登録情報 | データベース: PDB / ID: 7l36 |
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タイトル | PEPCK steady-state structure with Mn and GTP |
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要素 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
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キーワード | LYASE / PEPCK / phosphoenolpyruvate carboxykinase / gluconeogensis |
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機能・相同性 | 機能・相同性情報
Gluconeogenesis / phosphoenolpyruvate carboxykinase activity / cellular response to potassium ion starvation / protein serine kinase activity (using GTP as donor) / response to methionine / 転移酵素; リンを含む基を移すもの; タンパク質-セリン/スレオニンキナーゼ / glycerol biosynthetic process from pyruvate / phosphoenolpyruvate carboxykinase (GTP) / phosphoenolpyruvate carboxykinase (GTP) activity / propionate catabolic process ...Gluconeogenesis / phosphoenolpyruvate carboxykinase activity / cellular response to potassium ion starvation / protein serine kinase activity (using GTP as donor) / response to methionine / 転移酵素; リンを含む基を移すもの; タンパク質-セリン/スレオニンキナーゼ / glycerol biosynthetic process from pyruvate / phosphoenolpyruvate carboxykinase (GTP) / phosphoenolpyruvate carboxykinase (GTP) activity / propionate catabolic process / cellular response to raffinose / tricarboxylic acid metabolic process / regulation of lipid biosynthetic process / response to interleukin-6 / cellular response to fructose stimulus / cellular hypotonic response / carboxylic acid binding / cellular hypotonic salinity response / cellular response to phorbol 13-acetate 12-myristate / oxaloacetate metabolic process / hepatocyte differentiation / positive regulation of memory T cell differentiation / cellular hyperosmotic response / glyceraldehyde-3-phosphate biosynthetic process / nucleoside diphosphate kinase activity / cellular hyperosmotic salinity response / response to lipid / cellular response to glucagon stimulus / response to starvation / cellular response to interleukin-1 / positive regulation of lipid biosynthetic process / cellular response to retinoic acid / cellular response to cAMP / response to nutrient levels / cellular response to dexamethasone stimulus / response to activity / gluconeogenesis / cellular response to glucose stimulus / response to bacterium / response to insulin / lipid metabolic process / cellular response to insulin stimulus / GDP binding / glucose metabolic process / glucose homeostasis / cellular response to tumor necrosis factor / manganese ion binding / cellular response to hypoxia / peptidyl-serine phosphorylation / response to lipopolysaccharide / GTP binding / magnesium ion binding / endoplasmic reticulum / positive regulation of transcription by RNA polymerase II / cytoplasm / cytosol類似検索 - 分子機能 Phosphoenolpyruvate carboxykinase, GTP-utilising / Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site / Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain / Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal / Phosphoenolpyruvate carboxykinase C-terminal P-loop domain / Phosphoenolpyruvate carboxykinase N-terminal domain / Phosphoenolpyruvate carboxykinase (GTP) signature. / Phosphoenolpyruvate carboxykinase, C-terminal / Phosphoenolpyruvate carboxykinase, N-terminal類似検索 - ドメイン・相同性 GUANOSINE-5'-TRIPHOSPHATE / : / Phosphoenolpyruvate carboxykinase, cytosolic [GTP]類似検索 - 構成要素 |
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生物種 | Rattus norvegicus (ドブネズミ) |
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手法 | X線回折 / シンクロトロン / フーリエ合成 / 解像度: 1.84 Å |
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データ登録者 | Clinger, J.A. / Moreau, D.W. / McLeod, M.J. / Holyoak, T. / Thorne, R.E. |
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資金援助 | 米国, カナダ, 2件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | 1R01GM127528-01 | 米国 | Natural Sciences and Engineering Research Council (NSERC, Canada) | | カナダ |
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引用 | ジャーナル: Iucrj / 年: 2021 タイトル: Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection. 著者: Clinger, J.A. / Moreau, D.W. / McLeod, M.J. / Holyoak, T. / Thorne, R.E. |
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履歴 | 登録 | 2020年12月17日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2021年10月13日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年10月18日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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