登録情報 | データベース: PDB / ID: 6zhs |
---|
タイトル | Uba1 bound to two E2 (Ubc13) molecules |
---|
要素 | - Ubiquitin-activating enzyme E1 1
- Ubiquitin-conjugating enzyme E2 13
|
---|
キーワード | LIGASE / Ubiquitin / E1 / Ubc13 |
---|
機能・相同性 | 機能・相同性情報
protein targeting to vacuolar membrane / Interleukin-1 signaling / Aggrephagy / Synthesis of active ubiquitin: roles of E1 and E2 enzymes / E1 ubiquitin-activating enzyme / ubiquitin conjugating enzyme complex / free ubiquitin chain polymerization / ubiquitin activating enzyme activity / E3 ubiquitin ligases ubiquitinate target proteins / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks ...protein targeting to vacuolar membrane / Interleukin-1 signaling / Aggrephagy / Synthesis of active ubiquitin: roles of E1 and E2 enzymes / E1 ubiquitin-activating enzyme / ubiquitin conjugating enzyme complex / free ubiquitin chain polymerization / ubiquitin activating enzyme activity / E3 ubiquitin ligases ubiquitinate target proteins / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks / postreplication repair / E2 ubiquitin-conjugating enzyme / fungal-type vacuole membrane / ubiquitin conjugating enzyme activity / Antigen processing: Ubiquitination & Proteasome degradation / protein K63-linked ubiquitination / protein polyubiquitination / ubiquitin-dependent protein catabolic process / protein ubiquitination / DNA damage response / ATP binding / nucleus / cytosol / cytoplasm類似検索 - 分子機能 Ubiquitin-activating enzyme E1, conserved site / Ubiquitin-activating enzyme signature 1. / Ubiquitin-activating enzyme E1 / Ubiquitin-activating enzyme E1, C-terminal / Ubiquitin-activating enzyme E1, FCCH domain / Ubiquitin-activating enzyme E1, four-helix bundle / Ubiquitin-activating enzyme E1, C-terminal domain superfamily / Ubiquitin-activating enzyme E1, SCCH domain / Ubiquitin-activating enzyme E1, FCCH domain superfamily / Ubiquitin fold domain ...Ubiquitin-activating enzyme E1, conserved site / Ubiquitin-activating enzyme signature 1. / Ubiquitin-activating enzyme E1 / Ubiquitin-activating enzyme E1, C-terminal / Ubiquitin-activating enzyme E1, FCCH domain / Ubiquitin-activating enzyme E1, four-helix bundle / Ubiquitin-activating enzyme E1, C-terminal domain superfamily / Ubiquitin-activating enzyme E1, SCCH domain / Ubiquitin-activating enzyme E1, FCCH domain superfamily / Ubiquitin fold domain / Ubiquitin-activating enzyme E1 FCCH domain / Ubiquitin-activating enzyme E1 four-helix bundle / Ubiquitin-activating enzyme e1 C-terminal domain / Ubiquitin-activating enzyme, SCCH domain / Ubiquitin-activating enzyme, SCCH domain / Ubiquitin/SUMO-activating enzyme E1-like / Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 / Ubiquitin-activating enzyme E1, Cys active site / Ubiquitin-activating enzyme active site. / ThiF/MoeB/HesA family / Ubiquitin-activating enzyme / THIF-type NAD/FAD binding fold / ThiF family / : / Ubiquitin-conjugating enzyme, active site / Ubiquitin-conjugating (UBC) active site signature. / Ubiquitin-conjugating enzyme E2, catalytic domain homologues / Ubiquitin-conjugating enzyme E2 / Ubiquitin-conjugating enzyme / Ubiquitin-conjugating (UBC) core domain profile. / Ubiquitin-conjugating enzyme/RWD-like類似検索 - ドメイン・相同性 Ubiquitin-activating enzyme E1 1 / Ubiquitin-conjugating enzyme E2 13類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_yeast.gif) Saccharomyces cerevisiae (パン酵母) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.35 Å |
---|
データ登録者 | Misra, M. / Schindelin, H. |
---|
資金援助 | ドイツ, 1件 組織 | 認可番号 | 国 |
---|
German Research Foundation (DFG) | SCHI 425-6/1 | ドイツ |
|
---|
引用 | ジャーナル: To Be Published タイトル: ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. 著者: Misra, M. / Schaefer, A. / Kuhn, M. / Pluska, L. / Tessmer, I. / Sommer, T. / Schindelin, H. |
---|
履歴 | 登録 | 2020年6月23日 | 登録サイト: PDBE / 処理サイト: PDBE |
---|
改定 1.0 | 2022年1月12日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2024年1月24日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
---|
|
---|