登録情報 | データベース: PDB / ID: 6uv4 |
---|
タイトル | Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-18a-oligo1 |
---|
要素 | - 18a_oligo1
- Probable ATP-dependent RNA helicase DDX17
|
---|
キーワード | RNA BINDING PROTEIN/RNA / DEAD-box ATPase / RNA helicase / RNA binding / RNA BINDING PROTEIN / RNA BINDING PROTEIN-RNA complex |
---|
機能・相同性 | 機能・相同性情報
regulation of skeletal muscle cell differentiation / alternative mRNA splicing, via spliceosome / miRNA metabolic process / ATP-dependent activity, acting on RNA / regulatory ncRNA-mediated gene silencing / myoblast differentiation / regulation of alternative mRNA splicing, via spliceosome / immune system process / androgen receptor signaling pathway / epithelial to mesenchymal transition ...regulation of skeletal muscle cell differentiation / alternative mRNA splicing, via spliceosome / miRNA metabolic process / ATP-dependent activity, acting on RNA / regulatory ncRNA-mediated gene silencing / myoblast differentiation / regulation of alternative mRNA splicing, via spliceosome / immune system process / androgen receptor signaling pathway / epithelial to mesenchymal transition / estrogen receptor signaling pathway / RNA processing / ribonucleoprotein complex binding / SUMOylation of transcription cofactors / mRNA 3'-UTR binding / rRNA processing / defense response to virus / RNA helicase activity / transcription coactivator activity / RNA helicase / nuclear speck / ribonucleoprotein complex / regulation of transcription by RNA polymerase II / nucleolus / positive regulation of transcription by RNA polymerase II / ATP hydrolysis activity / RNA binding / nucleoplasm / ATP binding / membrane / nucleus / cytosol / cytoplasm類似検索 - 分子機能 DEAD box protein 17, ATP-binding domain / DEAD-box subfamily ATP-dependent helicases signature. / ATP-dependent RNA helicase DEAD-box, conserved site / RNA helicase, DEAD-box type, Q motif / DEAD-box RNA helicase Q motif profile. / DEAD/DEAH box helicase / DEAD/DEAH box helicase domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. ...DEAD box protein 17, ATP-binding domain / DEAD-box subfamily ATP-dependent helicases signature. / ATP-dependent RNA helicase DEAD-box, conserved site / RNA helicase, DEAD-box type, Q motif / DEAD-box RNA helicase Q motif profile. / DEAD/DEAH box helicase / DEAD/DEAH box helicase domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / P-loop containing nucleoside triphosphate hydrolase類似検索 - ドメイン・相同性 ADENOSINE-5'-DIPHOSPHATE / BERYLLIUM TRIFLUORIDE ION / RNA / Probable ATP-dependent RNA helicase DDX17類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.7 Å |
---|
データ登録者 | Ngo, T.D. / Partin, A.C. / Nam, Y. |
---|
資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
---|
National Institutes of Health/National Human Genome Research Institute (NIH/NHGRI) | | 米国 |
|
---|
引用 | ジャーナル: Cell Rep / 年: 2019 タイトル: RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis. 著者: Ngo, T.D. / Partin, A.C. / Nam, Y. |
---|
履歴 | 登録 | 2019年11月1日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2020年1月1日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2020年1月15日 | Group: Structure summary / カテゴリ: struct / Item: _struct.title |
---|
改定 1.2 | 2024年3月6日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr2_auth_seq_id |
---|
改定 1.3 | 2024年4月3日 | Group: Refinement description / カテゴリ: pdbx_initial_refinement_model |
---|
|
---|