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Yorodumi- PDB-7mk5: Crystal structure of Escherichia coli ClpP covalently inhibited b... -
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-Basic information
Entry | Database: PDB / ID: 7mk5 | ||||||
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Title | Crystal structure of Escherichia coli ClpP covalently inhibited by clipibicyclene | ||||||
Components | ATP-dependent Clp protease proteolytic subunit | ||||||
Keywords | HYDROLASE/HYDROLASE inhibitor / Inhibitor / Complex / Protease / HYDROLASE / HYDROLASE-HYDROLASE inhibitor complex | ||||||
Function / homology | Function and homology information HslUV protease complex / endopeptidase Clp complex / endopeptidase Clp / positive regulation of programmed cell death / response to temperature stimulus / ATP-dependent peptidase activity / protein quality control for misfolded or incompletely synthesized proteins / serine-type peptidase activity / proteasomal protein catabolic process / response to radiation ...HslUV protease complex / endopeptidase Clp complex / endopeptidase Clp / positive regulation of programmed cell death / response to temperature stimulus / ATP-dependent peptidase activity / protein quality control for misfolded or incompletely synthesized proteins / serine-type peptidase activity / proteasomal protein catabolic process / response to radiation / ATPase binding / response to heat / serine-type endopeptidase activity / proteolysis / membrane / identical protein binding / cytosol Similarity search - Function | ||||||
Biological species | Escherichia coli K-12 (bacteria) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.95 Å | ||||||
Authors | Culp, E.J. / Sychantha, D. / Hobson, C. / Pawlowski, A.J. / Prehna, G. / Wright, G.D. | ||||||
Funding support | Canada, 1items
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Citation | Journal: Nat Microbiol / Year: 2022 Title: ClpP inhibitors are produced by a widespread family of bacterial gene clusters. Authors: Culp, E.J. / Sychantha, D. / Hobson, C. / Pawlowski, A.C. / Prehna, G. / Wright, G.D. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7mk5.cif.gz | 3.1 MB | Display | PDBx/mmCIF format |
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PDB format | pdb7mk5.ent.gz | 2.4 MB | Display | PDB format |
PDBx/mmJSON format | 7mk5.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/mk/7mk5 ftp://data.pdbj.org/pub/pdb/validation_reports/mk/7mk5 | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
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