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- PDB-7k7y: Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9 -
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Open data
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Basic information
Entry | Database: PDB / ID: 7k7y | |||||||||||||||
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Title | Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9 | |||||||||||||||
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![]() | ANTITOXIN / Botulinum neurotoxin (BoNT) / VHH / receptor-binding domain / TOXIN | |||||||||||||||
Function / homology | ![]() Toxicity of botulinum toxin type E (botE) / negative regulation of neurotransmitter secretion / bontoxilysin / host cell presynaptic membrane / host cell cytoplasmic vesicle / host cell cytosol / protein transmembrane transporter activity / metalloendopeptidase activity / toxin activity / lipid binding ...Toxicity of botulinum toxin type E (botE) / negative regulation of neurotransmitter secretion / bontoxilysin / host cell presynaptic membrane / host cell cytoplasmic vesicle / host cell cytosol / protein transmembrane transporter activity / metalloendopeptidase activity / toxin activity / lipid binding / host cell plasma membrane / proteolysis / zinc ion binding / extracellular region / membrane Similarity search - Function | |||||||||||||||
Biological species | ![]() ![]() ![]() ![]() | |||||||||||||||
Method | ![]() ![]() ![]() | |||||||||||||||
![]() | Lam, K. / Jin, R. | |||||||||||||||
Funding support | ![]()
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![]() | ![]() Title: Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells. Authors: Lam, K.H. / Perry, K. / Shoemaker, C.B. / Jin, R. | |||||||||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 760.6 KB | Display | ![]() |
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PDB format | ![]() | 568.6 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 490 KB | Display | ![]() |
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Full document | ![]() | 515.5 KB | Display | |
Data in XML | ![]() | 114.1 KB | Display | |
Data in CIF | ![]() | 153 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 7k84C ![]() 3ffzS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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