Entry | Database: PDB / ID: 6y2h |
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Title | The crystal structure of human chloride intracellular channel protein 5 |
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Components | Chloride intracellular channel protein 5 |
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Keywords | TRANSPORT PROTEIN / Chloride intracellular channel / CLIC / metamorphic protein |
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Function / homology | Function and homology information
stereocilium base / response to stimulus / Sensory processing of sound by outer hair cells of the cochlea / Sensory processing of sound by inner hair cells of the cochlea / chloride transport / chloride channel activity / chloride channel complex / visual perception / female pregnancy / sensory perception of sound ...stereocilium base / response to stimulus / Sensory processing of sound by outer hair cells of the cochlea / Sensory processing of sound by inner hair cells of the cochlea / chloride transport / chloride channel activity / chloride channel complex / visual perception / female pregnancy / sensory perception of sound / actin cytoskeleton / cell cortex / apical plasma membrane / centrosome / Golgi apparatus / mitochondrion / extracellular exosomeSimilarity search - Function CLIC5, C-terminal GST domain / Intracellular chloride channel / Glutathione S-transferase, N-terminal domain / Glutathione S-transferase, C-terminal domain / Glutathione transferase family / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 - #10 / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 / Glutathione S-transferase, C-terminal-like / Soluble glutathione S-transferase C-terminal domain profile. / Glutathione S-transferase, N-terminal ...CLIC5, C-terminal GST domain / Intracellular chloride channel / Glutathione S-transferase, N-terminal domain / Glutathione S-transferase, C-terminal domain / Glutathione transferase family / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 - #10 / Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 / Glutathione S-transferase, C-terminal-like / Soluble glutathione S-transferase C-terminal domain profile. / Glutathione S-transferase, N-terminal / Glutathione S-transferase, C-terminal domain superfamily / Glutaredoxin / Glutaredoxin / Thioredoxin-like superfamily / Up-down Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.154 Å |
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Authors | Ferofontov, A. / Giladi, M. / Haitin, Y. |
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Funding support | Israel, 4items Organization | Grant number | Country |
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Israel Science Foundation | 1721/16 | Israel | Israel Science Foundation | 1775/12 | Israel | German-Israeli Foundation for Research and Development | I-2425-418.13/2016 | Israel | Other private | ICRF 01214 | Israel |
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Citation | Journal: Faseb J. / Year: 2020 Title: Conserved cysteine dioxidation enhances membrane interaction of human Cl - intracellular channel 5. Authors: Ferofontov, A. / Vankova, P. / Man, P. / Giladi, M. / Haitin, Y. |
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History | Deposition | Feb 16, 2020 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | May 20, 2020 | Provider: repository / Type: Initial release |
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Revision 1.1 | Aug 26, 2020 | Group: Database references / Category: citation Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.title / _citation.year |
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Revision 1.2 | Sep 2, 2020 | Group: Database references / Category: citation / Item: _citation.pdbx_database_id_PubMed / _citation.title |
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Revision 1.3 | Sep 30, 2020 | Group: Database references / Category: citation / Item: _citation.title |
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Revision 1.4 | Dec 2, 2020 | Group: Database references / Category: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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Revision 1.5 | Jan 24, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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