登録情報 | データベース: PDB / ID: 7k6b |
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タイトル | Solution Structure of the Dysferlin C2A Domain in its Calcium-free State |
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要素 | Isoform 15 of Dysferlin |
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キーワード | MEMBRANE PROTEIN / membrane repair / calcium-binding / beta-sandwich |
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機能・相同性 | 機能・相同性情報
monocyte activation involved in immune response / T-tubule organization / vesicle fusion / regulation of neurotransmitter secretion / plasma membrane repair / macrophage activation involved in immune response / calcium-dependent phospholipid binding / negative regulation of phagocytosis / centriolar satellite / endocytic vesicle ...monocyte activation involved in immune response / T-tubule organization / vesicle fusion / regulation of neurotransmitter secretion / plasma membrane repair / macrophage activation involved in immune response / calcium-dependent phospholipid binding / negative regulation of phagocytosis / centriolar satellite / endocytic vesicle / Smooth Muscle Contraction / T-tubule / cytoplasmic vesicle membrane / phospholipid binding / sarcolemma / synaptic vesicle membrane / late endosome / early endosome / endosome / calcium ion binding / extracellular exosome / plasma membrane類似検索 - 分子機能 Ferlin A-domain / FerA (NUC095) domain / FerA / Ferlin B-domain / FerIin domain / Ferlin, C-terminal domain / Ferlin, second C2 domain / Ferlin family / Ferlin, third C2 domain / Ferlin, fourth C2 domain ...Ferlin A-domain / FerA (NUC095) domain / FerA / Ferlin B-domain / FerIin domain / Ferlin, C-terminal domain / Ferlin, second C2 domain / Ferlin family / Ferlin, third C2 domain / Ferlin, fourth C2 domain / Ferlin, fifth C2 domain / Ferlin, sixth C2 domain / Ferlin, first C2 domain / FerB (NUC096) domain / FerI (NUC094) domain / Ferlin C-terminus / FerB / FerI / Peroxin/Ferlin domain / Dysferlin domain, N-terminal region. / Dysferlin domain, C-terminal region. / C2 domain / Protein kinase C conserved region 2 (CalB) / C2 domain / C2 domain profile. / C2 domain superfamily類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Wang, Y. / Mercier, P. / Santamaria, L. / Shaw, G.S. |
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資金援助 | カナダ, 1件 組織 | 認可番号 | 国 |
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Canadian Institutes of Health Research (CIHR) | MOP-14606 | カナダ |
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引用 | ジャーナル: Biochem.J. / 年: 2021 タイトル: Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. 著者: Wang, Y. / Tadayon, R. / Santamaria, L. / Mercier, P. / Forristal, C.J. / Shaw, G.S. |
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履歴 | 登録 | 2020年9月19日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2021年1月27日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年6月14日 | Group: Database references / Other / カテゴリ: database_2 / pdbx_database_status Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data |
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改定 1.2 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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