登録情報 | データベース: PDB / ID: 7auw |
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タイトル | Inhibitory complex of human meprin beta with mouse fetuin-B. |
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要素 | - Fetuin-B
- Meprin A subunit beta
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キーワード | HYDROLASE INHIBITOR / protease inhibitor complex / zinc metallopeptidase / cystatin-type modules / HYDROLASE |
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機能・相同性 | 機能・相同性情報
meprin B / meprin A complex / metalloendopeptidase inhibitor activity / negative regulation of endopeptidase activity / binding of sperm to zona pellucida / cysteine-type endopeptidase inhibitor activity / single fertilization / metalloendopeptidase activity / inflammatory response / proteolysis ...meprin B / meprin A complex / metalloendopeptidase inhibitor activity / negative regulation of endopeptidase activity / binding of sperm to zona pellucida / cysteine-type endopeptidase inhibitor activity / single fertilization / metalloendopeptidase activity / inflammatory response / proteolysis / extracellular space / extracellular region / zinc ion binding / identical protein binding / plasma membrane類似検索 - 分子機能 Proteinase inhibitor I25C, fetuin, conserved site / Fetuin-B-type cystatin domain / Fetuin family signature 1. / Fetuin family signature 2. / Fetuin-B-type cystatin domain profile. / Meprin alpha/beta subunit / Meprin peptidase domain / : / Astacin-like domain profile. / Peptidase M12A ...Proteinase inhibitor I25C, fetuin, conserved site / Fetuin-B-type cystatin domain / Fetuin family signature 1. / Fetuin family signature 2. / Fetuin-B-type cystatin domain profile. / Meprin alpha/beta subunit / Meprin peptidase domain / : / Astacin-like domain profile. / Peptidase M12A / Astacin (Peptidase family M12A) / Cystatin domain / MAM domain signature. / Cystatin-like domain / Cystatin domain / Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) / MATH domain / MAM domain, meprin/A5/mu / MAM domain / MAM domain profile. / MATH/TRAF domain / MATH/TRAF domain profile. / meprin and TRAF homology / Cystatin superfamily / TRAF-like / Peptidase, metallopeptidase / Zinc-dependent metalloprotease / Metallopeptidase, catalytic domain superfamily / EGF-like domain profile. / EGF-like domain / Neutral zinc metallopeptidases, zinc-binding region signature. / Concanavalin A-like lectin/glucanase domain superfamily類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト)
 Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.8 Å |
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データ登録者 | Eckhard, U. / Gomis-Ruth, F.X. |
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引用 | #1: ジャーナル: Sci Rep / 年: 2019タイトル: The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases. 著者: Guevara, T. / Koerschgen, H. / Cuppari, A. / Schmitz, C. / Kuske, M. / Yiallouros, I. / Floehr, J. / Jahnen-Dechent, W. / Stoecker, W. / Gomis-Ruth, F.X. |
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履歴 | 登録 | 2020年11月3日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2021年4月14日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月31日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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改定 1.2 | 2024年10月16日 | Group: Structure summary カテゴリ: pdbx_entry_details / pdbx_modification_feature Item: _pdbx_entry_details.has_protein_modification |
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