- PDB-6uha: Open-form Crystal Structure of Human RYR Receptor 3 ( 848-1055) -
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Open data
ID or keywords:
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Basic information
Entry
Database: PDB / ID: 6uha
Title
Open-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
Components
Ryanodine receptor 3
Keywords
METAL TRANSPORT / Type 3 Ryanodine Receptor / Alpha Fold / MCSG / Structural Genomics / Midwest Center for Structural Genomics / PSI-Biology
Function / homology
Function and homology information
calcium-induced calcium release activity / cellular response to magnesium ion / ryanodine-sensitive calcium-release channel activity / release of sequestered calcium ion into cytosol by sarcoplasmic reticulum / cellular response to ATP / cellular response to caffeine / intracellularly gated calcium channel activity / smooth endoplasmic reticulum / striated muscle contraction / release of sequestered calcium ion into cytosol ...calcium-induced calcium release activity / cellular response to magnesium ion / ryanodine-sensitive calcium-release channel activity / release of sequestered calcium ion into cytosol by sarcoplasmic reticulum / cellular response to ATP / cellular response to caffeine / intracellularly gated calcium channel activity / smooth endoplasmic reticulum / striated muscle contraction / release of sequestered calcium ion into cytosol / Ion homeostasis / sarcoplasmic reticulum membrane / calcium channel complex / cellular response to calcium ion / calcium ion transmembrane transport / Stimuli-sensing channels / sarcolemma / Z disc / intracellular calcium ion homeostasis / calcium ion transport / protein homotetramerization / calmodulin binding / calcium ion binding / membrane Similarity search - Function
Mass: 18.015 Da / Num. of mol.: 30 / Source method: isolated from a natural source / Formula: H2O
Has ligand of interest
N
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2.95 Å3/Da / Density % sol: 58.36 %
Crystal grow
Temperature: 297 K / Method: vapor diffusion, sitting drop / pH: 8.5 Details: PEG3350 15%, protein in co-crystallization with 30mM Caffeine and 10mM ATP
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Data collection
Diffraction
Mean temperature: 100 K / Serial crystal experiment: N