登録情報 | データベース: PDB / ID: 6z7u |
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タイトル | Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation |
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要素 | Myosin-2 heavy chain |
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キーワード | MOTOR PROTEIN / myosin / motorprotein / blebbistatin / ADP-release / inhibitor / complex / hydrolase |
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機能・相同性 | 機能・相同性情報
pseudopodium retraction / uropod retraction / cytoplasmic actin-based contraction involved in forward cell motility / phagocytic cup base / pathogen-containing vacuole / response to differentiation-inducing factor 1 / equatorial cell cortex / contractile actin filament bundle assembly / cell trailing edge / contractile vacuole organization ...pseudopodium retraction / uropod retraction / cytoplasmic actin-based contraction involved in forward cell motility / phagocytic cup base / pathogen-containing vacuole / response to differentiation-inducing factor 1 / equatorial cell cortex / contractile actin filament bundle assembly / cell trailing edge / contractile vacuole organization / myosin filament assembly / aggregation involved in sorocarp development / culmination involved in sorocarp development / RHO GTPases activate PAKs / adenyl nucleotide binding / calcium-dependent ATPase activity / hypotonic response / actomyosin contractile ring / uropod / apical cortex / detection of mechanical stimulus / negative regulation of actin filament polymerization / actin-myosin filament sliding / bleb assembly / substrate-dependent cell migration, cell extension / actomyosin / filopodium assembly / myosin filament / early phagosome / myosin II complex / cortical actin cytoskeleton organization / cortical actin cytoskeleton / microfilament motor activity / pseudopodium / cytoskeletal motor activity / mitotic cytokinesis / cleavage furrow / response to cAMP / response to mechanical stimulus / 14-3-3 protein binding / extracellular matrix / cell motility / response to hydrogen peroxide / chemotaxis / actin filament binding / intracellular protein localization / regulation of cell shape / cytoplasmic vesicle / cell cortex / calmodulin binding / cytoskeleton / ATP binding / identical protein binding / cytosol / cytoplasm類似検索 - 分子機能 Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #60 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #530 / Myosin tail / Myosin tail / Myosin N-terminal SH3-like domain / Myosin S1 fragment, N-terminal / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Myosin head, motor domain / Myosin head (motor domain) ...Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #60 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #530 / Myosin tail / Myosin tail / Myosin N-terminal SH3-like domain / Myosin S1 fragment, N-terminal / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Myosin head, motor domain / Myosin head (motor domain) / Myosin motor domain profile. / Myosin. Large ATPases. / IQ motif profile. / Kinesin motor domain superfamily / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / Up-down Bundle / P-loop containing nucleoside triphosphate hydrolase / Mainly Alpha類似検索 - ドメイン・相同性 ADENOSINE-5'-DIPHOSPHATE / Chem-BIT / Myosin-2 heavy chain類似検索 - 構成要素 |
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生物種 |  Dictyostelium discoideum (キイロタマホコリカビ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.58 Å |
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データ登録者 | Ewert, W. / Preller, M. |
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資金援助 | ドイツ, 1件 組織 | 認可番号 | 国 |
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German Research Foundation (DFG) | PR 1478/2-1 | ドイツ |
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引用 | ジャーナル: Int J Mol Sci / 年: 2020 タイトル: Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke. 著者: Ewert, W. / Franz, P. / Tsiavaliaris, G. / Preller, M. |
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履歴 | 登録 | 2020年6月1日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2020年10月21日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年10月28日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.pdbx_database_id_PubMed ..._citation.journal_volume / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.identifier_ORCID |
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改定 1.2 | 2024年1月24日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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