登録情報 データベース : PDB / ID : 7cqd 構造の表示 ダウンロードとリンクタイトル The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 235 and 236 要素Heavy chain of antigen binding fragment, Fab of NZ-1 Light chain of antigen binding fragment, Fab of NZ-1 Putative zinc metalloprotease aq_1964,PA14 from Podoplanin,Putative zinc metalloprotease aq_1964 詳細キーワード HYDROLASE/IMMUNE SYSTEM / soluble domain / Fab complex / MEMBRANE PROTEIN / HYDROLASE-IMMUNE SYSTEM complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
lymphatic endothelial cell fate commitment / regulation of myofibroblast contraction / actin-mediated cell contraction / leading edge of lamellipodium / regulation of substrate adhesion-dependent cell spreading / positive regulation of extracellular matrix disassembly / chemokine binding / Specification of primordial germ cells / lymphangiogenesis / regulation of lamellipodium morphogenesis ... lymphatic endothelial cell fate commitment / regulation of myofibroblast contraction / actin-mediated cell contraction / leading edge of lamellipodium / regulation of substrate adhesion-dependent cell spreading / positive regulation of extracellular matrix disassembly / chemokine binding / Specification of primordial germ cells / lymphangiogenesis / regulation of lamellipodium morphogenesis / tetraspanin-enriched microdomain / positive regulation of platelet aggregation / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; その他のペプチターゼ / filopodium membrane / anchoring junction / wound healing, spreading of cells / microvillus membrane / lamellipodium membrane / Rho protein signal transduction / response to hyperoxia / lymph node development / positive regulation of epithelial to mesenchymal transition / GPVI-mediated activation cascade / ruffle / filopodium / cell projection / lung development / platelet activation / metalloendopeptidase activity / ruffle membrane / cell-cell adhesion / cell migration / lamellipodium / cell junction / regulation of cell shape / protein-folding chaperone binding / cytoplasmic vesicle / basolateral plasma membrane / cell adhesion / positive regulation of cell migration / membrane raft / apical plasma membrane / negative regulation of cell population proliferation / signaling receptor binding / negative regulation of apoptotic process / signal transduction / mitochondrion / proteolysis / membrane / metal ion binding / plasma membrane / cytosol 類似検索 - 分子機能 Podoplanin / Peptidase M50, putative membrane-associated zinc metallopeptidase / Peptidase M50 / Peptidase family M50 / PDZ domain 6 / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Neutral zinc metallopeptidases, zinc-binding region signature. 類似検索 - ドメイン・相同性 Putative zinc metalloprotease aq_1964 / Podoplanin 類似検索 - 構成要素生物種 Rattus norvegicus (ドブネズミ)Aquifex aeolicus VF5 (バクテリア)Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3.2 Å 詳細データ登録者 Tamura-Sakaguchi, R. / Aruga, R. / Nogi, T. 資金援助 日本, 1件 詳細 詳細を隠す組織 認可番号 国 Japan Society for the Promotion of Science (JSPS) 19H03170 日本
引用ジャーナル : Acta Crystallogr D Struct Biol / 年 : 2021タイトル : Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion.著者 : Tamura-Sakaguchi, R. / Aruga, R. / Hirose, M. / Ekimoto, T. / Miyake, T. / Hizukuri, Y. / Oi, R. / Kaneko, M.K. / Kato, Y. / Akiyama, Y. / Ikeguchi, M. / Iwasaki, K. / Nogi, T. 履歴 登録 2020年8月10日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2021年5月19日 Provider : repository / タイプ : Initial release改定 1.1 2023年11月29日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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