
148	5.91428207364	1.50121619702	0.892310620034	2.87505812041	0.723037667325	3.2070774685	0.143009890451	0.201453365971	-0.414917696158	0.712451215329	0.040964081497	-0.0174242276937	-0.210185446053	0.136935022029	0.139488361141	0.534813154802	-0.021354037123	0.110220514908	0.489694339266	0.0910727750315	0.54052429813	29.656	8.893	168.733
149	2.08599934999	-1.70312423936	1.20539574617	3.00265692624	-1.9708155527	1.52340521259	-0.23175850184	-0.281638344435	-0.00748838945969	0.214439583481	0.0105422466992	-0.221804987894	-0.256576063156	0.00134500606873	0.189235101532	0.38936729825	-0.0664212351887	0.0222757580761	0.586734312254	0.0484797303043	0.364142136111	27.989	13.002	168.037
150	3.39110841539	3.6730732366	-3.21869323197	9.34301407124	-7.63096260144	6.58374556276	-0.183775972292	-0.0140580347982	0.14227414713	-0.724815425981	0.669283963397	0.622799282062	0.492749871051	-1.02311045704	-0.345814507443	0.351703059577	0.00411499281248	0.0665091433067	0.515515671803	0.0329806207664	0.44076023883	19.855	21.033	158.264
151	2.05108477002	7.41634627998	3.90878750267	5.25953556765	2.83026512511	2.73921096514	0.437414210027	-0.90189253373	0.493153476463	0.494927491586	-0.991420246747	1.0358694702	-0.735538370533	-0.263458323173	0.520759929929	0.50524774904	0.0320974644313	0.150092530529	0.810615997816	0.197117094929	0.707568775313	15.915	18.836	172.671
152	0.225493622216	-1.21521432798	1.557553532	5.07764431354	-6.83071260245	8.77665090048	-0.186210457404	-0.735529688177	0.0978429106488	0.928537275342	0.785207444958	1.1065259643	-0.484198195534	-0.795653891486	-0.536590268392	0.411181915861	0.0402638224358	0.0906053237521	0.888595538247	0.0015213009193	0.465744314036	25.176	15.259	177.856
153	3.20646364242	1.95970661817	-1.41181504797	1.86265641315	1.0784383072	5.58684161549	0.149360713274	-1.31478702022	-1.22402700591	0.677850886929	0.847314728138	1.37128365376	0.739877191134	-1.09317309692	-0.731220483891	0.547525359017	-0.12110402008	0.171943885006	0.491021827075	0.191153171895	0.582959347946	27.077	-1.3	179.635
154	8.42672911264	-4.74227387889	2.28773492333	5.57216694747	-2.53684041484	5.07810203572	-0.0827167119012	-0.648725494467	0.933643732138	0.508871552473	-0.277834711253	-0.41801139599	-0.271381376355	0.411807279396	0.404503627716	0.446480386275	-0.130756897862	0.0383737951313	0.441695662528	-0.0504538443224	0.360695294077	61.196	62.07	138.218
155	5.25081233136	-0.295872115019	-1.77543919815	2.9911831158	3.18564520076	4.30853498888	0.0441327978758	-0.0589974754393	0.178054090584	-0.123831710821	0.0554445468996	0.412267071382	-0.0811857827889	0.0115294955152	-0.114103501438	0.396672352805	-0.023739988924	0.0303346749621	0.279192497166	0.0665611071449	0.415386908895	51.997	59.625	129.037
156	4.65785101153	1.96511940426	-1.66903822928	0.544303418165	-0.313267410524	1.44815477578	-0.365541303811	0.543516684606	0.169512173748	-0.444264900856	0.298514301782	0.0383765014788	0.193062775972	-0.328683935637	0.142695609706	0.504655205293	-0.103357689693	-0.00334064889984	0.451683571901	0.0841192601536	0.402995425179	46.141	43.578	120.869
157	3.09577646813	1.43078625339	3.34824568229	2.42077293177	0.87778355888	8.42792528739	-1.1026640435	0.362500410513	1.7273930286	-1.29982113944	0.259034689302	0.880466188414	-1.45808468949	0.735508238686	0.765745003001	0.751148735785	-0.0937946720426	0.0149651423641	0.366809581614	0.0426974549008	0.790854439345	64.309	60.825	117.613
158	7.02659744757	-1.07054891616	1.25541843765	2.58550418804	-0.548388606898	5.78460739087	-0.074495104967	-0.941550570857	0.419397935494	0.119694008245	0.00107884264159	-0.257867587461	-0.24762580571	-0.102157512138	0.156032644453	0.371582522766	-0.0179597958424	0.00643995237215	0.442424539866	-0.0462567473015	0.426609232235	73.588	59.536	138.604
159	6.19940700528	-1.63976507232	1.18806985768	2.88647242902	-1.23318554353	3.3606640729	-0.00861959063994	-0.0507236271862	0.4846671535	0.0107280505948	0.026547807272	-0.00490072567633	-0.128921256195	0.143270319687	-0.0746712803727	0.346110340841	-0.057930282969	0.0527415776097	0.286137942297	-0.0556355336231	0.347101564891	77.982	54.79	130.394
160	3.29029132499	2.20848726626	3.73139726126	2.38206815377	2.42682170597	3.5107431259	0.343527152472	-0.37584600609	0.213819343588	0.179772442748	-0.205782093528	-0.0167433764248	0.223308939611	0.113122508348	-0.110583152445	0.329846987655	-0.0241393421089	0.154108831494	0.368400895311	-0.0399425955334	0.359294552167	79.789	43.74	129.056
161	8.31508235708	5.0452223316	-0.221742420355	5.16263858108	-0.375734538653	0.823174539915	0.382858860556	0.451450772338	0.517797340173	0.126441208373	-0.262189111344	0.118682081954	-0.0052370965303	0.0901994473779	-0.106134653393	0.437485346328	-0.0675018061718	0.0910015237667	0.453597676058	-0.0163075886141	0.383379619238	69.754	40.027	118.384
162	5.85864260392	6.32771989418	-5.88411255316	7.7824114394	-5.11742258177	7.54899727037	-1.42207339288	1.63676938025	-1.85883911678	-1.29211957155	0.781030057408	0.0446741402326	0.462215089221	-0.659772567536	0.487953993897	0.417273876209	-0.120155916379	0.121965224964	0.713148745163	-0.12129318488	0.638595420837	84.706	39.237	116.839
163	6.59650099771	7.09634486613	6.05545569869	7.50370398539	6.71185591199	5.89437404331	-0.0535627581606	0.745910466233	-0.512164159108	0.200712904484	0.635248936242	-0.720735699025	0.249439299987	0.700881341038	-0.702080205426	0.303131537105	0.0975437828653	0.0300176788444	0.485853241848	0.113390323512	0.590548907486	89.179	39.756	127.118
164	7.48239985716	2.24610931593	1.89297543585	4.68006252821	2.32353714647	9.39516430457	0.380490187965	-0.910967019656	-0.748361347768	-0.10068769736	-0.0249181107625	-0.815815669581	-0.143907286028	-1.00835573487	-0.0640522248941	0.405995635098	-0.135624443578	0.225201015949	0.55176319979	-0.101928056598	0.708839818661	93.23	53.71	131.278
165	1.94074487037	3.71868815852	-3.30427530062	8.2831865675	-4.44440824892	7.61733893568	0.589120088103	-0.387061071653	0.157056021433	-0.00745769473964	-0.15726741882	0.350105775408	0.0419382185877	-0.50946272746	-0.674331718672	0.611025549533	0.14387244821	-0.106992509361	0.627763590088	0.0605728045922	0.521015127506	78.313	62.056	161.963
166	4.69496167817	-2.26181515275	1.08997396375	5.16500949003	-1.28132994885	5.30510557441	-0.220116326365	0.523951008189	0.227621597252	-0.00291442125623	0.159362872628	-0.135168422921	-0.115679728388	-0.0531571823508	0.0667971366226	0.29116024621	-0.0832235211312	-0.0175815134907	0.390800610503	-0.0111964255048	0.371651501743	89.298	52.481	152.03
167	1.46105202445	0.3005274806	-0.46767662839	-0.0641213273554	0.403800203074	3.77683787462	-0.204855276989	-0.290958363704	0.2624404195	0.200979930201	-0.326326808672	0.22432413419	0.00440386213736	0.257168224476	0.296572328338	0.271246841754	0.0741742802748	-0.0599831832836	0.478445759912	-0.0400830847578	0.555724100101	92.811	39.747	153.741
168	7.58580035211	3.29052371578	5.26470977198	1.78440939993	3.37814671296	4.08039164308	-0.0927139525826	0.566332787052	-0.149074378957	-0.198591916865	0.167062912314	-0.106666700754	-0.0594542412459	0.954417939508	-0.0226851430055	0.383588563357	-0.0876100335818	0.0565572912694	0.51816322845	-0.00121251184922	0.496747539069	97.5	34.275	142.716
169	4.06014958597	5.00789358369	2.02641082483	6.74986328311	4.44788324617	6.77729381287	-0.226756925256	-0.481365609938	0.222232115372	-0.471802718692	-0.0324960018378	0.144691052063	-0.565691541811	0.32425482636	0.267798674477	0.368838794303	0.00847645727694	-0.111266490909	0.506384620001	0.042608735478	0.487408909641	100.147	40.571	161.75
170	5.64312456802	2.46930576147	-5.10515393124	3.93921853243	0.930239538234	8.32047434315	-0.196127068149	0.12168680338	0.537350250398	-0.18286968837	-0.203243347123	0.873546488391	-1.64787620265	-0.0332151364155	0.267096253206	0.759624521292	0.0482731811629	-0.168725965824	0.451524732652	0.131455755542	0.516726248636	68.753	62.315	172.131
171	6.62785854346	-1.50604478464	-0.668391757201	4.49816251195	-1.86111403379	5.01663443169	-0.179448681631	0.0945300426762	0.281763622673	-0.187048871836	-0.0106164829889	-0.180579305287	-0.303228666133	0.166117213072	0.0863924930181	0.376160392987	0.00108520682469	-0.0435915014564	0.338019489894	-0.0210511229428	0.254507744901	82.078	52.633	172.844
172	1.54842543355	-2.40512333578	-2.07703855036	3.07025611441	2.32574926722	2.3862822051	-0.149284387928	0.210367484441	-0.106049964233	0.0421167588997	-0.0943025200803	0.125191086437	-0.0490528850852	0.164261433357	0.290247809604	0.411867363976	0.0192888558896	-0.0717921145711	0.367577290545	0.000291768899623	0.331544125122	81.626	43.03	179.744
173	0.291596798147	1.13659014961	1.63091471242	4.46651967073	4.25365639092	6.32580242737	-0.153568090621	-0.140091250947	0.324527869213	-0.0487975293348	0.342667862905	-0.204166854629	-0.17495726642	0.625465425664	-0.207951010968	0.343402557389	0.0339289715469	-0.0858203342808	0.531287981441	-0.0296274774554	0.404044193004	92.163	32.027	176.733
174	1.89125757087	1.68019410011	-1.33169745594	6.21164260595	3.64361441652	6.40551596673	-0.518619587084	-0.0217774483768	0.199283665828	0.85434672585	0.648119321442	0.283134373996	-0.201033474371	0.268799473075	-0.108197288572	0.471012499776	0.0570112689717	-0.0722477307792	0.452310817694	0.0410493388383	0.389441807843	79.335	41.85	190.245
175	6.11175826257	-5.18011647977	5.31081522221	6.87701336653	-6.46523377354	9.31269411146	-0.22670090302	-0.216981636851	1.27635374141	-1.36654019684	-0.650181843633	0.385174605733	-0.601272863912	0.121784676226	0.95143865367	0.664787458731	0.211735337303	-0.113845885895	0.876087507518	-0.219241394279	0.617316445167	54.517	63.64	169.938
176	8.99598750438	0.797591407801	-0.752801713103	2.10382788678	3.4933368906	8.57573652747	0.403396677905	-0.101182578599	0.208191066135	-0.852865866842	-0.247517559804	0.37123496917	-0.0693792496072	0.0193561957052	-0.014524702129	0.466310019209	0.140662957336	0.00830977858803	0.416320161162	0.0252669882881	0.455137509779	56.841	55.497	178.195
177	5.98004085649	1.93573790911	-0.222509906435	8.53323994483	-1.10487382795	3.47030189235	-0.0615143977806	0.284304247828	0.151419819734	-0.847077840188	0.546958693522	-1.10295332389	0.129131578996	0.282065712581	-0.132991798638	0.514117976522	0.101474449401	-0.0484290730149	0.479747198666	-0.0412755135532	0.354602395067	65.41	56.871	179.227
178	3.8336182109	-0.0156154723352	-1.60643464457	5.59670298196	-1.02179654704	2.44113847461	0.134820596361	-0.364111358542	0.435756162331	0.601020263566	0.13874353857	-0.49375649434	0.0628275755863	-0.195532303523	-0.242872619417	0.577625212289	0.0786733128064	-0.0660109465312	0.466765472185	-0.0730136222863	0.339388211583	60.209	54.391	186.441
179	3.2230085143	-1.71686980012	0.390555758863	2.43440081554	0.590049593085	3.31917420457	-0.332043338013	-0.024815594163	0.391289858324	-0.5005679048	0.207576295438	-0.571227930439	-1.09518789234	0.608791721045	-0.0795856472031	0.626258615899	0.0500603785508	0.0153479395183	0.500944051972	-0.117469806332	0.514428476339	53.214	46.044	185.6
180	2.24018861122	-2.04889951744	0.272773468871	2.86571841835	-0.654469743284	1.11315788351	-0.274034846816	-0.284657489112	-0.0949760716418	0.259449965575	0.319001750684	0.183442842941	-0.100114418743	0.23176260647	-0.150021327964	0.49849619635	0.0523570474592	-0.0189741814519	0.434543668271	-0.0563126628318	0.267597716464	54.381	41.888	186.98
181	7.99010995837	-5.9719821307	-7.30763247038	4.88382336445	6.47583638778	8.32531380906	-0.206816360324	-0.929016566562	-0.114991721205	-0.142727742974	0.34107797442	0.0379401079803	-0.108602479935	0.511975930803	-0.0979608989141	0.447702076452	0.0277898579764	0.0343369271928	0.544444529812	-0.00383402759356	0.304919295467	66.165	33.852	191.565
182	8.30308519119	-0.701906903698	-0.493733795228	7.2865647873	6.91696414121	8.69272278038	-0.224671806225	-0.317685490804	-1.06588723095	1.10519824212	-0.085801177667	0.135113455827	1.41673128607	-0.812194431659	0.442960930792	0.714979853367	0.0904721445022	0.0892727919223	0.878412482529	-0.0120882010136	0.394666973261	53.827	35.973	199.621
183	5.78181112652	-6.74514388337	-0.907172041189	8.05729178536	1.23765364096	0.406608586676	-0.649208374938	-1.02690097114	-0.571444183593	1.18968917532	0.577959962378	1.01267917992	0.00286044200549	0.324253244199	0.0150982806863	0.490070850808	0.0400677354838	0.213736810325	0.743138597958	-0.122806092534	0.573852933015	45.91	39.788	192.705
184	4.25664069571	-4.61111956025	6.22783634988	4.8484234538	-6.5843266964	8.77670182545	-0.703941668852	0.235622900746	-0.247835645402	0.931706415374	0.623558688137	0.550425720458	-1.60636075594	-0.884389060761	0.383091533672	0.608839230111	0.214981654329	0.0393980387161	0.768628629151	-0.12386730112	0.632861737262	43.833	55.998	191.631
185	4.24058504573	-0.636208793607	1.47659863545	7.89713644438	-6.33847314729	9.38982959082	-0.148819550566	0.253232920475	0.394348463773	-0.10209727416	-0.212869077038	-0.492845962714	-0.327189890059	0.279207508959	0.379162009338	0.342126167015	0.0985323033588	0.0354317554596	0.41359576264	-0.000145678491394	0.568961559995	44.469	61.576	162.647
186	6.91211335408	1.0516809429	1.54765228344	1.77875858825	0.513074851348	6.28401202424	-0.0925866697286	-0.0381482748154	0.493237792784	0.275129295009	-0.47318766803	-0.242256639918	-0.818228823399	-0.176180452586	0.592576111297	0.561099753839	0.138507611547	-0.0527980080422	0.463665634422	0.0496546080951	0.366753883316	46.483	59.791	173.145
187	4.64698303214	1.55589847402	2.09154139542	1.60513786134	-1.046960102	3.78013445203	-0.363233669446	-0.479273902278	0.629251170648	0.34193167353	0.152728334276	0.304856894924	-0.468363483022	-0.300117197059	0.235750357729	0.489186376711	0.144976344876	-0.014312023469	0.367049285848	-0.0855205650133	0.426741711493	36.379	56.5	172.563
188	0.202349228239	0.27147875049	0.102143263019	0.975442420238	-1.38661601678	4.26011415107	-0.0232189464995	-0.507789555512	0.268082055571	-0.0867049748887	0.185201336901	0.0938901828951	-0.215401425613	-0.396594881086	-0.208107218355	0.352509344538	0.114305959766	0.102724050573	0.600553884306	-0.0433378643005	0.488126768723	31.918	46.313	170.589
189	5.64092478199	-7.13111418392	2.25138900331	7.99789669615	-1.53069411821	1.68528613172	-0.0179447335649	-1.06147363779	0.723326350775	-0.358108019688	0.226248044034	-0.885874619673	-0.263881814534	-0.555232387778	-0.217633794596	0.413429370793	0.0487864033266	0.197172032216	0.723653096375	-0.000281698031398	0.521976270159	34.923	38.7	183.157
190	1.32955912909	-1.30111506997	2.56996899339	7.37418233423	-4.74346003185	5.3653275653	0.165329360373	-0.357184876726	-0.0626036214739	1.14654231526	0.308632010117	1.15240989018	-0.366660665579	-0.354314581998	-0.498869625515	0.471084068951	0.106979123787	0.11541719593	0.656366630748	-0.0305831000669	0.516142216415	21.597	43.84	172.35
191	8.96377345171	0.52549507359	-4.40337668936	7.09306369531	4.1688090188	4.94192226592	0.621931410377	0.681750064565	1.51673477595	-0.0629258160578	0.0890273068024	0.766588868484	0.624168688619	-0.218482860197	-0.267283216445	0.533013264696	0.263725665318	0.305109584849	0.706092355107	0.119468644971	0.843906346168	23.09	59.574	164.908
192	2.2018341198	-2.68529946033	1.35847283763	8.36135818161	2.40339790516	5.41856120646	0.529602631399	1.03181206853	1.73179556209	-1.68050657236	-0.91068589153	-0.605099788447	-0.510919917258	0.475303356285	0.301770004825	0.66784613995	-0.0780186263576	0.150564625127	0.490595613366	0.12772912229	0.650408264433	52.71	66.602	146.161
193	5.01414716967	-0.0566143515939	0.0592839080529	2.03008003369	-1.40080986448	8.92022054279	-0.225813800414	-0.173913567024	0.250287885495	0.426763970062	0.181968322429	-0.445773474167	-0.759887167643	0.196974867075	0.112745601214	0.392178157233	0.0598714999724	-0.0103044255084	0.281285169816	0.00484841233064	0.592502564552	40.711	61.448	151.127
194	3.58244961818	-0.114238560807	1.00968585701	2.07951042034	-1.92634623734	6.16198397572	-0.233704846793	-0.130221525705	0.0692976535799	0.286900064934	0.259957640607	0.338571850465	-0.579729700181	-0.538808473976	-0.105860790985	0.404847271105	0.0672916753818	0.0582629967395	0.389465303535	-0.001056742291	0.554951392124	33.721	60.085	148.717
195	5.19077407631	0.450222015541	-1.27289603933	4.34771388043	0.306568750775	2.81193179734	-0.307870881897	-0.345480406387	0.743021356698	-0.0133182664141	0.377371489828	-0.222541552135	-0.32556479449	-0.209621429923	-0.12383585049	0.471362899126	0.107579966214	0.00353920862589	0.258065551387	-0.0176783562098	0.468844868513	32.85	57.974	143.206
196	0.649975924948	2.3647938495	-1.76182282302	6.95109884978	-5.17172523903	5.43235790816	-0.300353094719	-0.183952174753	-0.157705762993	-0.26791284217	-0.192431165148	-0.560376585479	-0.0249242951842	-0.12948516946	0.577134672979	0.28608429202	0.048697890793	-0.0435833909988	0.434464122278	0.0832011893612	0.503068037853	30.924	48.954	142.395
197	0.753050477802	-2.2769588846	2.21880301512	9.2432350226	-8.09718902447	7.97490734649	-0.359437561677	-0.202834085462	0.000376596262487	0.308414015407	0.380608259449	-0.0607723039629	-0.417005530779	-0.762334049451	-0.214509265571	0.278488210989	0.0372486993142	0.0018419750816	0.498322298918	0.0207945887537	0.487316564825	22.297	43.123	153.178
198	2.78210379172	1.81080636944	-0.111689175233	3.61374985374	-4.44287363666	8.07152606435	-0.466599340885	-0.748641907903	-0.158340123579	-1.2596928898	0.229334969817	0.531390570108	-0.150958066891	-1.09261531432	0.441053438798	0.652109778388	0.091060514461	-0.12545051769	0.40560231364	0.0360790856573	0.534552226185	16.629	46.465	139.414
199	2.55714522747	2.5114393174	-1.34355021969	4.04123940768	-0.0956243569477	2.87076250386	-0.352642085378	-0.279846310514	0.406264201217	-0.598450166814	1.26447863102	2.01109996244	0.231919885127	-0.313490367821	-0.814447085353	0.470319057519	0.0825445275359	0.0010247577406	0.496640653963	0.0552226182009	0.53872456444	26.461	47.304	133.538
200	5.62273995472	4.00536516756	-3.83195659217	3.35678772683	-2.03178762506	4.13774375219	0.430499128329	0.964666040007	2.72359273135	0.852927273592	0.979838213635	0.574351119518	-1.41662184688	-0.703948680009	-1.30926646199	0.908119906653	0.019870304667	0.08298223656	0.48981790305	0.180867112376	0.739622225416	32.29	63.112	130.685

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth asym-ID	Auth seq-ID
1	X-RAY DIFFRACTION	1	( CHAIN A AND RESID 2:24 )	A	2 - 24
2	X-RAY DIFFRACTION	2	( CHAIN A AND RESID 25:36 )	A	25 - 36
3	X-RAY DIFFRACTION	3	( CHAIN A AND RESID 37:53 )	A	37 - 53
4	X-RAY DIFFRACTION	4	( CHAIN A AND RESID 54:82 )	A	54 - 82
5	X-RAY DIFFRACTION	5	( CHAIN A AND RESID 83:114 )	A	83 - 114
6	X-RAY DIFFRACTION	6	( CHAIN A AND RESID 115:131 )	A	115 - 131
7	X-RAY DIFFRACTION	7	( CHAIN A AND RESID 132:157 )	A	132 - 157
8	X-RAY DIFFRACTION	8	( CHAIN A AND RESID 158:168 )	A	158 - 168
9	X-RAY DIFFRACTION	9	( CHAIN A AND RESID 169:182 )	A	169 - 182
10	X-RAY DIFFRACTION	10	( CHAIN A AND RESID 183:193 )	A	183 - 193
11	X-RAY DIFFRACTION	11	( CHAIN B AND RESID 3:69 )	B	3 - 69
12	X-RAY DIFFRACTION	12	( CHAIN B AND RESID 70:131 )	B	70 - 131
13	X-RAY DIFFRACTION	13	( CHAIN B AND RESID 132:192 )	B	132 - 192
14	X-RAY DIFFRACTION	14	( CHAIN C AND RESID 3:69 )	C	3 - 69
15	X-RAY DIFFRACTION	15	( CHAIN C AND RESID 70:131 )	C	70 - 131
16	X-RAY DIFFRACTION	16	( CHAIN C AND RESID 132:191 )	C	132 - 191
17	X-RAY DIFFRACTION	17	( CHAIN D AND RESID 3:25 )	D	3 - 25
18	X-RAY DIFFRACTION	18	( CHAIN D AND RESID 26:53 )	D	26 - 53
19	X-RAY DIFFRACTION	19	( CHAIN D AND RESID 54:69 )	D	54 - 69
20	X-RAY DIFFRACTION	20	( CHAIN D AND RESID 70:114 )	D	70 - 114
21	X-RAY DIFFRACTION	21	( CHAIN D AND RESID 115:131 )	D	115 - 131
22	X-RAY DIFFRACTION	22	( CHAIN D AND RESID 132:157 )	D	132 - 157
23	X-RAY DIFFRACTION	23	( CHAIN D AND RESID 158:182 )	D	158 - 182
24	X-RAY DIFFRACTION	24	( CHAIN D AND RESID 183:192 )	D	183 - 192
25	X-RAY DIFFRACTION	25	( CHAIN E AND RESID 2:25 )	E	2 - 25
26	X-RAY DIFFRACTION	26	( CHAIN E AND RESID 26:131 )	E	26 - 131
27	X-RAY DIFFRACTION	27	( CHAIN E AND RESID 132:168 )	E	132 - 168
28	X-RAY DIFFRACTION	28	( CHAIN E AND RESID 169:193 )	E	169 - 193
29	X-RAY DIFFRACTION	29	( CHAIN F AND RESID 3:25 )	F	3 - 25
30	X-RAY DIFFRACTION	30	( CHAIN F AND RESID 26:91 )	F	26 - 91
31	X-RAY DIFFRACTION	31	( CHAIN F AND RESID 92:104 )	F	92 - 104
32	X-RAY DIFFRACTION	32	( CHAIN F AND RESID 105:131 )	F	105 - 131
33	X-RAY DIFFRACTION	33	( CHAIN F AND RESID 132:157 )	F	132 - 157
34	X-RAY DIFFRACTION	34	( CHAIN F AND RESID 158:168 )	F	158 - 168
35	X-RAY DIFFRACTION	35	( CHAIN F AND RESID 169:182 )	F	169 - 182
36	X-RAY DIFFRACTION	36	( CHAIN F AND RESID 183:193 )	F	183 - 193
37	X-RAY DIFFRACTION	37	( CHAIN G AND RESID 3:24 )	G	3 - 24
38	X-RAY DIFFRACTION	38	( CHAIN G AND RESID 25:91 )	G	25 - 91
39	X-RAY DIFFRACTION	39	( CHAIN G AND RESID 92:114 )	G	92 - 114
40	X-RAY DIFFRACTION	40	( CHAIN G AND RESID 115:131 )	G	115 - 131
41	X-RAY DIFFRACTION	41	( CHAIN G AND RESID 132:157 )	G	132 - 157
42	X-RAY DIFFRACTION	42	( CHAIN G AND RESID 158:168 )	G	158 - 168
43	X-RAY DIFFRACTION	43	( CHAIN G AND RESID 169:182 )	G	169 - 182
44	X-RAY DIFFRACTION	44	( CHAIN G AND RESID 183:192 )	G	183 - 192
45	X-RAY DIFFRACTION	45	( CHAIN H AND RESID 17:26 )	H	17 - 26
46	X-RAY DIFFRACTION	46	( CHAIN H AND RESID 27:69 )	H	27 - 69
47	X-RAY DIFFRACTION	47	( CHAIN H AND RESID 70:91 )	H	70 - 91
48	X-RAY DIFFRACTION	48	( CHAIN H AND RESID 92:104 )	H	92 - 104
49	X-RAY DIFFRACTION	49	( CHAIN H AND RESID 105:131 )	H	105 - 131
50	X-RAY DIFFRACTION	50	( CHAIN H AND RESID 132:168 )	H	132 - 168
51	X-RAY DIFFRACTION	51	( CHAIN H AND RESID 169:182 )	H	169 - 182
52	X-RAY DIFFRACTION	52	( CHAIN H AND RESID 183:193 )	H	183 - 193
53	X-RAY DIFFRACTION	53	( CHAIN I AND RESID 2:26 )	I	2 - 26
54	X-RAY DIFFRACTION	54	( CHAIN I AND RESID 27:114 )	I	27 - 114
55	X-RAY DIFFRACTION	55	( CHAIN I AND RESID 115:131 )	I	115 - 131
56	X-RAY DIFFRACTION	56	( CHAIN I AND RESID 132:168 )	I	132 - 168
57	X-RAY DIFFRACTION	57	( CHAIN I AND RESID 169:182 )	I	169 - 182
58	X-RAY DIFFRACTION	58	( CHAIN I AND RESID 183:193 )	I	183 - 193
59	X-RAY DIFFRACTION	59	( CHAIN J AND RESID 3:24 )	J	3 - 24
60	X-RAY DIFFRACTION	60	( CHAIN J AND RESID 25:53 )	J	25 - 53
61	X-RAY DIFFRACTION	61	( CHAIN J AND RESID 54:104 )	J	54 - 104
62	X-RAY DIFFRACTION	62	( CHAIN J AND RESID 105:131 )	J	105 - 131
63	X-RAY DIFFRACTION	63	( CHAIN J AND RESID 132:157 )	J	132 - 157
64	X-RAY DIFFRACTION	64	( CHAIN J AND RESID 158:168 )	J	158 - 168
65	X-RAY DIFFRACTION	65	( CHAIN J AND RESID 169:182 )	J	169 - 182
66	X-RAY DIFFRACTION	66	( CHAIN J AND RESID 183:193 )	J	183 - 193
67	X-RAY DIFFRACTION	67	( CHAIN K AND RESID 3:25 )	K	3 - 25
68	X-RAY DIFFRACTION	68	( CHAIN K AND RESID 26:104 )	K	26 - 104
69	X-RAY DIFFRACTION	69	( CHAIN K AND RESID 105:131 )	K	105 - 131
70	X-RAY DIFFRACTION	70	( CHAIN K AND RESID 132:157 )	K	132 - 157
71	X-RAY DIFFRACTION	71	( CHAIN K AND RESID 158:182 )	K	158 - 182
72	X-RAY DIFFRACTION	72	( CHAIN K AND RESID 183:192 )	K	183 - 192
73	X-RAY DIFFRACTION	73	( CHAIN L AND RESID 3:25 )	L	3 - 25
74	X-RAY DIFFRACTION	74	( CHAIN L AND RESID 26:36 )	L	26 - 36
75	X-RAY DIFFRACTION	75	( CHAIN L AND RESID 37:104 )	L	37 - 104
76	X-RAY DIFFRACTION	76	( CHAIN L AND RESID 105:131 )	L	105 - 131
77	X-RAY DIFFRACTION	77	( CHAIN L AND RESID 132:157 )	L	132 - 157
78	X-RAY DIFFRACTION	78	( CHAIN L AND RESID 158:168 )	L	158 - 168
79	X-RAY DIFFRACTION	79	( CHAIN L AND RESID 169:182 )	L	169 - 182
80	X-RAY DIFFRACTION	80	( CHAIN L AND RESID 183:192 )	L	183 - 192
81	X-RAY DIFFRACTION	81	( CHAIN M AND RESID 3:24 )	M	3 - 24
82	X-RAY DIFFRACTION	82	( CHAIN M AND RESID 25:91 )	M	25 - 91
83	X-RAY DIFFRACTION	83	( CHAIN M AND RESID 92:104 )	M	92 - 104
84	X-RAY DIFFRACTION	84	( CHAIN M AND RESID 105:131 )	M	105 - 131
85	X-RAY DIFFRACTION	85	( CHAIN M AND RESID 132:168 )	M	132 - 168
86	X-RAY DIFFRACTION	86	( CHAIN M AND RESID 169:192 )	M	169 - 192
87	X-RAY DIFFRACTION	87	( CHAIN N AND RESID 3:26 )	N	3 - 26
88	X-RAY DIFFRACTION	88	( CHAIN N AND RESID 27:53 )	N	27 - 53
89	X-RAY DIFFRACTION	89	( CHAIN N AND RESID 54:69 )	N	54 - 69
90	X-RAY DIFFRACTION	90	( CHAIN N AND RESID 70:91 )	N	70 - 91
91	X-RAY DIFFRACTION	91	( CHAIN N AND RESID 92:114 )	N	92 - 114
92	X-RAY DIFFRACTION	92	( CHAIN N AND RESID 115:131 )	N	115 - 131
93	X-RAY DIFFRACTION	93	( CHAIN N AND RESID 132:157 )	N	132 - 157
94	X-RAY DIFFRACTION	94	( CHAIN N AND RESID 158:168 )	N	158 - 168
95	X-RAY DIFFRACTION	95	( CHAIN N AND RESID 169:182 )	N	169 - 182
96	X-RAY DIFFRACTION	96	( CHAIN N AND RESID 183:192 )	N	183 - 192
97	X-RAY DIFFRACTION	97	( CHAIN O AND RESID 2:36 )	O	2 - 36
98	X-RAY DIFFRACTION	98	( CHAIN O AND RESID 37:91 )	O	37 - 91
99	X-RAY DIFFRACTION	99	( CHAIN O AND RESID 92:104 )	O	92 - 104
100	X-RAY DIFFRACTION	100	( CHAIN O AND RESID 105:131 )	O	105 - 131
101	X-RAY DIFFRACTION	101	( CHAIN O AND RESID 132:168 )	O	132 - 168
102	X-RAY DIFFRACTION	102	( CHAIN O AND RESID 169:182 )	O	169 - 182
103	X-RAY DIFFRACTION	103	( CHAIN O AND RESID 183:191 )	O	183 - 191
104	X-RAY DIFFRACTION	104	( CHAIN P AND RESID 3:25 )	P	3 - 25
105	X-RAY DIFFRACTION	105	( CHAIN P AND RESID 26:36 )	P	26 - 36
106	X-RAY DIFFRACTION	106	( CHAIN P AND RESID 37:82 )	P	37 - 82
107	X-RAY DIFFRACTION	107	( CHAIN P AND RESID 83:104 )	P	83 - 104
108	X-RAY DIFFRACTION	108	( CHAIN P AND RESID 105:131 )	P	105 - 131
109	X-RAY DIFFRACTION	109	( CHAIN P AND RESID 132:157 )	P	132 - 157
110	X-RAY DIFFRACTION	110	( CHAIN P AND RESID 158:168 )	P	158 - 168
111	X-RAY DIFFRACTION	111	( CHAIN P AND RESID 169:182 )	P	169 - 182
112	X-RAY DIFFRACTION	112	( CHAIN P AND RESID 183:192 )	P	183 - 192
113	X-RAY DIFFRACTION	113	( CHAIN Q AND RESID 3:24 )	Q	3 - 24
114	X-RAY DIFFRACTION	114	( CHAIN Q AND RESID 25:53 )	Q	25 - 53
115	X-RAY DIFFRACTION	115	( CHAIN Q AND RESID 54:69 )	Q	54 - 69
116	X-RAY DIFFRACTION	116	( CHAIN Q AND RESID 70:114 )	Q	70 - 114
117	X-RAY DIFFRACTION	117	( CHAIN Q AND RESID 115:131 )	Q	115 - 131
118	X-RAY DIFFRACTION	118	( CHAIN Q AND RESID 132:157 )	Q	132 - 157
119	X-RAY DIFFRACTION	119	( CHAIN Q AND RESID 158:168 )	Q	158 - 168
120	X-RAY DIFFRACTION	120	( CHAIN Q AND RESID 169:182 )	Q	169 - 182
121	X-RAY DIFFRACTION	121	( CHAIN Q AND RESID 183:192 )	Q	183 - 192
122	X-RAY DIFFRACTION	122	( CHAIN R AND RESID 3:24 )	R	3 - 24
123	X-RAY DIFFRACTION	123	( CHAIN R AND RESID 25:91 )	R	25 - 91
124	X-RAY DIFFRACTION	124	( CHAIN R AND RESID 92:104 )	R	92 - 104
125	X-RAY DIFFRACTION	125	( CHAIN R AND RESID 105:131 )	R	105 - 131
126	X-RAY DIFFRACTION	126	( CHAIN R AND RESID 132:168 )	R	132 - 168
127	X-RAY DIFFRACTION	127	( CHAIN R AND RESID 169:182 )	R	169 - 182
128	X-RAY DIFFRACTION	128	( CHAIN R AND RESID 183:192 )	R	183 - 192
129	X-RAY DIFFRACTION	129	( CHAIN S AND RESID 3:27 )	S	3 - 27
130	X-RAY DIFFRACTION	130	( CHAIN S AND RESID 28:82 )	S	28 - 82
131	X-RAY DIFFRACTION	131	( CHAIN S AND RESID 83:104 )	S	83 - 104
132	X-RAY DIFFRACTION	132	( CHAIN S AND RESID 105:131 )	S	105 - 131
133	X-RAY DIFFRACTION	133	( CHAIN S AND RESID 132:157 )	S	132 - 157
134	X-RAY DIFFRACTION	134	( CHAIN S AND RESID 158:182 )	S	158 - 182
135	X-RAY DIFFRACTION	135	( CHAIN S AND RESID 183:193 )	S	183 - 193
136	X-RAY DIFFRACTION	136	( CHAIN T AND RESID 3:24 )	T	3 - 24
137	X-RAY DIFFRACTION	137	( CHAIN T AND RESID 25:69 )	T	25 - 69
138	X-RAY DIFFRACTION	138	( CHAIN T AND RESID 70:104 )	T	70 - 104
139	X-RAY DIFFRACTION	139	( CHAIN T AND RESID 105:131 )	T	105 - 131
140	X-RAY DIFFRACTION	140	( CHAIN T AND RESID 132:157 )	T	132 - 157
141	X-RAY DIFFRACTION	141	( CHAIN T AND RESID 158:182 )	T	158 - 182
142	X-RAY DIFFRACTION	142	( CHAIN T AND RESID 183:192 )	T	183 - 192
143	X-RAY DIFFRACTION	143	( CHAIN U AND RESID 2:24 )	U	2 - 24
144	X-RAY DIFFRACTION	144	( CHAIN U AND RESID 25:36 )	U	25 - 36
145	X-RAY DIFFRACTION	145	( CHAIN U AND RESID 37:53 )	U	37 - 53
146	X-RAY DIFFRACTION	146	( CHAIN U AND RESID 54:82 )	U	54 - 82
147	X-RAY DIFFRACTION	147	( CHAIN U AND RESID 83:91 )	U	83 - 91
148	X-RAY DIFFRACTION	148	( CHAIN U AND RESID 92:104 )	U	92 - 104
149	X-RAY DIFFRACTION	149	( CHAIN U AND RESID 105:131 )	U	105 - 131
150	X-RAY DIFFRACTION	150	( CHAIN U AND RESID 132:157 )	U	132 - 157
151	X-RAY DIFFRACTION	151	( CHAIN U AND RESID 158:168 )	U	158 - 168
152	X-RAY DIFFRACTION	152	( CHAIN U AND RESID 169:182 )	U	169 - 182
153	X-RAY DIFFRACTION	153	( CHAIN U AND RESID 183:192 )	U	183 - 192
154	X-RAY DIFFRACTION	154	( CHAIN V AND RESID 3:36 )	V	3 - 36
155	X-RAY DIFFRACTION	155	( CHAIN V AND RESID 37:114 )	V	37 - 114
156	X-RAY DIFFRACTION	156	( CHAIN V AND RESID 115:182 )	V	115 - 182
157	X-RAY DIFFRACTION	157	( CHAIN V AND RESID 183:193 )	V	183 - 193
158	X-RAY DIFFRACTION	158	( CHAIN W AND RESID 18:53 )	W	18 - 53
159	X-RAY DIFFRACTION	159	( CHAIN W AND RESID 54:104 )	W	54 - 104
160	X-RAY DIFFRACTION	160	( CHAIN W AND RESID 105:131 )	W	105 - 131
161	X-RAY DIFFRACTION	161	( CHAIN W AND RESID 132:157 )	W	132 - 157
162	X-RAY DIFFRACTION	162	( CHAIN W AND RESID 158:168 )	W	158 - 168
163	X-RAY DIFFRACTION	163	( CHAIN W AND RESID 169:182 )	W	169 - 182
164	X-RAY DIFFRACTION	164	( CHAIN W AND RESID 183:191 )	W	183 - 191
165	X-RAY DIFFRACTION	165	( CHAIN X AND RESID 3:25 )	X	3 - 25
166	X-RAY DIFFRACTION	166	( CHAIN X AND RESID 26:104 )	X	26 - 104
167	X-RAY DIFFRACTION	167	( CHAIN X AND RESID 105:131 )	X	105 - 131
168	X-RAY DIFFRACTION	168	( CHAIN X AND RESID 132:168 )	X	132 - 168
169	X-RAY DIFFRACTION	169	( CHAIN X AND RESID 169:191 )	X	169 - 191
170	X-RAY DIFFRACTION	170	( CHAIN Y AND RESID 3:25 )	Y	3 - 25
171	X-RAY DIFFRACTION	171	( CHAIN Y AND RESID 26:82 )	Y	26 - 82
172	X-RAY DIFFRACTION	172	( CHAIN Y AND RESID 83:131 )	Y	83 - 131
173	X-RAY DIFFRACTION	173	( CHAIN Y AND RESID 132:168 )	Y	132 - 168
174	X-RAY DIFFRACTION	174	( CHAIN Y AND RESID 169:192 )	Y	169 - 192
175	X-RAY DIFFRACTION	175	( CHAIN Z AND RESID 3:24 )	Z	3 - 24
176	X-RAY DIFFRACTION	176	( CHAIN Z AND RESID 25:36 )	Z	25 - 36
177	X-RAY DIFFRACTION	177	( CHAIN Z AND RESID 37:53 )	Z	37 - 53
178	X-RAY DIFFRACTION	178	( CHAIN Z AND RESID 54:91 )	Z	54 - 91
179	X-RAY DIFFRACTION	179	( CHAIN Z AND RESID 92:104 )	Z	92 - 104
180	X-RAY DIFFRACTION	180	( CHAIN Z AND RESID 105:131 )	Z	105 - 131
181	X-RAY DIFFRACTION	181	( CHAIN Z AND RESID 132:157 )	Z	132 - 157
182	X-RAY DIFFRACTION	182	( CHAIN Z AND RESID 158:168 )	Z	158 - 168
183	X-RAY DIFFRACTION	183	( CHAIN Z AND RESID 169:182 )	Z	169 - 182
184	X-RAY DIFFRACTION	184	( CHAIN Z AND RESID 183:192 )	Z	183 - 192
185	X-RAY DIFFRACTION	185	( CHAIN a AND RESID 3:36 )	a	3 - 36
186	X-RAY DIFFRACTION	186	( CHAIN a AND RESID 37:53 )	a	37 - 53
187	X-RAY DIFFRACTION	187	( CHAIN a AND RESID 54:104 )	a	54 - 104
188	X-RAY DIFFRACTION	188	( CHAIN a AND RESID 105:131 )	a	105 - 131
189	X-RAY DIFFRACTION	189	( CHAIN a AND RESID 132:157 )	a	132 - 157
190	X-RAY DIFFRACTION	190	( CHAIN a AND RESID 158:182 )	a	158 - 182
191	X-RAY DIFFRACTION	191	( CHAIN a AND RESID 183:191 )	a	183 - 191
192	X-RAY DIFFRACTION	192	( CHAIN b AND RESID 3:24 )	b	3 - 24
193	X-RAY DIFFRACTION	193	( CHAIN b AND RESID 25:53 )	b	25 - 53
194	X-RAY DIFFRACTION	194	( CHAIN b AND RESID 54:82 )	b	54 - 82
195	X-RAY DIFFRACTION	195	( CHAIN b AND RESID 83:104 )	b	83 - 104
196	X-RAY DIFFRACTION	196	( CHAIN b AND RESID 105:131 )	b	105 - 131
197	X-RAY DIFFRACTION	197	( CHAIN b AND RESID 132:157 )	b	132 - 157
198	X-RAY DIFFRACTION	198	( CHAIN b AND RESID 158:167 )	b	158 - 167
199	X-RAY DIFFRACTION	199	( CHAIN b AND RESID 168:182 )	b	168 - 182
200	X-RAY DIFFRACTION	200	( CHAIN b AND RESID 183:192 )	b	183 - 192