Entry | Database: PDB / ID: 7bjv |
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Title | Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI09181 |
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Components | - Ecdysone Receptor
- Ultraspiracle protein
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Keywords | TRANSCRIPTION / Nuclear Receptor / Ligand-Binding Domain / Ecdysone receptor / dibenzoylhydrazine |
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Function / homology | Function and homology information
nuclear steroid receptor activity / sequence-specific DNA binding / DNA-binding transcription factor activity / zinc ion binding / nucleusSimilarity search - Function Retinoid X receptor/HNF4 / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Ligand-binding domain of nuclear hormone receptor ...Retinoid X receptor/HNF4 / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Ligand-binding domain of nuclear hormone receptor / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Zinc finger, NHR/GATA-typeSimilarity search - Domain/homology |
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Biological species | Heliothis virescens (tobacco budworm) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 3.05 Å |
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Authors | Browning, C. / McEwen, A.G. / Billas, I.M.L. |
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Funding support | France, 1items Organization | Grant number | Country |
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French National Research Agency | ANR-10-INSB-05-01 | France |
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Citation | Journal: J Pestic Sci / Year: 2021 Title: Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP. Authors: Browning, C. / McEwen, A.G. / Mori, K. / Yokoi, T. / Moras, D. / Nakagawa, Y. / Billas, I.M.L. |
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History | Deposition | Jan 14, 2021 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Apr 7, 2021 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 31, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / citation / database_2 / pdbx_initial_refinement_model Item: _citation.country / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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