+Open data
-Basic information
Entry | Database: PDB / ID: 7lec | ||||||
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Title | HIV-1 Protease WT (NL4-3) in Complex with PU3 (LR3-69) | ||||||
Components | Protease | ||||||
Keywords | HYDROLASE/HYDROLASE INHIBITOR / HIV / NL4-3 PROTEASE / PROTEASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||
Function / homology | Function and homology information | ||||||
Biological species | Human immunodeficiency virus 1 | ||||||
Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 1.94 Å | ||||||
Authors | Lockbaum, G.J. / Rusere, L.N. / Henes, M. / Kosovrasti, K. / Lee, S.K. / Spielvogel, E. / Nalivaika, E.A. / Swanstrom, R. / KurtYilmaz, N. / Schiffer, C.A. / Ali, A. | ||||||
Funding support | United States, 1items
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Citation | Journal: To Be Published Title: HIV-1 Protease Inhibitors with a P1 Phosphonate Modification Maintain Potency against Drug Resistant Variants by Increased van der Waals Contacts with Flaps Residues Authors: Lockbaum, G.J. / Rusere, L.N. / Henes, M. / Kosovrasti, K. / Lee, S.K. / Spielvogel, E. / Nalivaika, E.A. / Swanstrom, R. / KurtYilmaz, N. / Schiffer, C.A. / Ali, A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7lec.cif.gz | 91.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7lec.ent.gz | 69.1 KB | Display | PDB format |
PDBx/mmJSON format | 7lec.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7lec_validation.pdf.gz | 819.4 KB | Display | wwPDB validaton report |
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Full document | 7lec_full_validation.pdf.gz | 823.7 KB | Display | |
Data in XML | 7lec_validation.xml.gz | 12.6 KB | Display | |
Data in CIF | 7lec_validation.cif.gz | 17.2 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/le/7lec ftp://data.pdbj.org/pub/pdb/validation_reports/le/7lec | HTTPS FTP |
-Related structure data
Related structure data | 7ldyC 7ldzC 7le0C 7le1C 7le2C 7le3C 7le4C 7le5C 7le6C 7le7C 7le8C 7le9C 7leaC 7lebC 7ledC 7leeC 7lefC 7legC 7lehC 7leiC 6dgxS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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