- PDB-7dd1: Crystal structure of SRPK1 in complex with a peptide inhibitor -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: PDB / ID: 7dd1
Title
Crystal structure of SRPK1 in complex with a peptide inhibitor
Components
ARG-GLU-ARG-ALA-ARG-THR-ARG
SRSF protein kinase 1,SRSF protein kinase 1
Keywords
TRANSFERASE / RNA splicing / kinase inhibitor / Peptide drug
Function / homology
Function and homology information
protein serine/threonine kinase activity => GO:0004674 / sperm DNA condensation / regulation of mRNA processing / regulation of mRNA splicing, via spliceosome / negative regulation of viral genome replication / spliceosomal complex assembly / MAP kinase activity / positive regulation of viral genome replication / viral process / RNA splicing ...protein serine/threonine kinase activity => GO:0004674 / sperm DNA condensation / regulation of mRNA processing / regulation of mRNA splicing, via spliceosome / negative regulation of viral genome replication / spliceosomal complex assembly / MAP kinase activity / positive regulation of viral genome replication / viral process / RNA splicing / chromosome segregation / nuclear matrix / regulation of gene expression / non-specific serine/threonine protein kinase / protein kinase activity / intracellular signal transduction / nuclear speck / protein phosphorylation / innate immune response / protein serine kinase activity / protein serine/threonine kinase activity / chromatin / magnesium ion binding / endoplasmic reticulum / RNA binding / nucleoplasm / ATP binding / nucleus / plasma membrane / cytosol / cytoplasm Similarity search - Function
Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily Similarity search - Domain/homology
In the structure databanks used in Yorodumi, some data are registered as the other names, "COVID-19 virus" and "2019-nCoV". Here are the details of the virus and the list of structure data.
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)
EMDB accession codes are about to change! (news from PDBe EMDB page)
The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
The EM Navigator/Yorodumi systems omit the EMD- prefix.
Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator
Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.
Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi